	FusionGeneSummary
	FusionProtFeature
	FusionGeneSequence
	FusionGenePPI
	RelatedDrugs
	RelatedDiseases

Fusion gene ID: 31243

FusionGeneSummary for RIF1_RIF1

Fusion gene summary

Fusion gene information	Fusion gene name: RIF1_RIF1
	Fusion gene ID: 31243
		Hgene	Tgene
	Gene symbol	RIF1	RIF1
	Gene ID	55791	55791
	Gene name	ligand dependent nuclear receptor interacting factor 1	ligand dependent nuclear receptor interacting factor 1
	Synonyms	C1orf103\|RIF1	C1orf103\|RIF1
	Cytomap	1p13.3	1p13.3
	Type of gene	protein-coding	protein-coding
	Description	ligand-dependent nuclear receptor-interacting factor 1receptor-interacting factor 1	ligand-dependent nuclear receptor-interacting factor 1receptor-interacting factor 1
	Modification date	20180523	20180523
	UniProtAcc	Q5UIP0	Q5UIP0
	Ensembl transtripts involved in fusion gene	ENST00000444746, ENST00000453091, ENST00000428287, ENST00000243326, ENST00000430328, ENST00000433166, ENST00000457745,	ENST00000444746, ENST00000453091, ENST00000428287, ENST00000243326, ENST00000430328, ENST00000433166, ENST00000457745,
Fusion gene scores	* DoF score	4 X 4 X 3=48	3 X 3 X 2=18
	# samples	5	4
	** MAII score	log2(5/48*10)=0.0588936890535686 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0	log2(4/18*10)=1.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0
Context	PubMed: RIF1 [Title/Abstract] AND RIF1 [Title/Abstract] AND fusion [Title/Abstract]
Functional or gene categories assigned by FusionGDB annotation

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Data type	Source	Cancer type	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChiTaRS3.1			AW937387	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
ChiTaRS3.1			AW937408	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-

* LD: Li Ding group's fusion gene list
RV: Roel Verhaak group's fusion gene list
ChiTaRs fusion database

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
intron-intron	ENST00000444746	ENST00000444746	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000444746	ENST00000453091	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000444746	ENST00000428287	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000444746	ENST00000243326	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000444746	ENST00000430328	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000444746	ENST00000433166	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000444746	ENST00000457745	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000453091	ENST00000444746	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000453091	ENST00000453091	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000453091	ENST00000428287	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000453091	ENST00000243326	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000453091	ENST00000430328	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000453091	ENST00000433166	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000453091	ENST00000457745	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000428287	ENST00000444746	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000428287	ENST00000453091	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000428287	ENST00000428287	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000428287	ENST00000243326	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000428287	ENST00000430328	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000428287	ENST00000433166	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000428287	ENST00000457745	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000243326	ENST00000444746	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000243326	ENST00000453091	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000243326	ENST00000428287	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000243326	ENST00000243326	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000243326	ENST00000430328	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000243326	ENST00000433166	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000243326	ENST00000457745	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000430328	ENST00000444746	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000430328	ENST00000453091	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000430328	ENST00000428287	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000430328	ENST00000243326	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000430328	ENST00000430328	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000430328	ENST00000433166	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000430328	ENST00000457745	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000433166	ENST00000444746	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000433166	ENST00000453091	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000433166	ENST00000428287	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000433166	ENST00000243326	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000433166	ENST00000430328	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000433166	ENST00000433166	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000433166	ENST00000457745	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000457745	ENST00000444746	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000457745	ENST00000453091	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000457745	ENST00000428287	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000457745	ENST00000243326	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000457745	ENST00000430328	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000457745	ENST00000433166	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-
intron-intron	ENST00000457745	ENST00000457745	RIF1	chr2	152357908	+	RIF1	chr2	152352781	-

Top

FusionProtFeatures for RIF1_RIF1

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
RIF1 Q5UIP0	RIF1 Q5UIP0

Home

Download

Statistics

Examples

Help

Contact

Fusion gene ID: 31243

FusionGeneSummary for RIF1_RIF1

FusionProtFeatures for RIF1_RIF1