|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 35131 |
FusionGeneSummary for SNHG3_CUL2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SNHG3_CUL2 | Fusion gene ID: 35131 | Hgene | Tgene | Gene symbol | SNHG3 | CUL2 | Gene ID | 8420 | 8453 |
| Gene name | small nucleolar RNA host gene 3 | cullin 2 | |
| Synonyms | NCRNA00014|RNU17C|RNU17D|U17HG|U17HG-A|U17HG-AB | - | |
| Cytomap | 1p35.3 | 10p11.21 | |
| Type of gene | ncRNA | protein-coding | |
| Description | U17 small nucleolar RNA hostsmall nucleolar RNA host gene (non-protein coding) 3small nucleolar RNA host gene 3 (non-protein coding) | cullin-2CUL-2testis secretory sperm-binding protein Li 238E | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q13617 | ||
| Ensembl transtripts involved in fusion gene | ENST00000364938, | ENST00000374746, ENST00000374748, ENST00000374749, ENST00000374751, ENST00000602371, ENST00000374742, ENST00000537177, ENST00000478044, | |
| Fusion gene scores | * DoF score | 15 X 7 X 4=420 | 4 X 4 X 4=64 |
| # samples | 15 | 5 | |
| ** MAII score | log2(15/420*10)=-1.48542682717024 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(5/64*10)=-0.356143810225275 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SNHG3 [Title/Abstract] AND CUL2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BG256861 | SNHG3 | chr1 | 28834672 | + | CUL2 | chr10 | 35360268 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000364938 | ENST00000374746 | SNHG3 | chr1 | 28834672 | + | CUL2 | chr10 | 35360268 | - |
| intron-5UTR | ENST00000364938 | ENST00000374748 | SNHG3 | chr1 | 28834672 | + | CUL2 | chr10 | 35360268 | - |
| intron-5UTR | ENST00000364938 | ENST00000374749 | SNHG3 | chr1 | 28834672 | + | CUL2 | chr10 | 35360268 | - |
| intron-5UTR | ENST00000364938 | ENST00000374751 | SNHG3 | chr1 | 28834672 | + | CUL2 | chr10 | 35360268 | - |
| intron-5UTR | ENST00000364938 | ENST00000602371 | SNHG3 | chr1 | 28834672 | + | CUL2 | chr10 | 35360268 | - |
| intron-5UTR | ENST00000364938 | ENST00000374742 | SNHG3 | chr1 | 28834672 | + | CUL2 | chr10 | 35360268 | - |
| intron-5UTR | ENST00000364938 | ENST00000537177 | SNHG3 | chr1 | 28834672 | + | CUL2 | chr10 | 35360268 | - |
| intron-5UTR | ENST00000364938 | ENST00000478044 | SNHG3 | chr1 | 28834672 | + | CUL2 | chr10 | 35360268 | - |
Top |
FusionProtFeatures for SNHG3_CUL2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SNHG3 | CUL2 |