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Fusion gene ID: 30571 |
FusionGeneSummary for RASSF4_BPGM |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: RASSF4_BPGM | Fusion gene ID: 30571 | Hgene | Tgene | Gene symbol | RASSF4 | BPGM | Gene ID | 83937 | 669 |
| Gene name | Ras association domain family member 4 | bisphosphoglycerate mutase | |
| Synonyms | AD037 | DPGM | |
| Cytomap | 10q11.21 | 7q33 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ras association domain-containing protein 4Ras association (RalGDS/AF-6) domain family 4Ras association (RalGDS/AF-6) domain family member 4Ras association domain family 4tumor suppressor RASSF4 | bisphosphoglycerate mutase2,3-bisphosphoglycerate mutase, erythrocyte2,3-bisphosphoglycerate synthase2,3-diphosphoglycerate mutaseBPG-dependent PGAMerythrocyte 2,3-bisphosphoglycerate mutasetestis secretory sperm-binding protein Li 202a | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | Q9H2L5 | P07738 | |
| Ensembl transtripts involved in fusion gene | ENST00000334940, ENST00000374417, ENST00000340258, ENST00000472561, | ENST00000344924, ENST00000418040, ENST00000393132, | |
| Fusion gene scores | * DoF score | 5 X 5 X 1=25 | 2 X 2 X 1=4 |
| # samples | 5 | 2 | |
| ** MAII score | log2(5/25*10)=1 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(2/4*10)=2.32192809488736 | |
| Context | PubMed: RASSF4 [Title/Abstract] AND BPGM [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | AI380175 | RASSF4 | chr10 | 45471902 | + | BPGM | chr7 | 134364356 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3UTR | ENST00000334940 | ENST00000344924 | RASSF4 | chr10 | 45471902 | + | BPGM | chr7 | 134364356 | - |
| intron-3UTR | ENST00000334940 | ENST00000418040 | RASSF4 | chr10 | 45471902 | + | BPGM | chr7 | 134364356 | - |
| intron-3UTR | ENST00000334940 | ENST00000393132 | RASSF4 | chr10 | 45471902 | + | BPGM | chr7 | 134364356 | - |
| intron-3UTR | ENST00000374417 | ENST00000344924 | RASSF4 | chr10 | 45471902 | + | BPGM | chr7 | 134364356 | - |
| intron-3UTR | ENST00000374417 | ENST00000418040 | RASSF4 | chr10 | 45471902 | + | BPGM | chr7 | 134364356 | - |
| intron-3UTR | ENST00000374417 | ENST00000393132 | RASSF4 | chr10 | 45471902 | + | BPGM | chr7 | 134364356 | - |
| intron-3UTR | ENST00000340258 | ENST00000344924 | RASSF4 | chr10 | 45471902 | + | BPGM | chr7 | 134364356 | - |
| intron-3UTR | ENST00000340258 | ENST00000418040 | RASSF4 | chr10 | 45471902 | + | BPGM | chr7 | 134364356 | - |
| intron-3UTR | ENST00000340258 | ENST00000393132 | RASSF4 | chr10 | 45471902 | + | BPGM | chr7 | 134364356 | - |
| intron-3UTR | ENST00000472561 | ENST00000344924 | RASSF4 | chr10 | 45471902 | + | BPGM | chr7 | 134364356 | - |
| intron-3UTR | ENST00000472561 | ENST00000418040 | RASSF4 | chr10 | 45471902 | + | BPGM | chr7 | 134364356 | - |
| intron-3UTR | ENST00000472561 | ENST00000393132 | RASSF4 | chr10 | 45471902 | + | BPGM | chr7 | 134364356 | - |
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FusionProtFeatures for RASSF4_BPGM |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| RASSF4 | BPGM |