|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 33140 |
FusionGeneSummary for SEMA3D_RBM28 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SEMA3D_RBM28 | Fusion gene ID: 33140 | Hgene | Tgene | Gene symbol | SEMA3D | RBM28 | Gene ID | 223117 | 55131 |
| Gene name | semaphorin 3D | RNA binding motif protein 28 | |
| Synonyms | Sema-Z2|coll-2 | ANES | |
| Cytomap | 7q21.11 | 7q32.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | semaphorin-3Dcollapsin 2sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | RNA-binding protein 282810480G15Rik | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | O95025 | Q9NW13 | |
| Ensembl transtripts involved in fusion gene | ENST00000284136, ENST00000444867, ENST00000484038, | ENST00000223073, ENST00000481788, ENST00000415472, | |
| Fusion gene scores | * DoF score | 2 X 3 X 2=12 | 3 X 3 X 3=27 |
| # samples | 2 | 3 | |
| ** MAII score | log2(2/12*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: SEMA3D [Title/Abstract] AND RBM28 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | PRAD | TCGA-CH-5788-01A | SEMA3D | chr7 | 84782924 | - | RBM28 | chr7 | 127979845 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000284136 | ENST00000223073 | SEMA3D | chr7 | 84782924 | - | RBM28 | chr7 | 127979845 | - |
| intron-intron | ENST00000284136 | ENST00000481788 | SEMA3D | chr7 | 84782924 | - | RBM28 | chr7 | 127979845 | - |
| intron-intron | ENST00000284136 | ENST00000415472 | SEMA3D | chr7 | 84782924 | - | RBM28 | chr7 | 127979845 | - |
| 5UTR-3CDS | ENST00000444867 | ENST00000223073 | SEMA3D | chr7 | 84782924 | - | RBM28 | chr7 | 127979845 | - |
| 5UTR-intron | ENST00000444867 | ENST00000481788 | SEMA3D | chr7 | 84782924 | - | RBM28 | chr7 | 127979845 | - |
| 5UTR-intron | ENST00000444867 | ENST00000415472 | SEMA3D | chr7 | 84782924 | - | RBM28 | chr7 | 127979845 | - |
| intron-3CDS | ENST00000484038 | ENST00000223073 | SEMA3D | chr7 | 84782924 | - | RBM28 | chr7 | 127979845 | - |
| intron-intron | ENST00000484038 | ENST00000481788 | SEMA3D | chr7 | 84782924 | - | RBM28 | chr7 | 127979845 | - |
| intron-intron | ENST00000484038 | ENST00000415472 | SEMA3D | chr7 | 84782924 | - | RBM28 | chr7 | 127979845 | - |
Top |
FusionProtFeatures for SEMA3D_RBM28 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SEMA3D | RBM28 |