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Fusion gene ID: 34339 |
FusionGeneSummary for SLC34A2_NDUFV1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SLC34A2_NDUFV1 | Fusion gene ID: 34339 | Hgene | Tgene | Gene symbol | SLC34A2 | NDUFV1 | Gene ID | 10568 | 4723 |
| Gene name | solute carrier family 34 member 2 | NADH:ubiquinone oxidoreductase core subunit V1 | |
| Synonyms | NAPI-3B|NAPI-IIb|NPTIIb | CI-51K|CI51KD|UQOR1 | |
| Cytomap | 4p15.2 | 11q13.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | sodium-dependent phosphate transport protein 2Bsodium/phosphate cotransporter 2Bsolute carrier family 34 (sodium phosphate), member 2solute carrier family 34 (type II sodium/phosphate cotransporter), member 2type II sodium-dependent phosphate transpor | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrialNADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDaNADH-ubiquinone oxidoreductase 51 kDa subunitcomplex I 51 kda subunitcomplex I 51kDa subunitcomplex I, mitochondrial respiratory chainm | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | O95436 | P49821 | |
| Ensembl transtripts involved in fusion gene | ENST00000504570, ENST00000382051, ENST00000503434, ENST00000510033, | ENST00000322776, ENST00000532303, ENST00000529927, ENST00000415352, ENST00000526169, | |
| Fusion gene scores | * DoF score | 6 X 5 X 3=90 | 35 X 6 X 14=2940 |
| # samples | 11 | 37 | |
| ** MAII score | log2(11/90*10)=0.289506617194985 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(37/2940*10)=-2.99021897920741 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SLC34A2 [Title/Abstract] AND NDUFV1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | SLC34A2 | GO:0006817 | phosphate ion transport | 10329428|10610722|12488042 |
| Hgene | SLC34A2 | GO:0030643 | cellular phosphate ion homeostasis | 10610722 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LUAD | TCGA-05-4405-01A | SLC34A2 | chr4 | 25680370 | + | NDUFV1 | chr11 | 67375697 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-intron | ENST00000504570 | ENST00000322776 | SLC34A2 | chr4 | 25680370 | + | NDUFV1 | chr11 | 67375697 | + |
| intron-intron | ENST00000504570 | ENST00000532303 | SLC34A2 | chr4 | 25680370 | + | NDUFV1 | chr11 | 67375697 | + |
| intron-intron | ENST00000504570 | ENST00000529927 | SLC34A2 | chr4 | 25680370 | + | NDUFV1 | chr11 | 67375697 | + |
| intron-intron | ENST00000504570 | ENST00000415352 | SLC34A2 | chr4 | 25680370 | + | NDUFV1 | chr11 | 67375697 | + |
| intron-intron | ENST00000504570 | ENST00000526169 | SLC34A2 | chr4 | 25680370 | + | NDUFV1 | chr11 | 67375697 | + |
| 5CDS-intron | ENST00000382051 | ENST00000322776 | SLC34A2 | chr4 | 25680370 | + | NDUFV1 | chr11 | 67375697 | + |
| 5CDS-intron | ENST00000382051 | ENST00000532303 | SLC34A2 | chr4 | 25680370 | + | NDUFV1 | chr11 | 67375697 | + |
| 5CDS-intron | ENST00000382051 | ENST00000529927 | SLC34A2 | chr4 | 25680370 | + | NDUFV1 | chr11 | 67375697 | + |
| 5CDS-intron | ENST00000382051 | ENST00000415352 | SLC34A2 | chr4 | 25680370 | + | NDUFV1 | chr11 | 67375697 | + |
| 5CDS-intron | ENST00000382051 | ENST00000526169 | SLC34A2 | chr4 | 25680370 | + | NDUFV1 | chr11 | 67375697 | + |
| intron-intron | ENST00000503434 | ENST00000322776 | SLC34A2 | chr4 | 25680370 | + | NDUFV1 | chr11 | 67375697 | + |
| intron-intron | ENST00000503434 | ENST00000532303 | SLC34A2 | chr4 | 25680370 | + | NDUFV1 | chr11 | 67375697 | + |
| intron-intron | ENST00000503434 | ENST00000529927 | SLC34A2 | chr4 | 25680370 | + | NDUFV1 | chr11 | 67375697 | + |
| intron-intron | ENST00000503434 | ENST00000415352 | SLC34A2 | chr4 | 25680370 | + | NDUFV1 | chr11 | 67375697 | + |
| intron-intron | ENST00000503434 | ENST00000526169 | SLC34A2 | chr4 | 25680370 | + | NDUFV1 | chr11 | 67375697 | + |
| intron-intron | ENST00000510033 | ENST00000322776 | SLC34A2 | chr4 | 25680370 | + | NDUFV1 | chr11 | 67375697 | + |
| intron-intron | ENST00000510033 | ENST00000532303 | SLC34A2 | chr4 | 25680370 | + | NDUFV1 | chr11 | 67375697 | + |
| intron-intron | ENST00000510033 | ENST00000529927 | SLC34A2 | chr4 | 25680370 | + | NDUFV1 | chr11 | 67375697 | + |
| intron-intron | ENST00000510033 | ENST00000415352 | SLC34A2 | chr4 | 25680370 | + | NDUFV1 | chr11 | 67375697 | + |
| intron-intron | ENST00000510033 | ENST00000526169 | SLC34A2 | chr4 | 25680370 | + | NDUFV1 | chr11 | 67375697 | + |
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FusionProtFeatures for SLC34A2_NDUFV1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SLC34A2 | NDUFV1 |