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Fusion gene ID: 31935 |
FusionGeneSummary for RPL38_UBE2J2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: RPL38_UBE2J2 | Fusion gene ID: 31935 | Hgene | Tgene | Gene symbol | RPL38 | UBE2J2 | Gene ID | 6169 | 118424 |
| Gene name | ribosomal protein L38 | ubiquitin conjugating enzyme E2 J2 | |
| Synonyms | L38 | NCUBE-2|NCUBE2|PRO2121 | |
| Cytomap | 17q25.1 | 1p36.33 | |
| Type of gene | protein-coding | protein-coding | |
| Description | 60S ribosomal protein L38large ribosomal subunit protein eL38 | ubiquitin-conjugating enzyme E2 J2E2 ubiquitin-conjugating enzyme J2non-canonical ubiquitin-conjugating enzyme 2ubiquitin conjugating enzyme 6ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast)yeast UBC6 homolog | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | P63173 | Q8N2K1 | |
| Ensembl transtripts involved in fusion gene | ENST00000439590, ENST00000311111, ENST00000584577, ENST00000534490, ENST00000533498, | ENST00000347370, ENST00000349431, ENST00000339385, ENST00000348298, ENST00000400929, ENST00000360466, ENST00000400930, ENST00000491779, | |
| Fusion gene scores | * DoF score | 17 X 15 X 4=1020 | 6 X 5 X 2=60 |
| # samples | 19 | 6 | |
| ** MAII score | log2(19/1020*10)=-2.42449782852791 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(6/60*10)=0 | |
| Context | PubMed: RPL38 [Title/Abstract] AND UBE2J2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | RPL38 | GO:0002181 | cytoplasmic translation | 25957688 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | DB371044 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3UTR | ENST00000439590 | ENST00000347370 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-3UTR | ENST00000439590 | ENST00000349431 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-intron | ENST00000439590 | ENST00000339385 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-intron | ENST00000439590 | ENST00000348298 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-intron | ENST00000439590 | ENST00000400929 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-intron | ENST00000439590 | ENST00000360466 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-intron | ENST00000439590 | ENST00000400930 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-intron | ENST00000439590 | ENST00000491779 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-3UTR | ENST00000311111 | ENST00000347370 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-3UTR | ENST00000311111 | ENST00000349431 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-intron | ENST00000311111 | ENST00000339385 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-intron | ENST00000311111 | ENST00000348298 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-intron | ENST00000311111 | ENST00000400929 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-intron | ENST00000311111 | ENST00000360466 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-intron | ENST00000311111 | ENST00000400930 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-intron | ENST00000311111 | ENST00000491779 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-3UTR | ENST00000584577 | ENST00000347370 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-3UTR | ENST00000584577 | ENST00000349431 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-intron | ENST00000584577 | ENST00000339385 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-intron | ENST00000584577 | ENST00000348298 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-intron | ENST00000584577 | ENST00000400929 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-intron | ENST00000584577 | ENST00000360466 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-intron | ENST00000584577 | ENST00000400930 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-intron | ENST00000584577 | ENST00000491779 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-3UTR | ENST00000534490 | ENST00000347370 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-3UTR | ENST00000534490 | ENST00000349431 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-intron | ENST00000534490 | ENST00000339385 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-intron | ENST00000534490 | ENST00000348298 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-intron | ENST00000534490 | ENST00000400929 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-intron | ENST00000534490 | ENST00000360466 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-intron | ENST00000534490 | ENST00000400930 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-intron | ENST00000534490 | ENST00000491779 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-3UTR | ENST00000533498 | ENST00000347370 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-3UTR | ENST00000533498 | ENST00000349431 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-intron | ENST00000533498 | ENST00000339385 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-intron | ENST00000533498 | ENST00000348298 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-intron | ENST00000533498 | ENST00000400929 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-intron | ENST00000533498 | ENST00000360466 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-intron | ENST00000533498 | ENST00000400930 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
| intron-intron | ENST00000533498 | ENST00000491779 | RPL38 | chr17 | 72205942 | - | UBE2J2 | chr1 | 1189857 | + |
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FusionProtFeatures for RPL38_UBE2J2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| RPL38 | UBE2J2 |