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Fusion gene ID: 32752 |
FusionGeneSummary for SCAMP1_ARSB |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SCAMP1_ARSB | Fusion gene ID: 32752 | Hgene | Tgene | Gene symbol | SCAMP1 | ARSB | Gene ID | 9522 | 411 |
| Gene name | secretory carrier membrane protein 1 | arylsulfatase B | |
| Synonyms | SCAMP|SCAMP37 | ASB|G4S|MPS6 | |
| Cytomap | 5q14.1 | 5q14.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | secretory carrier-associated membrane protein 1 | arylsulfatase BN-acetylgalactosamine-4-sulfatase | |
| Modification date | 20180523 | 20180522 | |
| UniProtAcc | P15848 | ||
| Ensembl transtripts involved in fusion gene | ENST00000538629, ENST00000339292, | ENST00000264914, ENST00000396151, ENST00000565165, ENST00000521800, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 5 X 3 X 4=60 |
| # samples | 1 | 4 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(4/60*10)=-0.584962500721156 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SCAMP1 [Title/Abstract] AND ARSB [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | SCAMP1 | GO:0015031 | protein transport | 15840657 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | STAD | TCGA-HF-A5NB-01A | SCAMP1 | chr5 | 77745857 | + | ARSB | chr5 | 78135249 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000538629 | ENST00000264914 | SCAMP1 | chr5 | 77745857 | + | ARSB | chr5 | 78135249 | - |
| Frame-shift | ENST00000538629 | ENST00000396151 | SCAMP1 | chr5 | 77745857 | + | ARSB | chr5 | 78135249 | - |
| Frame-shift | ENST00000538629 | ENST00000565165 | SCAMP1 | chr5 | 77745857 | + | ARSB | chr5 | 78135249 | - |
| 5CDS-intron | ENST00000538629 | ENST00000521800 | SCAMP1 | chr5 | 77745857 | + | ARSB | chr5 | 78135249 | - |
| 3UTR-3CDS | ENST00000339292 | ENST00000264914 | SCAMP1 | chr5 | 77745857 | + | ARSB | chr5 | 78135249 | - |
| 3UTR-3CDS | ENST00000339292 | ENST00000396151 | SCAMP1 | chr5 | 77745857 | + | ARSB | chr5 | 78135249 | - |
| 3UTR-3CDS | ENST00000339292 | ENST00000565165 | SCAMP1 | chr5 | 77745857 | + | ARSB | chr5 | 78135249 | - |
| 3UTR-intron | ENST00000339292 | ENST00000521800 | SCAMP1 | chr5 | 77745857 | + | ARSB | chr5 | 78135249 | - |
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FusionProtFeatures for SCAMP1_ARSB |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SCAMP1 | ARSB |