	FusionGeneSummary
	FusionProtFeature
	FusionGeneSequence
	FusionGenePPI
	RelatedDrugs
	RelatedDiseases

Fusion gene ID: 30236

FusionGeneSummary for RAI14_SLC26A7

Fusion gene summary

Fusion gene information	Fusion gene name: RAI14_SLC26A7
	Fusion gene ID: 30236
		Hgene	Tgene
	Gene symbol	RAI14	SLC26A7
	Gene ID	26064	115111
	Gene name	retinoic acid induced 14	solute carrier family 26 member 7
	Synonyms	NORPEG\|RAI13	SUT2
	Cytomap	5p13.2	8q21.3
	Type of gene	protein-coding	protein-coding
	Description	ankycorbinankyrin repeat and coiled-coil structure-containing proteinnovel retinal pigment epithelial cell proteinretinoic acid-induced protein 14	anion exchange transportersolute carrier family 26 (anion exchanger), member 7sulfate anion transporter
	Modification date	20180522	20180523
	UniProtAcc	Q9P0K7	Q8TE54
	Ensembl transtripts involved in fusion gene	ENST00000265109, ENST00000512629, ENST00000428746, ENST00000503673, ENST00000515799, ENST00000506376, ENST00000507276, ENST00000397449,	ENST00000523719, ENST00000276609, ENST00000309536, ENST00000520249,
Fusion gene scores	* DoF score	11 X 8 X 4=352	7 X 6 X 6=252
	# samples	13	7
	** MAII score	log2(13/352*10)=-1.43706380560884 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(7/252*10)=-1.84799690655495 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: RAI14 [Title/Abstract] AND SLC26A7 [Title/Abstract] AND fusion [Title/Abstract]
Functional or gene categories assigned by FusionGDB annotation

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	SLC26A7	GO:0006820	anion transport	11834742
Tgene	SLC26A7	GO:0006821	chloride transport	1183472
Tgene	SLC26A7	GO:0008272	sulfate transport	1183472
Tgene	SLC26A7	GO:0019532	oxalate transport	1183472

Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Data type	Source	Cancer type	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChiTaRS3.1			BF987124	RAI14	chr5	34824268	-	SLC26A7	chr8	92295186	+

* LD: Li Ding group's fusion gene list
RV: Roel Verhaak group's fusion gene list
ChiTaRs fusion database

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000265109	ENST00000523719	RAI14	chr5	34824268	-	SLC26A7	chr8	92295186	+
5CDS-intron	ENST00000265109	ENST00000276609	RAI14	chr5	34824268	-	SLC26A7	chr8	92295186	+
5CDS-intron	ENST00000265109	ENST00000309536	RAI14	chr5	34824268	-	SLC26A7	chr8	92295186	+
5CDS-intron	ENST00000265109	ENST00000520249	RAI14	chr5	34824268	-	SLC26A7	chr8	92295186	+
5CDS-intron	ENST00000512629	ENST00000523719	RAI14	chr5	34824268	-	SLC26A7	chr8	92295186	+
5CDS-intron	ENST00000512629	ENST00000276609	RAI14	chr5	34824268	-	SLC26A7	chr8	92295186	+
5CDS-intron	ENST00000512629	ENST00000309536	RAI14	chr5	34824268	-	SLC26A7	chr8	92295186	+
5CDS-intron	ENST00000512629	ENST00000520249	RAI14	chr5	34824268	-	SLC26A7	chr8	92295186	+
5CDS-intron	ENST00000428746	ENST00000523719	RAI14	chr5	34824268	-	SLC26A7	chr8	92295186	+
5CDS-intron	ENST00000428746	ENST00000276609	RAI14	chr5	34824268	-	SLC26A7	chr8	92295186	+
5CDS-intron	ENST00000428746	ENST00000309536	RAI14	chr5	34824268	-	SLC26A7	chr8	92295186	+
5CDS-intron	ENST00000428746	ENST00000520249	RAI14	chr5	34824268	-	SLC26A7	chr8	92295186	+
5CDS-intron	ENST00000503673	ENST00000523719	RAI14	chr5	34824268	-	SLC26A7	chr8	92295186	+
5CDS-intron	ENST00000503673	ENST00000276609	RAI14	chr5	34824268	-	SLC26A7	chr8	92295186	+
5CDS-intron	ENST00000503673	ENST00000309536	RAI14	chr5	34824268	-	SLC26A7	chr8	92295186	+
5CDS-intron	ENST00000503673	ENST00000520249	RAI14	chr5	34824268	-	SLC26A7	chr8	92295186	+
5CDS-intron	ENST00000515799	ENST00000523719	RAI14	chr5	34824268	-	SLC26A7	chr8	92295186	+
5CDS-intron	ENST00000515799	ENST00000276609	RAI14	chr5	34824268	-	SLC26A7	chr8	92295186	+
5CDS-intron	ENST00000515799	ENST00000309536	RAI14	chr5	34824268	-	SLC26A7	chr8	92295186	+
5CDS-intron	ENST00000515799	ENST00000520249	RAI14	chr5	34824268	-	SLC26A7	chr8	92295186	+
5CDS-intron	ENST00000506376	ENST00000523719	RAI14	chr5	34824268	-	SLC26A7	chr8	92295186	+
5CDS-intron	ENST00000506376	ENST00000276609	RAI14	chr5	34824268	-	SLC26A7	chr8	92295186	+
5CDS-intron	ENST00000506376	ENST00000309536	RAI14	chr5	34824268	-	SLC26A7	chr8	92295186	+
5CDS-intron	ENST00000506376	ENST00000520249	RAI14	chr5	34824268	-	SLC26A7	chr8	92295186	+
intron-intron	ENST00000507276	ENST00000523719	RAI14	chr5	34824268	-	SLC26A7	chr8	92295186	+
intron-intron	ENST00000507276	ENST00000276609	RAI14	chr5	34824268	-	SLC26A7	chr8	92295186	+
intron-intron	ENST00000507276	ENST00000309536	RAI14	chr5	34824268	-	SLC26A7	chr8	92295186	+
intron-intron	ENST00000507276	ENST00000520249	RAI14	chr5	34824268	-	SLC26A7	chr8	92295186	+
5CDS-intron	ENST00000397449	ENST00000523719	RAI14	chr5	34824268	-	SLC26A7	chr8	92295186	+
5CDS-intron	ENST00000397449	ENST00000276609	RAI14	chr5	34824268	-	SLC26A7	chr8	92295186	+
5CDS-intron	ENST00000397449	ENST00000309536	RAI14	chr5	34824268	-	SLC26A7	chr8	92295186	+
5CDS-intron	ENST00000397449	ENST00000520249	RAI14	chr5	34824268	-	SLC26A7	chr8	92295186	+

Top

FusionProtFeatures for RAI14_SLC26A7

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
RAI14 Q9P0K7	SLC26A7 Q8TE54

Home

Download

Statistics

Examples

Help

Contact

Fusion gene ID: 30236

FusionGeneSummary for RAI14_SLC26A7

FusionProtFeatures for RAI14_SLC26A7