|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 31958 |
FusionGeneSummary for RPL7L1_MXRA7 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: RPL7L1_MXRA7 | Fusion gene ID: 31958 | Hgene | Tgene | Gene symbol | RPL7L1 | MXRA7 | Gene ID | 285855 | 439921 |
| Gene name | ribosomal protein L7 like 1 | matrix remodeling associated 7 | |
| Synonyms | dJ475N16.4 | - | |
| Cytomap | 6p21.1 | 17q25.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | 60S ribosomal protein L7-like 1large ribosomal subunit protein uL30-like 1 | matrix-remodeling-associated protein 7matrix-remodelling associated 7 | |
| Modification date | 20180523 | 20180529 | |
| UniProtAcc | Q6DKI1 | P84157 | |
| Ensembl transtripts involved in fusion gene | ENST00000493763, ENST00000397415, ENST00000304734, ENST00000424341, ENST00000602561, | ENST00000355797, ENST00000375036, ENST00000449428, ENST00000592148, ENST00000585519, ENST00000588114, ENST00000589082, | |
| Fusion gene scores | * DoF score | 5 X 4 X 4=80 | 5 X 4 X 4=80 |
| # samples | 5 | 7 | |
| ** MAII score | log2(5/80*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(7/80*10)=-0.192645077942396 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: RPL7L1 [Title/Abstract] AND MXRA7 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | CN277738 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-3UTR | ENST00000493763 | ENST00000355797 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| 3UTR-intron | ENST00000493763 | ENST00000375036 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| 3UTR-intron | ENST00000493763 | ENST00000449428 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| 3UTR-intron | ENST00000493763 | ENST00000592148 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| 3UTR-intron | ENST00000493763 | ENST00000585519 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| 3UTR-intron | ENST00000493763 | ENST00000588114 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| 3UTR-intron | ENST00000493763 | ENST00000589082 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| 3UTR-3UTR | ENST00000397415 | ENST00000355797 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| 3UTR-intron | ENST00000397415 | ENST00000375036 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| 3UTR-intron | ENST00000397415 | ENST00000449428 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| 3UTR-intron | ENST00000397415 | ENST00000592148 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| 3UTR-intron | ENST00000397415 | ENST00000585519 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| 3UTR-intron | ENST00000397415 | ENST00000588114 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| 3UTR-intron | ENST00000397415 | ENST00000589082 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| intron-3UTR | ENST00000304734 | ENST00000355797 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| intron-intron | ENST00000304734 | ENST00000375036 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| intron-intron | ENST00000304734 | ENST00000449428 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| intron-intron | ENST00000304734 | ENST00000592148 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| intron-intron | ENST00000304734 | ENST00000585519 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| intron-intron | ENST00000304734 | ENST00000588114 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| intron-intron | ENST00000304734 | ENST00000589082 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| 3UTR-3UTR | ENST00000424341 | ENST00000355797 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| 3UTR-intron | ENST00000424341 | ENST00000375036 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| 3UTR-intron | ENST00000424341 | ENST00000449428 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| 3UTR-intron | ENST00000424341 | ENST00000592148 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| 3UTR-intron | ENST00000424341 | ENST00000585519 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| 3UTR-intron | ENST00000424341 | ENST00000588114 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| 3UTR-intron | ENST00000424341 | ENST00000589082 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| intron-3UTR | ENST00000602561 | ENST00000355797 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| intron-intron | ENST00000602561 | ENST00000375036 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| intron-intron | ENST00000602561 | ENST00000449428 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| intron-intron | ENST00000602561 | ENST00000592148 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| intron-intron | ENST00000602561 | ENST00000585519 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| intron-intron | ENST00000602561 | ENST00000588114 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
| intron-intron | ENST00000602561 | ENST00000589082 | RPL7L1 | chr6 | 42854452 | + | MXRA7 | chr17 | 74672581 | - |
Top |
FusionProtFeatures for RPL7L1_MXRA7 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| RPL7L1 | MXRA7 |