|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 31323 |
FusionGeneSummary for RMI2_MIPEP |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: RMI2_MIPEP | Fusion gene ID: 31323 | Hgene | Tgene | Gene symbol | RMI2 | MIPEP | Gene ID | 116028 | 4285 |
| Gene name | RecQ mediated genome instability 2 | mitochondrial intermediate peptidase | |
| Synonyms | BLAP18|C16orf75 | COXPD31|HMIP|MIP | |
| Cytomap | 16p13.13 | 13q12.12 | |
| Type of gene | protein-coding | protein-coding | |
| Description | recQ-mediated genome instability protein 2BLM-associated protein of 18 kDaRMI2, RecQ mediated genome instability 2, homolog | mitochondrial intermediate peptidase | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q96E14 | Q99797 | |
| Ensembl transtripts involved in fusion gene | ENST00000572173, ENST00000572992, ENST00000381820, ENST00000312499, ENST00000576027, | ENST00000382172, ENST00000469167, | |
| Fusion gene scores | * DoF score | 8 X 8 X 2=128 | 9 X 7 X 7=441 |
| # samples | 8 | 9 | |
| ** MAII score | log2(8/128*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(9/441*10)=-2.29278174922785 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: RMI2 [Title/Abstract] AND MIPEP [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | DB341880 | RMI2 | chr16 | 11370061 | + | MIPEP | chr13 | 24375503 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-intron | ENST00000572173 | ENST00000382172 | RMI2 | chr16 | 11370061 | + | MIPEP | chr13 | 24375503 | + |
| intron-intron | ENST00000572173 | ENST00000469167 | RMI2 | chr16 | 11370061 | + | MIPEP | chr13 | 24375503 | + |
| intron-intron | ENST00000572992 | ENST00000382172 | RMI2 | chr16 | 11370061 | + | MIPEP | chr13 | 24375503 | + |
| intron-intron | ENST00000572992 | ENST00000469167 | RMI2 | chr16 | 11370061 | + | MIPEP | chr13 | 24375503 | + |
| intron-intron | ENST00000381820 | ENST00000382172 | RMI2 | chr16 | 11370061 | + | MIPEP | chr13 | 24375503 | + |
| intron-intron | ENST00000381820 | ENST00000469167 | RMI2 | chr16 | 11370061 | + | MIPEP | chr13 | 24375503 | + |
| intron-intron | ENST00000312499 | ENST00000382172 | RMI2 | chr16 | 11370061 | + | MIPEP | chr13 | 24375503 | + |
| intron-intron | ENST00000312499 | ENST00000469167 | RMI2 | chr16 | 11370061 | + | MIPEP | chr13 | 24375503 | + |
| intron-intron | ENST00000576027 | ENST00000382172 | RMI2 | chr16 | 11370061 | + | MIPEP | chr13 | 24375503 | + |
| intron-intron | ENST00000576027 | ENST00000469167 | RMI2 | chr16 | 11370061 | + | MIPEP | chr13 | 24375503 | + |
Top |
FusionProtFeatures for RMI2_MIPEP |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| RMI2 | MIPEP |