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Fusion gene ID: 31745 |
FusionGeneSummary for RPAP1_IGKJ4 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: RPAP1_IGKJ4 | Fusion gene ID: 31745 | Hgene | Tgene | Gene symbol | RPAP1 | IGKJ4 | Gene ID | 26015 | 28947 |
| Gene name | RNA polymerase II associated protein 1 | immunoglobulin kappa joining 4 | |
| Synonyms | - | J4 | |
| Cytomap | 15q15.1 | 2p11.2 | |
| Type of gene | protein-coding | other | |
| Description | RNA polymerase II-associated protein 1 | - | |
| Modification date | 20180523 | 20180329 | |
| UniProtAcc | Q9BWH6 | ||
| Ensembl transtripts involved in fusion gene | ENST00000561603, ENST00000304330, ENST00000568413, | ENST00000390239, | |
| Fusion gene scores | * DoF score | 4 X 4 X 3=48 | 7 X 4 X 7=196 |
| # samples | 4 | 7 | |
| ** MAII score | log2(4/48*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(7/196*10)=-1.48542682717024 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: RPAP1 [Title/Abstract] AND IGKJ4 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | MESO | TCGA-3U-A98H-01A | RPAP1 | chr15 | 41815105 | - | IGKJ4 | chr2 | 89160432 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000561603 | ENST00000390239 | RPAP1 | chr15 | 41815105 | - | IGKJ4 | chr2 | 89160432 | - |
| intron-3CDS | ENST00000304330 | ENST00000390239 | RPAP1 | chr15 | 41815105 | - | IGKJ4 | chr2 | 89160432 | - |
| intron-3CDS | ENST00000568413 | ENST00000390239 | RPAP1 | chr15 | 41815105 | - | IGKJ4 | chr2 | 89160432 | - |
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FusionProtFeatures for RPAP1_IGKJ4 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| RPAP1 | IGKJ4 |