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Fusion gene ID: 34288 |
FusionGeneSummary for SLC2A10_ACSS2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SLC2A10_ACSS2 | Fusion gene ID: 34288 | Hgene | Tgene | Gene symbol | SLC2A10 | ACSS2 | Gene ID | 81031 | 55902 |
| Gene name | solute carrier family 2 member 10 | acyl-CoA synthetase short chain family member 2 | |
| Synonyms | ATS|GLUT10 | ACAS2|ACECS|ACS|ACSA|dJ1161H23.1 | |
| Cytomap | 20q13.12 | 20q11.22 | |
| Type of gene | protein-coding | protein-coding | |
| Description | solute carrier family 2, facilitated glucose transporter member 10GLUT-10glucose transporter type 10solute carrier family 2 (facilitated glucose transporter), member 10 | acetyl-coenzyme A synthetase, cytoplasmicacetate thiokinaseacetate-CoA ligaseacetyl-Coenzyme A synthetase 2 (ADP forming)acyl-activating enzymecytoplasmic acetyl-coenzyme A synthetase | |
| Modification date | 20180523 | 20180522 | |
| UniProtAcc | O95528 | Q9NR19 | |
| Ensembl transtripts involved in fusion gene | ENST00000359271, ENST00000486000, | ENST00000336325, ENST00000360596, ENST00000253382, ENST00000476922, | |
| Fusion gene scores | * DoF score | 3 X 3 X 2=18 | 5 X 3 X 3=45 |
| # samples | 3 | 5 | |
| ** MAII score | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(5/45*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: SLC2A10 [Title/Abstract] AND ACSS2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LUSC | TCGA-85-8664-01A | SLC2A10 | chr20 | 45338379 | + | ACSS2 | chr20 | 33500899 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000359271 | ENST00000336325 | SLC2A10 | chr20 | 45338379 | + | ACSS2 | chr20 | 33500899 | + |
| Frame-shift | ENST00000359271 | ENST00000360596 | SLC2A10 | chr20 | 45338379 | + | ACSS2 | chr20 | 33500899 | + |
| Frame-shift | ENST00000359271 | ENST00000253382 | SLC2A10 | chr20 | 45338379 | + | ACSS2 | chr20 | 33500899 | + |
| 5CDS-intron | ENST00000359271 | ENST00000476922 | SLC2A10 | chr20 | 45338379 | + | ACSS2 | chr20 | 33500899 | + |
| 3UTR-3CDS | ENST00000486000 | ENST00000336325 | SLC2A10 | chr20 | 45338379 | + | ACSS2 | chr20 | 33500899 | + |
| 3UTR-3CDS | ENST00000486000 | ENST00000360596 | SLC2A10 | chr20 | 45338379 | + | ACSS2 | chr20 | 33500899 | + |
| 3UTR-3CDS | ENST00000486000 | ENST00000253382 | SLC2A10 | chr20 | 45338379 | + | ACSS2 | chr20 | 33500899 | + |
| 3UTR-intron | ENST00000486000 | ENST00000476922 | SLC2A10 | chr20 | 45338379 | + | ACSS2 | chr20 | 33500899 | + |
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FusionProtFeatures for SLC2A10_ACSS2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SLC2A10 | ACSS2 |