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Fusion gene ID: 32117 |
FusionGeneSummary for RPS4Y1_ARGLU1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: RPS4Y1_ARGLU1 | Fusion gene ID: 32117 | Hgene | Tgene | Gene symbol | RPS4Y1 | ARGLU1 | Gene ID | 6192 | 55082 |
| Gene name | ribosomal protein S4 Y-linked 1 | arginine and glutamate rich 1 | |
| Synonyms | RPS4Y|S4 | - | |
| Cytomap | Yp11.2 | 13q33.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | 40S ribosomal protein S4, Y isoform 140S ribosomal protein S4, Yribosomal protein S4, Y-linkedribosomal protein S4Ysmall ribosomal subunit protein eS4 | arginine and glutamate-rich protein 1 | |
| Modification date | 20180523 | 20180522 | |
| UniProtAcc | P22090 | Q9NWB6 | |
| Ensembl transtripts involved in fusion gene | ENST00000250784, ENST00000477725, | ENST00000400198, ENST00000472226, ENST00000375926, | |
| Fusion gene scores | * DoF score | 4 X 4 X 2=32 | 3 X 3 X 1=9 |
| # samples | 4 | 3 | |
| ** MAII score | log2(4/32*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(3/9*10)=1.73696559416621 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: RPS4Y1 [Title/Abstract] AND ARGLU1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BI047537 | RPS4Y1 | chrY | 2733176 | + | ARGLU1 | chr13 | 107220075 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000250784 | ENST00000400198 | RPS4Y1 | chrY | 2733176 | + | ARGLU1 | chr13 | 107220075 | + |
| 5CDS-intron | ENST00000250784 | ENST00000472226 | RPS4Y1 | chrY | 2733176 | + | ARGLU1 | chr13 | 107220075 | + |
| 5CDS-intron | ENST00000250784 | ENST00000375926 | RPS4Y1 | chrY | 2733176 | + | ARGLU1 | chr13 | 107220075 | + |
| 3UTR-3CDS | ENST00000477725 | ENST00000400198 | RPS4Y1 | chrY | 2733176 | + | ARGLU1 | chr13 | 107220075 | + |
| 3UTR-intron | ENST00000477725 | ENST00000472226 | RPS4Y1 | chrY | 2733176 | + | ARGLU1 | chr13 | 107220075 | + |
| 3UTR-intron | ENST00000477725 | ENST00000375926 | RPS4Y1 | chrY | 2733176 | + | ARGLU1 | chr13 | 107220075 | + |
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FusionProtFeatures for RPS4Y1_ARGLU1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| RPS4Y1 | ARGLU1 |