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Fusion gene ID: 34006 |
FusionGeneSummary for SLAIN2_CWH43 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SLAIN2_CWH43 | Fusion gene ID: 34006 | Hgene | Tgene | Gene symbol | SLAIN2 | CWH43 | Gene ID | 57606 | 80157 |
| Gene name | SLAIN motif family member 2 | cell wall biogenesis 43 C-terminal homolog | |
| Synonyms | KIAA1458 | CWH43-C|PGAP2IP | |
| Cytomap | 4p11 | 4p11 | |
| Type of gene | protein-coding | protein-coding | |
| Description | SLAIN motif-containing protein 2 | PGAP2-interacting proteincell wall biogenesis protein 43 C-terminal homolog | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q9P270 | Q9H720 | |
| Ensembl transtripts involved in fusion gene | ENST00000264313, ENST00000506375, ENST00000512093, | ENST00000226432, ENST00000513409, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 3 X 3 X 3=27 |
| # samples | 1 | 3 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: SLAIN2 [Title/Abstract] AND CWH43 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | HNSC | TCGA-CN-4725-01A | SLAIN2 | chr4 | 48385801 | + | CWH43 | chr4 | 49005752 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000264313 | ENST00000226432 | SLAIN2 | chr4 | 48385801 | + | CWH43 | chr4 | 49005752 | + |
| In-frame | ENST00000264313 | ENST00000513409 | SLAIN2 | chr4 | 48385801 | + | CWH43 | chr4 | 49005752 | + |
| intron-3CDS | ENST00000506375 | ENST00000226432 | SLAIN2 | chr4 | 48385801 | + | CWH43 | chr4 | 49005752 | + |
| intron-3CDS | ENST00000506375 | ENST00000513409 | SLAIN2 | chr4 | 48385801 | + | CWH43 | chr4 | 49005752 | + |
| In-frame | ENST00000512093 | ENST00000226432 | SLAIN2 | chr4 | 48385801 | + | CWH43 | chr4 | 49005752 | + |
| In-frame | ENST00000512093 | ENST00000513409 | SLAIN2 | chr4 | 48385801 | + | CWH43 | chr4 | 49005752 | + |
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FusionProtFeatures for SLAIN2_CWH43 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SLAIN2 | CWH43 |