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Fusion gene ID: 34588 |
FusionGeneSummary for SLC6A14_SLC6A14 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SLC6A14_SLC6A14 | Fusion gene ID: 34588 | Hgene | Tgene | Gene symbol | SLC6A14 | SLC6A14 | Gene ID | 11254 | 11254 |
| Gene name | solute carrier family 6 member 14 | solute carrier family 6 member 14 | |
| Synonyms | BMIQ11 | BMIQ11 | |
| Cytomap | Xq23 | Xq23 | |
| Type of gene | protein-coding | protein-coding | |
| Description | sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)amino acid transporter ATB0+amino acid transporter B0+solute carrier family 6 (amino acid transporter), member 14solute carrier family 6 (neurotransmitter transporter), membe | sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)amino acid transporter ATB0+amino acid transporter B0+solute carrier family 6 (amino acid transporter), member 14solute carrier family 6 (neurotransmitter transporter), membe | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q9UN76 | Q9UN76 | |
| Ensembl transtripts involved in fusion gene | ENST00000371900, ENST00000463626, | ENST00000371900, ENST00000463626, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 2 X 2 X 1=4 |
| # samples | 1 | 2 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(2/4*10)=2.32192809488736 | |
| Context | PubMed: SLC6A14 [Title/Abstract] AND SLC6A14 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | SLC6A14 | GO:0009636 | response to toxic substance | 17575980 |
| Tgene | SLC6A14 | GO:0009636 | response to toxic substance | 17575980 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BU685498 | SLC6A14 | chrX | 115580157 | - | SLC6A14 | chrX | 115580202 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-intron | ENST00000371900 | ENST00000371900 | SLC6A14 | chrX | 115580157 | - | SLC6A14 | chrX | 115580202 | + |
| intron-intron | ENST00000371900 | ENST00000463626 | SLC6A14 | chrX | 115580157 | - | SLC6A14 | chrX | 115580202 | + |
| intron-intron | ENST00000463626 | ENST00000371900 | SLC6A14 | chrX | 115580157 | - | SLC6A14 | chrX | 115580202 | + |
| intron-intron | ENST00000463626 | ENST00000463626 | SLC6A14 | chrX | 115580157 | - | SLC6A14 | chrX | 115580202 | + |
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FusionProtFeatures for SLC6A14_SLC6A14 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SLC6A14 | SLC6A14 |