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Fusion gene ID: 3101 |
FusionGeneSummary for ATAD5_MN1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ATAD5_MN1 | Fusion gene ID: 3101 | Hgene | Tgene | Gene symbol | ATAD5 | MN1 | Gene ID | 79915 | 4330 |
| Gene name | ATPase family, AAA domain containing 5 | MN1 proto-oncogene, transcriptional regulator | |
| Synonyms | C17orf41|ELG1|FRAG1 | MGCR|MGCR1|MGCR1-PEN|dJ353E16.2 | |
| Cytomap | 17q11.2 | 22q12.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ATPase family AAA domain-containing protein 5chromosome fragility associated gene 1chromosome fragility-associated gene 1 proteinenhanced level of genomic instability 1 homolog | transcriptional activator MN1meningioma (disrupted in balanced translocation) 1meningioma (translocation balanced)meningioma chromosome region 1probable tumor suppressor protein MN1 | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q96QE3 | Q10571 | |
| Ensembl transtripts involved in fusion gene | ENST00000321990, | ENST00000302326, ENST00000497225, | |
| Fusion gene scores | * DoF score | 7 X 7 X 6=294 | 1 X 1 X 1=1 |
| # samples | 7 | 1 | |
| ** MAII score | log2(7/294*10)=-2.0703893278914 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: ATAD5 [Title/Abstract] AND MN1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | AI024583 | ATAD5 | chr17 | 29160560 | + | MN1 | chr22 | 28156876 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-intron | ENST00000321990 | ENST00000302326 | ATAD5 | chr17 | 29160560 | + | MN1 | chr22 | 28156876 | + |
| intron-intron | ENST00000321990 | ENST00000497225 | ATAD5 | chr17 | 29160560 | + | MN1 | chr22 | 28156876 | + |
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FusionProtFeatures for ATAD5_MN1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ATAD5 | MN1 |