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Fusion gene ID: 32673 |
FusionGeneSummary for SAT1_CTTN |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SAT1_CTTN | Fusion gene ID: 32673 | Hgene | Tgene | Gene symbol | SAT1 | CTTN | Gene ID | 81539 | 2017 |
| Gene name | solute carrier family 38 member 1 | cortactin | |
| Synonyms | ATA1|NAT2|SAT1|SNAT1 | EMS1 | |
| Cytomap | 12q13.11 | 11q13.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | sodium-coupled neutral amino acid transporter 1N-system amino acid transporter 2amino acid transporter A1amino acid transporter system A1system A amino acid transporter 1system N amino acid transporter 1 | src substrate cortactin1110020L01Rikamplaxinems1 sequence (mammary tumor and squamous cell carcinoma-associated (p80/85 src substrate)oncogene EMS1 | |
| Modification date | 20180523 | 20180522 | |
| UniProtAcc | P21673 | Q14247 | |
| Ensembl transtripts involved in fusion gene | ENST00000379251, ENST00000379253, ENST00000379254, ENST00000379270, ENST00000489394, | ENST00000346329, ENST00000301843, ENST00000527622, ENST00000376561, ENST00000538675, | |
| Fusion gene scores | * DoF score | 6 X 10 X 2=120 | 8 X 7 X 8=448 |
| # samples | 11 | 16 | |
| ** MAII score | log2(11/120*10)=-0.125530882083859 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(16/448*10)=-1.48542682717024 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SAT1 [Title/Abstract] AND CTTN [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | PRAD | TCGA-EJ-7784-01A | SAT1 | chrX | 23804230 | + | CTTN | chr11 | 70281572 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3UTR | ENST00000379251 | ENST00000346329 | SAT1 | chrX | 23804230 | + | CTTN | chr11 | 70281572 | + |
| intron-3UTR | ENST00000379251 | ENST00000301843 | SAT1 | chrX | 23804230 | + | CTTN | chr11 | 70281572 | + |
| intron-intron | ENST00000379251 | ENST00000527622 | SAT1 | chrX | 23804230 | + | CTTN | chr11 | 70281572 | + |
| intron-intron | ENST00000379251 | ENST00000376561 | SAT1 | chrX | 23804230 | + | CTTN | chr11 | 70281572 | + |
| intron-intron | ENST00000379251 | ENST00000538675 | SAT1 | chrX | 23804230 | + | CTTN | chr11 | 70281572 | + |
| intron-3UTR | ENST00000379253 | ENST00000346329 | SAT1 | chrX | 23804230 | + | CTTN | chr11 | 70281572 | + |
| intron-3UTR | ENST00000379253 | ENST00000301843 | SAT1 | chrX | 23804230 | + | CTTN | chr11 | 70281572 | + |
| intron-intron | ENST00000379253 | ENST00000527622 | SAT1 | chrX | 23804230 | + | CTTN | chr11 | 70281572 | + |
| intron-intron | ENST00000379253 | ENST00000376561 | SAT1 | chrX | 23804230 | + | CTTN | chr11 | 70281572 | + |
| intron-intron | ENST00000379253 | ENST00000538675 | SAT1 | chrX | 23804230 | + | CTTN | chr11 | 70281572 | + |
| 5CDS-3UTR | ENST00000379254 | ENST00000346329 | SAT1 | chrX | 23804230 | + | CTTN | chr11 | 70281572 | + |
| 5CDS-3UTR | ENST00000379254 | ENST00000301843 | SAT1 | chrX | 23804230 | + | CTTN | chr11 | 70281572 | + |
| 5CDS-intron | ENST00000379254 | ENST00000527622 | SAT1 | chrX | 23804230 | + | CTTN | chr11 | 70281572 | + |
| 5CDS-intron | ENST00000379254 | ENST00000376561 | SAT1 | chrX | 23804230 | + | CTTN | chr11 | 70281572 | + |
| 5CDS-intron | ENST00000379254 | ENST00000538675 | SAT1 | chrX | 23804230 | + | CTTN | chr11 | 70281572 | + |
| 3UTR-3UTR | ENST00000379270 | ENST00000346329 | SAT1 | chrX | 23804230 | + | CTTN | chr11 | 70281572 | + |
| 3UTR-3UTR | ENST00000379270 | ENST00000301843 | SAT1 | chrX | 23804230 | + | CTTN | chr11 | 70281572 | + |
| 3UTR-intron | ENST00000379270 | ENST00000527622 | SAT1 | chrX | 23804230 | + | CTTN | chr11 | 70281572 | + |
| 3UTR-intron | ENST00000379270 | ENST00000376561 | SAT1 | chrX | 23804230 | + | CTTN | chr11 | 70281572 | + |
| 3UTR-intron | ENST00000379270 | ENST00000538675 | SAT1 | chrX | 23804230 | + | CTTN | chr11 | 70281572 | + |
| 3UTR-3UTR | ENST00000489394 | ENST00000346329 | SAT1 | chrX | 23804230 | + | CTTN | chr11 | 70281572 | + |
| 3UTR-3UTR | ENST00000489394 | ENST00000301843 | SAT1 | chrX | 23804230 | + | CTTN | chr11 | 70281572 | + |
| 3UTR-intron | ENST00000489394 | ENST00000527622 | SAT1 | chrX | 23804230 | + | CTTN | chr11 | 70281572 | + |
| 3UTR-intron | ENST00000489394 | ENST00000376561 | SAT1 | chrX | 23804230 | + | CTTN | chr11 | 70281572 | + |
| 3UTR-intron | ENST00000489394 | ENST00000538675 | SAT1 | chrX | 23804230 | + | CTTN | chr11 | 70281572 | + |
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FusionProtFeatures for SAT1_CTTN |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SAT1 | CTTN |