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Center for Computational Systems Medicine
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FusionGeneSummary

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Fusion gene ID: 35101

FusionGeneSummary for SNHG12_SRRT

check button Fusion gene summary
Fusion gene informationFusion gene name: SNHG12_SRRT
Fusion gene ID: 35101
HgeneTgene
Gene symbol

SNHG12

SRRT

Gene ID

85028

51593

Gene namesmall nucleolar RNA host gene 12serrate, RNA effector molecule
SynonymsASLNC04080|C1orf79|LINC00100|NCRNA00100|PNAS-123ARS2|ASR2|serrate
Cytomap

1p35.3

7q22.1

Type of genencRNAprotein-coding
Descriptionlong intergenic non-protein coding RNA 100small nucleolar RNA host gene 12 (non-protein coding)serrate RNA effector molecule homologarsenate resistance protein 2arsenate resistance protein ARS2arsenite resistance proteinarsenite-resistance protein 2
Modification date2018052020180519
UniProtAcc

Q9BXP5

Ensembl transtripts involved in fusion geneENST00000475441, ENST00000531126, 
ENST00000488745, ENST00000483436, 
ENST00000384581, ENST00000384584, 
ENST00000384342, 
ENST00000457580, 
ENST00000388793, ENST00000432932, 
ENST00000347433, 
Fusion gene scores* DoF score3 X 2 X 3=185 X 5 X 2=50
# samples 35
** MAII scorelog2(3/18*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
log2(5/50*10)=0
Context

PubMed: SNHG12 [Title/Abstract] AND SRRT [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS3.1R73443SNHG12chr1

28908310

-SRRTchr7

100485690

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
intron-3CDSENST00000475441ENST00000457580SNHG12chr1

28908310

-SRRTchr7

100485690

+
intron-3CDSENST00000475441ENST00000388793SNHG12chr1

28908310

-SRRTchr7

100485690

+
intron-3CDSENST00000475441ENST00000432932SNHG12chr1

28908310

-SRRTchr7

100485690

+
intron-3CDSENST00000475441ENST00000347433SNHG12chr1

28908310

-SRRTchr7

100485690

+
intron-3CDSENST00000531126ENST00000457580SNHG12chr1

28908310

-SRRTchr7

100485690

+
intron-3CDSENST00000531126ENST00000388793SNHG12chr1

28908310

-SRRTchr7

100485690

+
intron-3CDSENST00000531126ENST00000432932SNHG12chr1

28908310

-SRRTchr7

100485690

+
intron-3CDSENST00000531126ENST00000347433SNHG12chr1

28908310

-SRRTchr7

100485690

+
intron-3CDSENST00000488745ENST00000457580SNHG12chr1

28908310

-SRRTchr7

100485690

+
intron-3CDSENST00000488745ENST00000388793SNHG12chr1

28908310

-SRRTchr7

100485690

+
intron-3CDSENST00000488745ENST00000432932SNHG12chr1

28908310

-SRRTchr7

100485690

+
intron-3CDSENST00000488745ENST00000347433SNHG12chr1

28908310

-SRRTchr7

100485690

+
intron-3CDSENST00000483436ENST00000457580SNHG12chr1

28908310

-SRRTchr7

100485690

+
intron-3CDSENST00000483436ENST00000388793SNHG12chr1

28908310

-SRRTchr7

100485690

+
intron-3CDSENST00000483436ENST00000432932SNHG12chr1

28908310

-SRRTchr7

100485690

+
intron-3CDSENST00000483436ENST00000347433SNHG12chr1

28908310

-SRRTchr7

100485690

+
intron-3CDSENST00000384581ENST00000457580SNHG12chr1

28908310

-SRRTchr7

100485690

+
intron-3CDSENST00000384581ENST00000388793SNHG12chr1

28908310

-SRRTchr7

100485690

+
intron-3CDSENST00000384581ENST00000432932SNHG12chr1

28908310

-SRRTchr7

100485690

+
intron-3CDSENST00000384581ENST00000347433SNHG12chr1

28908310

-SRRTchr7

100485690

+
intron-3CDSENST00000384584ENST00000457580SNHG12chr1

28908310

-SRRTchr7

100485690

+
intron-3CDSENST00000384584ENST00000388793SNHG12chr1

28908310

-SRRTchr7

100485690

+
intron-3CDSENST00000384584ENST00000432932SNHG12chr1

28908310

-SRRTchr7

100485690

+
intron-3CDSENST00000384584ENST00000347433SNHG12chr1

28908310

-SRRTchr7

100485690

+
intron-3CDSENST00000384342ENST00000457580SNHG12chr1

28908310

-SRRTchr7

100485690

+
intron-3CDSENST00000384342ENST00000388793SNHG12chr1

28908310

-SRRTchr7

100485690

+
intron-3CDSENST00000384342ENST00000432932SNHG12chr1

28908310

-SRRTchr7

100485690

+
intron-3CDSENST00000384342ENST00000347433SNHG12chr1

28908310

-SRRTchr7

100485690

+

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FusionProtFeatures for SNHG12_SRRT


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
SNHG12

SRRT

Q9BXP5