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Fusion gene ID: 33241 |
FusionGeneSummary for SERINC1_PALLD |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SERINC1_PALLD | Fusion gene ID: 33241 | Hgene | Tgene | Gene symbol | SERINC1 | PALLD | Gene ID | 57515 | 23022 |
| Gene name | serine incorporator 1 | palladin, cytoskeletal associated protein | |
| Synonyms | TDE1L|TDE2|TMS-2|TMS2 | CGI-151|CGI151|MYN|PNCA1|SIH002 | |
| Cytomap | 6q22.31 | 4q32.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | serine incorporator 1tumor differentially expressed protein 2 | palladinmyoneurinsarcoma antigen NY-SAR-77 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q9NRX5 | Q8WX93 | |
| Ensembl transtripts involved in fusion gene | ENST00000339697, | ENST00000335742, ENST00000261509, ENST00000505667, ENST00000333488, ENST00000512127, ENST00000507735, | |
| Fusion gene scores | * DoF score | 5 X 7 X 2=70 | 7 X 6 X 3=126 |
| # samples | 7 | 7 | |
| ** MAII score | log2(7/70*10)=0 | log2(7/126*10)=-0.84799690655495 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SERINC1 [Title/Abstract] AND PALLD [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | AA425614 | SERINC1 | chr6 | 122765520 | - | PALLD | chr4 | 169847900 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3UTR | ENST00000339697 | ENST00000335742 | SERINC1 | chr6 | 122765520 | - | PALLD | chr4 | 169847900 | + |
| intron-3UTR | ENST00000339697 | ENST00000261509 | SERINC1 | chr6 | 122765520 | - | PALLD | chr4 | 169847900 | + |
| intron-intron | ENST00000339697 | ENST00000505667 | SERINC1 | chr6 | 122765520 | - | PALLD | chr4 | 169847900 | + |
| intron-intron | ENST00000339697 | ENST00000333488 | SERINC1 | chr6 | 122765520 | - | PALLD | chr4 | 169847900 | + |
| intron-intron | ENST00000339697 | ENST00000512127 | SERINC1 | chr6 | 122765520 | - | PALLD | chr4 | 169847900 | + |
| intron-3UTR | ENST00000339697 | ENST00000507735 | SERINC1 | chr6 | 122765520 | - | PALLD | chr4 | 169847900 | + |
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FusionProtFeatures for SERINC1_PALLD |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SERINC1 | PALLD |