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Fusion gene ID: 3450 |
FusionGeneSummary for ATP6V0D1_GFOD2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ATP6V0D1_GFOD2 | Fusion gene ID: 3450 | Hgene | Tgene | Gene symbol | ATP6V0D1 | GFOD2 | Gene ID | 9114 | 81577 |
| Gene name | ATPase H+ transporting V0 subunit d1 | glucose-fructose oxidoreductase domain containing 2 | |
| Synonyms | ATP6D|ATP6DV|P39|VATX|VMA6|VPATPD | - | |
| Cytomap | 16q22.1 | 16q22.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | V-type proton ATPase subunit d 132 kDa accessory proteinATPase, H+ transporting, lysosomal (vacuolar proton pump), member DATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1H(+)-transporting two-sector ATPase, subunit DV-ATPase 40 KDa accessory | glucose-fructose oxidoreductase domain-containing protein 2 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | P61421 | Q3B7J2 | |
| Ensembl transtripts involved in fusion gene | ENST00000290949, ENST00000540149, ENST00000602876, ENST00000567694, | ENST00000602377, ENST00000268797, | |
| Fusion gene scores | * DoF score | 6 X 4 X 3=72 | 4 X 2 X 4=32 |
| # samples | 6 | 4 | |
| ** MAII score | log2(6/72*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/32*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: ATP6V0D1 [Title/Abstract] AND GFOD2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | SKCM | TCGA-BF-A5ER-01A | ATP6V0D1 | chr16 | 67514860 | - | GFOD2 | chr16 | 67719705 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-5UTR | ENST00000290949 | ENST00000602377 | ATP6V0D1 | chr16 | 67514860 | - | GFOD2 | chr16 | 67719705 | - |
| 5CDS-5UTR | ENST00000290949 | ENST00000268797 | ATP6V0D1 | chr16 | 67514860 | - | GFOD2 | chr16 | 67719705 | - |
| 5CDS-5UTR | ENST00000540149 | ENST00000602377 | ATP6V0D1 | chr16 | 67514860 | - | GFOD2 | chr16 | 67719705 | - |
| 5CDS-5UTR | ENST00000540149 | ENST00000268797 | ATP6V0D1 | chr16 | 67514860 | - | GFOD2 | chr16 | 67719705 | - |
| intron-5UTR | ENST00000602876 | ENST00000602377 | ATP6V0D1 | chr16 | 67514860 | - | GFOD2 | chr16 | 67719705 | - |
| intron-5UTR | ENST00000602876 | ENST00000268797 | ATP6V0D1 | chr16 | 67514860 | - | GFOD2 | chr16 | 67719705 | - |
| intron-5UTR | ENST00000567694 | ENST00000602377 | ATP6V0D1 | chr16 | 67514860 | - | GFOD2 | chr16 | 67719705 | - |
| intron-5UTR | ENST00000567694 | ENST00000268797 | ATP6V0D1 | chr16 | 67514860 | - | GFOD2 | chr16 | 67719705 | - |
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FusionProtFeatures for ATP6V0D1_GFOD2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ATP6V0D1 | GFOD2 |