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Fusion gene ID: 3342 |
FusionGeneSummary for ATP2B1_CORO1C |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ATP2B1_CORO1C | Fusion gene ID: 3342 | Hgene | Tgene | Gene symbol | ATP2B1 | CORO1C | Gene ID | 490 | 23603 |
| Gene name | ATPase plasma membrane Ca2+ transporting 1 | coronin 1C | |
| Synonyms | PMCA1|PMCA1kb | HCRNN4 | |
| Cytomap | 12q21.33 | 12q24.11 | |
| Type of gene | protein-coding | protein-coding | |
| Description | plasma membrane calcium-transporting ATPase 1ATPase, Ca++ transporting, plasma membrane 1plasma membrane calcium pump | coronin-1Ccoronin, actin binding protein, 1Ccoronin-3 | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | P20020 | Q9ULV4 | |
| Ensembl transtripts involved in fusion gene | ENST00000348959, ENST00000261173, ENST00000359142, ENST00000428670, ENST00000393164, | ENST00000261401, ENST00000541050, ENST00000549384, ENST00000421578, ENST00000420959, ENST00000549772, | |
| Fusion gene scores | * DoF score | 13 X 9 X 6=702 | 8 X 6 X 5=240 |
| # samples | 10 | 8 | |
| ** MAII score | log2(10/702*10)=-2.81147103052984 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(8/240*10)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ATP2B1 [Title/Abstract] AND CORO1C [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | ATP2B1 | GO:0051480 | regulation of cytosolic calcium ion concentration | 18029012 |
| Hgene | ATP2B1 | GO:1990034 | calcium ion export across plasma membrane | 18029012 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SARC | TCGA-3B-A9HO-01A | ATP2B1 | chr12 | 90102996 | - | CORO1C | chr12 | 109095099 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-5UTR | ENST00000348959 | ENST00000261401 | ATP2B1 | chr12 | 90102996 | - | CORO1C | chr12 | 109095099 | - |
| intron-5UTR | ENST00000348959 | ENST00000541050 | ATP2B1 | chr12 | 90102996 | - | CORO1C | chr12 | 109095099 | - |
| intron-5UTR | ENST00000348959 | ENST00000549384 | ATP2B1 | chr12 | 90102996 | - | CORO1C | chr12 | 109095099 | - |
| intron-intron | ENST00000348959 | ENST00000421578 | ATP2B1 | chr12 | 90102996 | - | CORO1C | chr12 | 109095099 | - |
| intron-intron | ENST00000348959 | ENST00000420959 | ATP2B1 | chr12 | 90102996 | - | CORO1C | chr12 | 109095099 | - |
| intron-intron | ENST00000348959 | ENST00000549772 | ATP2B1 | chr12 | 90102996 | - | CORO1C | chr12 | 109095099 | - |
| intron-5UTR | ENST00000261173 | ENST00000261401 | ATP2B1 | chr12 | 90102996 | - | CORO1C | chr12 | 109095099 | - |
| intron-5UTR | ENST00000261173 | ENST00000541050 | ATP2B1 | chr12 | 90102996 | - | CORO1C | chr12 | 109095099 | - |
| intron-5UTR | ENST00000261173 | ENST00000549384 | ATP2B1 | chr12 | 90102996 | - | CORO1C | chr12 | 109095099 | - |
| intron-intron | ENST00000261173 | ENST00000421578 | ATP2B1 | chr12 | 90102996 | - | CORO1C | chr12 | 109095099 | - |
| intron-intron | ENST00000261173 | ENST00000420959 | ATP2B1 | chr12 | 90102996 | - | CORO1C | chr12 | 109095099 | - |
| intron-intron | ENST00000261173 | ENST00000549772 | ATP2B1 | chr12 | 90102996 | - | CORO1C | chr12 | 109095099 | - |
| intron-5UTR | ENST00000359142 | ENST00000261401 | ATP2B1 | chr12 | 90102996 | - | CORO1C | chr12 | 109095099 | - |
| intron-5UTR | ENST00000359142 | ENST00000541050 | ATP2B1 | chr12 | 90102996 | - | CORO1C | chr12 | 109095099 | - |
| intron-5UTR | ENST00000359142 | ENST00000549384 | ATP2B1 | chr12 | 90102996 | - | CORO1C | chr12 | 109095099 | - |
| intron-intron | ENST00000359142 | ENST00000421578 | ATP2B1 | chr12 | 90102996 | - | CORO1C | chr12 | 109095099 | - |
| intron-intron | ENST00000359142 | ENST00000420959 | ATP2B1 | chr12 | 90102996 | - | CORO1C | chr12 | 109095099 | - |
| intron-intron | ENST00000359142 | ENST00000549772 | ATP2B1 | chr12 | 90102996 | - | CORO1C | chr12 | 109095099 | - |
| intron-5UTR | ENST00000428670 | ENST00000261401 | ATP2B1 | chr12 | 90102996 | - | CORO1C | chr12 | 109095099 | - |
| intron-5UTR | ENST00000428670 | ENST00000541050 | ATP2B1 | chr12 | 90102996 | - | CORO1C | chr12 | 109095099 | - |
| intron-5UTR | ENST00000428670 | ENST00000549384 | ATP2B1 | chr12 | 90102996 | - | CORO1C | chr12 | 109095099 | - |
| intron-intron | ENST00000428670 | ENST00000421578 | ATP2B1 | chr12 | 90102996 | - | CORO1C | chr12 | 109095099 | - |
| intron-intron | ENST00000428670 | ENST00000420959 | ATP2B1 | chr12 | 90102996 | - | CORO1C | chr12 | 109095099 | - |
| intron-intron | ENST00000428670 | ENST00000549772 | ATP2B1 | chr12 | 90102996 | - | CORO1C | chr12 | 109095099 | - |
| intron-5UTR | ENST00000393164 | ENST00000261401 | ATP2B1 | chr12 | 90102996 | - | CORO1C | chr12 | 109095099 | - |
| intron-5UTR | ENST00000393164 | ENST00000541050 | ATP2B1 | chr12 | 90102996 | - | CORO1C | chr12 | 109095099 | - |
| intron-5UTR | ENST00000393164 | ENST00000549384 | ATP2B1 | chr12 | 90102996 | - | CORO1C | chr12 | 109095099 | - |
| intron-intron | ENST00000393164 | ENST00000421578 | ATP2B1 | chr12 | 90102996 | - | CORO1C | chr12 | 109095099 | - |
| intron-intron | ENST00000393164 | ENST00000420959 | ATP2B1 | chr12 | 90102996 | - | CORO1C | chr12 | 109095099 | - |
| intron-intron | ENST00000393164 | ENST00000549772 | ATP2B1 | chr12 | 90102996 | - | CORO1C | chr12 | 109095099 | - |
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FusionProtFeatures for ATP2B1_CORO1C |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ATP2B1 | CORO1C |