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Fusion gene ID: 34205 |
FusionGeneSummary for SLC25A23_SLC2A9 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SLC25A23_SLC2A9 | Fusion gene ID: 34205 | Hgene | Tgene | Gene symbol | SLC25A23 | SLC2A9 | Gene ID | 79085 | 56606 |
| Gene name | solute carrier family 25 member 23 | solute carrier family 2 member 9 | |
| Synonyms | APC2|MCSC2|SCaMC-3 | GLUT9|GLUTX|UAQTL2|URATv1 | |
| Cytomap | 19p13.3 | 4p16.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | calcium-binding mitochondrial carrier protein SCaMC-3mitochondrial ATP-Mg/Pi carrier protein 2mitochondrial Ca(2+)-dependent solute carrier protein 2mitochondrial Ca2+-dependent solute carrier protein 2short calcium-binding mitochondrial carrier 3sma | solute carrier family 2, facilitated glucose transporter member 9GLUT-9glucose transporter type 9human glucose transporter-like protein-9solute carrier family 2 (facilitated glucose transporter), member 9urate voltage-driven efflux transporter 1 | |
| Modification date | 20180523 | 20180527 | |
| UniProtAcc | Q9BV35 | Q9NRM0 | |
| Ensembl transtripts involved in fusion gene | ENST00000601760, ENST00000301454, ENST00000414491, ENST00000334510, | ENST00000264784, ENST00000506583, ENST00000309065, ENST00000481042, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 3 X 3 X 2=18 |
| # samples | 1 | 3 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: SLC25A23 [Title/Abstract] AND SLC2A9 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-B6-A0RT-01A | SLC25A23 | chr19 | 6456431 | - | SLC2A9 | chr4 | 9772993 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-intron | ENST00000601760 | ENST00000264784 | SLC25A23 | chr19 | 6456431 | - | SLC2A9 | chr4 | 9772993 | - |
| intron-intron | ENST00000601760 | ENST00000506583 | SLC25A23 | chr19 | 6456431 | - | SLC2A9 | chr4 | 9772993 | - |
| intron-intron | ENST00000601760 | ENST00000309065 | SLC25A23 | chr19 | 6456431 | - | SLC2A9 | chr4 | 9772993 | - |
| intron-intron | ENST00000601760 | ENST00000481042 | SLC25A23 | chr19 | 6456431 | - | SLC2A9 | chr4 | 9772993 | - |
| 5CDS-intron | ENST00000301454 | ENST00000264784 | SLC25A23 | chr19 | 6456431 | - | SLC2A9 | chr4 | 9772993 | - |
| 5CDS-intron | ENST00000301454 | ENST00000506583 | SLC25A23 | chr19 | 6456431 | - | SLC2A9 | chr4 | 9772993 | - |
| 5CDS-intron | ENST00000301454 | ENST00000309065 | SLC25A23 | chr19 | 6456431 | - | SLC2A9 | chr4 | 9772993 | - |
| 5CDS-intron | ENST00000301454 | ENST00000481042 | SLC25A23 | chr19 | 6456431 | - | SLC2A9 | chr4 | 9772993 | - |
| intron-intron | ENST00000414491 | ENST00000264784 | SLC25A23 | chr19 | 6456431 | - | SLC2A9 | chr4 | 9772993 | - |
| intron-intron | ENST00000414491 | ENST00000506583 | SLC25A23 | chr19 | 6456431 | - | SLC2A9 | chr4 | 9772993 | - |
| intron-intron | ENST00000414491 | ENST00000309065 | SLC25A23 | chr19 | 6456431 | - | SLC2A9 | chr4 | 9772993 | - |
| intron-intron | ENST00000414491 | ENST00000481042 | SLC25A23 | chr19 | 6456431 | - | SLC2A9 | chr4 | 9772993 | - |
| 5CDS-intron | ENST00000334510 | ENST00000264784 | SLC25A23 | chr19 | 6456431 | - | SLC2A9 | chr4 | 9772993 | - |
| 5CDS-intron | ENST00000334510 | ENST00000506583 | SLC25A23 | chr19 | 6456431 | - | SLC2A9 | chr4 | 9772993 | - |
| 5CDS-intron | ENST00000334510 | ENST00000309065 | SLC25A23 | chr19 | 6456431 | - | SLC2A9 | chr4 | 9772993 | - |
| 5CDS-intron | ENST00000334510 | ENST00000481042 | SLC25A23 | chr19 | 6456431 | - | SLC2A9 | chr4 | 9772993 | - |
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FusionProtFeatures for SLC25A23_SLC2A9 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SLC25A23 | SLC2A9 |