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Fusion gene ID: 30998 |
FusionGeneSummary for REV1_REV1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: REV1_REV1 | Fusion gene ID: 30998 | Hgene | Tgene | Gene symbol | REV1 | REV1 | Gene ID | 51455 | 51455 |
| Gene name | REV1, DNA directed polymerase | REV1, DNA directed polymerase | |
| Synonyms | AIBP80|REV1L | AIBP80|REV1L | |
| Cytomap | 2q11.2 | 2q11.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | DNA repair protein REV1REV1 homologREV1, polymerase (DNA directed)REV1- likealpha integrin-binding protein 80rev1-like terminal deoxycytidyl transferase | DNA repair protein REV1REV1 homologREV1, polymerase (DNA directed)REV1- likealpha integrin-binding protein 80rev1-like terminal deoxycytidyl transferase | |
| Modification date | 20180522 | 20180522 | |
| UniProtAcc | Q9UBZ9 | Q9UBZ9 | |
| Ensembl transtripts involved in fusion gene | ENST00000393445, ENST00000258428, ENST00000465835, | ENST00000393445, ENST00000258428, ENST00000465835, | |
| Fusion gene scores | * DoF score | 8 X 7 X 4=224 | 2 X 2 X 2=8 |
| # samples | 7 | 2 | |
| ** MAII score | log2(7/224*10)=-1.67807190511264 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: REV1 [Title/Abstract] AND REV1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | REV1 | GO:0009411 | response to UV | 11485998 |
| Tgene | REV1 | GO:0009411 | response to UV | 11485998 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BU675470 | REV1 | chr2 | 100022849 | - | REV1 | chr2 | 100022393 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000393445 | ENST00000393445 | REV1 | chr2 | 100022849 | - | REV1 | chr2 | 100022393 | + |
| intron-3CDS | ENST00000393445 | ENST00000258428 | REV1 | chr2 | 100022849 | - | REV1 | chr2 | 100022393 | + |
| intron-5UTR | ENST00000393445 | ENST00000465835 | REV1 | chr2 | 100022849 | - | REV1 | chr2 | 100022393 | + |
| intron-3CDS | ENST00000258428 | ENST00000393445 | REV1 | chr2 | 100022849 | - | REV1 | chr2 | 100022393 | + |
| intron-3CDS | ENST00000258428 | ENST00000258428 | REV1 | chr2 | 100022849 | - | REV1 | chr2 | 100022393 | + |
| intron-5UTR | ENST00000258428 | ENST00000465835 | REV1 | chr2 | 100022849 | - | REV1 | chr2 | 100022393 | + |
| intron-3CDS | ENST00000465835 | ENST00000393445 | REV1 | chr2 | 100022849 | - | REV1 | chr2 | 100022393 | + |
| intron-3CDS | ENST00000465835 | ENST00000258428 | REV1 | chr2 | 100022849 | - | REV1 | chr2 | 100022393 | + |
| intron-5UTR | ENST00000465835 | ENST00000465835 | REV1 | chr2 | 100022849 | - | REV1 | chr2 | 100022393 | + |
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FusionProtFeatures for REV1_REV1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| REV1 | REV1 |