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Fusion gene ID: 34110 |
FusionGeneSummary for SLC1A3_FYB |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SLC1A3_FYB | Fusion gene ID: 34110 | Hgene | Tgene | Gene symbol | SLC1A3 | FYB | Gene ID | 6507 |
| Gene name | solute carrier family 1 member 3 | ||
| Synonyms | EA6|EAAT1|GLAST|GLAST1 | ||
| Cytomap | 5p13.2 | ||
| Type of gene | protein-coding | ||
| Description | excitatory amino acid transporter 1GLAST-1sodium-dependent glutamate/aspartate transporter 1solute carrier family 1 (glial high affinity glutamate transporter), member 3 | ||
| Modification date | 20180519 | ||
| UniProtAcc | P43003 | ||
| Ensembl transtripts involved in fusion gene | ENST00000265113, ENST00000506725, ENST00000381918, | ENST00000351578, ENST00000515010, ENST00000505428, ENST00000512982, ENST00000540520, ENST00000503065, | |
| Fusion gene scores | * DoF score | 11 X 9 X 6=594 | 7 X 7 X 5=245 |
| # samples | 12 | 8 | |
| ** MAII score | log2(12/594*10)=-2.30742852519225 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(8/245*10)=-1.61470984411521 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SLC1A3 [Title/Abstract] AND FYB [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | SLC1A3 | GO:0015813 | L-glutamate transmembrane transport | 26690923 |
| Hgene | SLC1A3 | GO:0051938 | L-glutamate import | 7521911 |
| Hgene | SLC1A3 | GO:0070779 | D-aspartate import across plasma membrane | 7521911 |
| Hgene | SLC1A3 | GO:0071805 | potassium ion transmembrane transport | 20477940 |
| Hgene | SLC1A3 | GO:0098712 | L-glutamate import across plasma membrane | 26690923 |
| Hgene | SLC1A3 | GO:0140009 | L-aspartate import across plasma membrane | 20477940 |
| Hgene | SLC1A3 | GO:1902476 | chloride transmembrane transport | 20477940 |