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Fusion gene ID: 3495 |
FusionGeneSummary for ATP8A1_ATP8A1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ATP8A1_ATP8A1 | Fusion gene ID: 3495 | Hgene | Tgene | Gene symbol | ATP8A1 | ATP8A1 | Gene ID | 10396 | 10396 |
| Gene name | ATPase phospholipid transporting 8A1 | ATPase phospholipid transporting 8A1 | |
| Synonyms | ATPASEII|ATPIA|ATPP2 | ATPASEII|ATPIA|ATPP2 | |
| Cytomap | 4p13 | 4p13 | |
| Type of gene | protein-coding | protein-coding | |
| Description | phospholipid-transporting ATPase IAATPase IIATPase class I type 8A member 1ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1P4-ATPase flippase complex alpha subunit ATP8A1aminophospholipid translocasechromaffin granule ATPase | phospholipid-transporting ATPase IAATPase IIATPase class I type 8A member 1ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1P4-ATPase flippase complex alpha subunit ATP8A1aminophospholipid translocasechromaffin granule ATPase | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q9Y2Q0 | Q9Y2Q0 | |
| Ensembl transtripts involved in fusion gene | ENST00000381668, ENST00000264449, ENST00000510289, | ENST00000381668, ENST00000264449, ENST00000510289, | |
| Fusion gene scores | * DoF score | 7 X 7 X 5=245 | 2 X 2 X 2=8 |
| # samples | 7 | 2 | |
| ** MAII score | log2(7/245*10)=-1.8073549220576 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: ATP8A1 [Title/Abstract] AND ATP8A1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | AA740981 | ATP8A1 | chr4 | 42424196 | + | ATP8A1 | chr4 | 42422050 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-intron | ENST00000381668 | ENST00000381668 | ATP8A1 | chr4 | 42424196 | + | ATP8A1 | chr4 | 42422050 | + |
| intron-intron | ENST00000381668 | ENST00000264449 | ATP8A1 | chr4 | 42424196 | + | ATP8A1 | chr4 | 42422050 | + |
| intron-intron | ENST00000381668 | ENST00000510289 | ATP8A1 | chr4 | 42424196 | + | ATP8A1 | chr4 | 42422050 | + |
| intron-intron | ENST00000264449 | ENST00000381668 | ATP8A1 | chr4 | 42424196 | + | ATP8A1 | chr4 | 42422050 | + |
| intron-intron | ENST00000264449 | ENST00000264449 | ATP8A1 | chr4 | 42424196 | + | ATP8A1 | chr4 | 42422050 | + |
| intron-intron | ENST00000264449 | ENST00000510289 | ATP8A1 | chr4 | 42424196 | + | ATP8A1 | chr4 | 42422050 | + |
| intron-intron | ENST00000510289 | ENST00000381668 | ATP8A1 | chr4 | 42424196 | + | ATP8A1 | chr4 | 42422050 | + |
| intron-intron | ENST00000510289 | ENST00000264449 | ATP8A1 | chr4 | 42424196 | + | ATP8A1 | chr4 | 42422050 | + |
| intron-intron | ENST00000510289 | ENST00000510289 | ATP8A1 | chr4 | 42424196 | + | ATP8A1 | chr4 | 42422050 | + |
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FusionProtFeatures for ATP8A1_ATP8A1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ATP8A1 | ATP8A1 |