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Fusion gene ID: 33580 |
FusionGeneSummary for SGOL2_FBXO8 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SGOL2_FBXO8 | Fusion gene ID: 33580 | Hgene | Tgene | Gene symbol | SGOL2 | FBXO8 | Gene ID | 151246 | 26269 |
| Gene name | shugoshin 2 | F-box protein 8 | |
| Synonyms | SGOL2|TRIPIN | DC10|FBS|FBX8 | |
| Cytomap | 2q33.1 | 4q34.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | shugoshin 2shugoshin-like 2 | F-box only protein 8F-box protein Fbx8F-box/SEC7 protein FBS | |
| Modification date | 20180522 | 20180519 | |
| UniProtAcc | Q9NRD0 | ||
| Ensembl transtripts involved in fusion gene | ENST00000357799, ENST00000409203, ENST00000469840, | ENST00000393674, ENST00000503293, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 1 X 1 X 1=1 |
| # samples | 1 | 1 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: SGOL2 [Title/Abstract] AND FBXO8 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | PRAD | TCGA-YL-A8SC-01A | SGOL2 | chr2 | 201390975 | + | FBXO8 | chr4 | 175184251 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5UTR-5UTR | ENST00000357799 | ENST00000393674 | SGOL2 | chr2 | 201390975 | + | FBXO8 | chr4 | 175184251 | - |
| 5UTR-5UTR | ENST00000357799 | ENST00000503293 | SGOL2 | chr2 | 201390975 | + | FBXO8 | chr4 | 175184251 | - |
| 5UTR-5UTR | ENST00000409203 | ENST00000393674 | SGOL2 | chr2 | 201390975 | + | FBXO8 | chr4 | 175184251 | - |
| 5UTR-5UTR | ENST00000409203 | ENST00000503293 | SGOL2 | chr2 | 201390975 | + | FBXO8 | chr4 | 175184251 | - |
| intron-5UTR | ENST00000469840 | ENST00000393674 | SGOL2 | chr2 | 201390975 | + | FBXO8 | chr4 | 175184251 | - |
| intron-5UTR | ENST00000469840 | ENST00000503293 | SGOL2 | chr2 | 201390975 | + | FBXO8 | chr4 | 175184251 | - |
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FusionProtFeatures for SGOL2_FBXO8 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SGOL2 | FBXO8 |