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Fusion gene ID: 34261 |
FusionGeneSummary for SLC25A4_POGZ |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SLC25A4_POGZ | Fusion gene ID: 34261 | Hgene | Tgene | Gene symbol | SLC25A4 | POGZ | Gene ID | 291 | 23126 |
| Gene name | solute carrier family 25 member 4 | pogo transposable element derived with ZNF domain | |
| Synonyms | AAC1|ANT|ANT 1|ANT1|MTDPS12|MTDPS12A|PEO2|PEO3|PEOA2|T1 | MRD37|WHSUS|ZNF280E|ZNF635|ZNF635m | |
| Cytomap | 4q35.1 | 1q21.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ADP/ATP translocase 1ADP,ATP carrier protein 1ADP,ATP carrier protein, heart/skeletal muscleadenine nucleotide translocator 1 (skeletal muscle)heart/skeletal muscle ATP/ADP translocatorsolute carrier family 25 (mitochondrial carrier; adenine nucleoti | pogo transposable element with ZNF domainputative protein product of Nbla00003zinc finger protein 280Ezinc finger protein 635 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | P12235 | Q7Z3K3 | |
| Ensembl transtripts involved in fusion gene | ENST00000281456, | ENST00000392723, ENST00000361398, ENST00000271715, ENST00000368863, ENST00000409503, ENST00000531094, ENST00000540984, ENST00000491586, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 4 X 3 X 3=36 |
| # samples | 1 | 4 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(4/36*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: SLC25A4 [Title/Abstract] AND POGZ [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | N45527 | SLC25A4 | chr4 | 186068790 | + | POGZ | chr1 | 151418993 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-intron | ENST00000281456 | ENST00000392723 | SLC25A4 | chr4 | 186068790 | + | POGZ | chr1 | 151418993 | - |
| 3UTR-intron | ENST00000281456 | ENST00000361398 | SLC25A4 | chr4 | 186068790 | + | POGZ | chr1 | 151418993 | - |
| 3UTR-intron | ENST00000281456 | ENST00000271715 | SLC25A4 | chr4 | 186068790 | + | POGZ | chr1 | 151418993 | - |
| 3UTR-intron | ENST00000281456 | ENST00000368863 | SLC25A4 | chr4 | 186068790 | + | POGZ | chr1 | 151418993 | - |
| 3UTR-intron | ENST00000281456 | ENST00000409503 | SLC25A4 | chr4 | 186068790 | + | POGZ | chr1 | 151418993 | - |
| 3UTR-intron | ENST00000281456 | ENST00000531094 | SLC25A4 | chr4 | 186068790 | + | POGZ | chr1 | 151418993 | - |
| 3UTR-intron | ENST00000281456 | ENST00000540984 | SLC25A4 | chr4 | 186068790 | + | POGZ | chr1 | 151418993 | - |
| 3UTR-intron | ENST00000281456 | ENST00000491586 | SLC25A4 | chr4 | 186068790 | + | POGZ | chr1 | 151418993 | - |
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FusionProtFeatures for SLC25A4_POGZ |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SLC25A4 | POGZ |