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Fusion gene ID: 33109 |
FusionGeneSummary for SECISBP2_SECISBP2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SECISBP2_SECISBP2 | Fusion gene ID: 33109 | Hgene | Tgene | Gene symbol | SECISBP2 | SECISBP2 | Gene ID | 79048 | 79048 |
| Gene name | SECIS binding protein 2 | SECIS binding protein 2 | |
| Synonyms | SBP2 | SBP2 | |
| Cytomap | 9q22.2 | 9q22.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | selenocysteine insertion sequence-binding protein 2Sec insertion sequence-binding protein 2 | selenocysteine insertion sequence-binding protein 2Sec insertion sequence-binding protein 2 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q96T21 | Q96T21 | |
| Ensembl transtripts involved in fusion gene | ENST00000375807, ENST00000339901, ENST00000534113, ENST00000470305, | ENST00000375807, ENST00000339901, ENST00000534113, ENST00000470305, | |
| Fusion gene scores | * DoF score | 5 X 6 X 2=60 | 4 X 4 X 2=32 |
| # samples | 6 | 6 | |
| ** MAII score | log2(6/60*10)=0 | log2(6/32*10)=0.906890595608518 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: SECISBP2 [Title/Abstract] AND SECISBP2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | AU253387 | SECISBP2 | chr9 | 91949494 | - | SECISBP2 | chr9 | 91954864 | - | ||
| ChiTaRS3.1 | CV416238 | SECISBP2 | chr9 | 91939671 | + | SECISBP2 | chr9 | 91939346 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000375807 | ENST00000375807 | SECISBP2 | chr9 | 91949494 | - | SECISBP2 | chr9 | 91954864 | - |
| 5CDS-intron | ENST00000375807 | ENST00000339901 | SECISBP2 | chr9 | 91949494 | - | SECISBP2 | chr9 | 91954864 | - |
| 5CDS-intron | ENST00000375807 | ENST00000534113 | SECISBP2 | chr9 | 91949494 | - | SECISBP2 | chr9 | 91954864 | - |
| 5CDS-intron | ENST00000375807 | ENST00000470305 | SECISBP2 | chr9 | 91949494 | - | SECISBP2 | chr9 | 91954864 | - |
| 5CDS-intron | ENST00000339901 | ENST00000375807 | SECISBP2 | chr9 | 91949494 | - | SECISBP2 | chr9 | 91954864 | - |
| 5CDS-intron | ENST00000339901 | ENST00000339901 | SECISBP2 | chr9 | 91949494 | - | SECISBP2 | chr9 | 91954864 | - |
| 5CDS-intron | ENST00000339901 | ENST00000534113 | SECISBP2 | chr9 | 91949494 | - | SECISBP2 | chr9 | 91954864 | - |
| 5CDS-intron | ENST00000339901 | ENST00000470305 | SECISBP2 | chr9 | 91949494 | - | SECISBP2 | chr9 | 91954864 | - |
| 5CDS-intron | ENST00000534113 | ENST00000375807 | SECISBP2 | chr9 | 91949494 | - | SECISBP2 | chr9 | 91954864 | - |
| 5CDS-intron | ENST00000534113 | ENST00000339901 | SECISBP2 | chr9 | 91949494 | - | SECISBP2 | chr9 | 91954864 | - |
| 5CDS-intron | ENST00000534113 | ENST00000534113 | SECISBP2 | chr9 | 91949494 | - | SECISBP2 | chr9 | 91954864 | - |
| 5CDS-intron | ENST00000534113 | ENST00000470305 | SECISBP2 | chr9 | 91949494 | - | SECISBP2 | chr9 | 91954864 | - |
| intron-intron | ENST00000470305 | ENST00000375807 | SECISBP2 | chr9 | 91949494 | - | SECISBP2 | chr9 | 91954864 | - |
| intron-intron | ENST00000470305 | ENST00000339901 | SECISBP2 | chr9 | 91949494 | - | SECISBP2 | chr9 | 91954864 | - |
| intron-intron | ENST00000470305 | ENST00000534113 | SECISBP2 | chr9 | 91949494 | - | SECISBP2 | chr9 | 91954864 | - |
| intron-intron | ENST00000470305 | ENST00000470305 | SECISBP2 | chr9 | 91949494 | - | SECISBP2 | chr9 | 91954864 | - |
| intron-intron | ENST00000375807 | ENST00000375807 | SECISBP2 | chr9 | 91939671 | + | SECISBP2 | chr9 | 91939346 | - |
| intron-intron | ENST00000375807 | ENST00000339901 | SECISBP2 | chr9 | 91939671 | + | SECISBP2 | chr9 | 91939346 | - |
| intron-intron | ENST00000375807 | ENST00000534113 | SECISBP2 | chr9 | 91939671 | + | SECISBP2 | chr9 | 91939346 | - |
| intron-3UTR | ENST00000375807 | ENST00000470305 | SECISBP2 | chr9 | 91939671 | + | SECISBP2 | chr9 | 91939346 | - |
| intron-intron | ENST00000339901 | ENST00000375807 | SECISBP2 | chr9 | 91939671 | + | SECISBP2 | chr9 | 91939346 | - |
| intron-intron | ENST00000339901 | ENST00000339901 | SECISBP2 | chr9 | 91939671 | + | SECISBP2 | chr9 | 91939346 | - |
| intron-intron | ENST00000339901 | ENST00000534113 | SECISBP2 | chr9 | 91939671 | + | SECISBP2 | chr9 | 91939346 | - |
| intron-3UTR | ENST00000339901 | ENST00000470305 | SECISBP2 | chr9 | 91939671 | + | SECISBP2 | chr9 | 91939346 | - |
| intron-intron | ENST00000534113 | ENST00000375807 | SECISBP2 | chr9 | 91939671 | + | SECISBP2 | chr9 | 91939346 | - |
| intron-intron | ENST00000534113 | ENST00000339901 | SECISBP2 | chr9 | 91939671 | + | SECISBP2 | chr9 | 91939346 | - |
| intron-intron | ENST00000534113 | ENST00000534113 | SECISBP2 | chr9 | 91939671 | + | SECISBP2 | chr9 | 91939346 | - |
| intron-3UTR | ENST00000534113 | ENST00000470305 | SECISBP2 | chr9 | 91939671 | + | SECISBP2 | chr9 | 91939346 | - |
| 3UTR-intron | ENST00000470305 | ENST00000375807 | SECISBP2 | chr9 | 91939671 | + | SECISBP2 | chr9 | 91939346 | - |
| 3UTR-intron | ENST00000470305 | ENST00000339901 | SECISBP2 | chr9 | 91939671 | + | SECISBP2 | chr9 | 91939346 | - |
| 3UTR-intron | ENST00000470305 | ENST00000534113 | SECISBP2 | chr9 | 91939671 | + | SECISBP2 | chr9 | 91939346 | - |
| 3UTR-3UTR | ENST00000470305 | ENST00000470305 | SECISBP2 | chr9 | 91939671 | + | SECISBP2 | chr9 | 91939346 | - |
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FusionProtFeatures for SECISBP2_SECISBP2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SECISBP2 | SECISBP2 |