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Fusion gene ID: 31652 |
FusionGeneSummary for RNU6-1_SNORD91B |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: RNU6-1_SNORD91B | Fusion gene ID: 31652 | Hgene | Tgene | Gene symbol | RNU6-1 | SNORD91B | Gene ID | 26827 | 692208 |
| Gene name | RNA, U6 small nuclear 1 | small nucleolar RNA, C/D box 91B | |
| Synonyms | RNU6|RNU6A|U6|U6-1 | HBII-296b | |
| Cytomap | 15q23 | 17p13.3 | |
| Type of gene | snRNA | snoRNA | |
| Description | RNA, U6A small nuclear | - | |
| Modification date | 20180519 | 20180329 | |
| UniProtAcc | |||
| Ensembl transtripts involved in fusion gene | ENST00000383898, | ENST00000391250, | |
| Fusion gene scores | * DoF score | 2 X 2 X 2=8 | 1 X 1 X 1=1 |
| # samples | 2 | 1 | |
| ** MAII score | log2(2/8*10)=1.32192809488736 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: RNU6-1 [Title/Abstract] AND SNORD91B [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-A7-A0DC-01A | RNU6-1 | chr15 | 68132277 | - | SNORD91B | chr17 | 2232459 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-5UTR | ENST00000383898 | ENST00000391250 | RNU6-1 | chr15 | 68132277 | - | SNORD91B | chr17 | 2232459 | - |
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FusionProtFeatures for RNU6-1_SNORD91B |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| RNU6-1 | SNORD91B |