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Fusion gene ID: 32770 |
FusionGeneSummary for SCAPER_CEP120 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SCAPER_CEP120 | Fusion gene ID: 32770 | Hgene | Tgene | Gene symbol | SCAPER | CEP120 | Gene ID | 49855 | 153241 |
| Gene name | S-phase cyclin A associated protein in the ER | centrosomal protein 120 | |
| Synonyms | MSTP063|ZNF291|Zfp291 | CCDC100|JBTS31|SRTD13 | |
| Cytomap | 15q24.3 | 5q23.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | S phase cyclin A-associated protein in the endoplasmic reticulumzinc finger protein 291 | centrosomal protein of 120 kDacentrosomal protein 120kDacoiled-coil domain-containing protein 100 | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | Q9BY12 | Q8N960 | |
| Ensembl transtripts involved in fusion gene | ENST00000538941, ENST00000563290, ENST00000324767, ENST00000562890, | ENST00000306467, ENST00000306481, ENST00000328236, ENST00000395431, ENST00000515110, | |
| Fusion gene scores | * DoF score | 7 X 6 X 7=294 | 1 X 1 X 1=1 |
| # samples | 7 | 1 | |
| ** MAII score | log2(7/294*10)=-2.0703893278914 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: SCAPER [Title/Abstract] AND CEP120 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | COAD | TCGA-AA-A02K-01A | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000538941 | ENST00000306467 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| intron-3CDS | ENST00000538941 | ENST00000306481 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| intron-3CDS | ENST00000538941 | ENST00000328236 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| intron-intron | ENST00000538941 | ENST00000395431 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| intron-intron | ENST00000538941 | ENST00000515110 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| Frame-shift | ENST00000563290 | ENST00000306467 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| Frame-shift | ENST00000563290 | ENST00000306481 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| Frame-shift | ENST00000563290 | ENST00000328236 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| 5CDS-intron | ENST00000563290 | ENST00000395431 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| 5CDS-intron | ENST00000563290 | ENST00000515110 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| In-frame | ENST00000324767 | ENST00000306467 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| In-frame | ENST00000324767 | ENST00000306481 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| In-frame | ENST00000324767 | ENST00000328236 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| 5CDS-intron | ENST00000324767 | ENST00000395431 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| 5CDS-intron | ENST00000324767 | ENST00000515110 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| intron-3CDS | ENST00000562890 | ENST00000306467 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| intron-3CDS | ENST00000562890 | ENST00000306481 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| intron-3CDS | ENST00000562890 | ENST00000328236 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| intron-intron | ENST00000562890 | ENST00000395431 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| intron-intron | ENST00000562890 | ENST00000515110 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
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FusionProtFeatures for SCAPER_CEP120 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SCAPER | CEP120 |