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Fusion gene ID: 30212 |
FusionGeneSummary for RAE1_ADNP |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: RAE1_ADNP | Fusion gene ID: 30212 | Hgene | Tgene | Gene symbol | RAE1 | ADNP | Gene ID | 8480 | 23394 |
| Gene name | ribonucleic acid export 1 | activity dependent neuroprotector homeobox | |
| Synonyms | MIG14|MRNP41|Mnrp41|dJ481F12.3|dJ800J21.1 | ADNP1|HVDAS|MRD28 | |
| Cytomap | 20q13.31 | 20q13.13 | |
| Type of gene | protein-coding | protein-coding | |
| Description | mRNA export factorRAE1 RNA export 1 homologhomolog of yeast Rae1 (Bharathi) mRNA-associated protein of 41 kDa (Kraemer)mRNA export proteinmRNA-associated protein MRNP 41mRNA-binding protein, 41-kDmigration-inducing gene 14rae1 protein homolog | activity-dependent neuroprotector homeobox proteinADNP homeobox 1activity-dependent neuroprotective proteinactivity-dependent neuroprotector | |
| Modification date | 20180523 | 20180522 | |
| UniProtAcc | P78406 | Q9H2P0 | |
| Ensembl transtripts involved in fusion gene | ENST00000395841, ENST00000371242, ENST00000527947, ENST00000395840, | ENST00000396029, ENST00000396032, ENST00000371602, ENST00000349014, | |
| Fusion gene scores | * DoF score | 2 X 2 X 2=8 | 5 X 4 X 3=60 |
| # samples | 2 | 4 | |
| ** MAII score | log2(2/8*10)=1.32192809488736 | log2(4/60*10)=-0.584962500721156 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: RAE1 [Title/Abstract] AND ADNP [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | SKCM | TCGA-EB-A5VU-01A | RAE1 | chr20 | 55931594 | + | ADNP | chr20 | 49520538 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-5UTR | ENST00000395841 | ENST00000396029 | RAE1 | chr20 | 55931594 | + | ADNP | chr20 | 49520538 | - |
| 5CDS-5UTR | ENST00000395841 | ENST00000396032 | RAE1 | chr20 | 55931594 | + | ADNP | chr20 | 49520538 | - |
| 5CDS-5UTR | ENST00000395841 | ENST00000371602 | RAE1 | chr20 | 55931594 | + | ADNP | chr20 | 49520538 | - |
| 5CDS-5UTR | ENST00000395841 | ENST00000349014 | RAE1 | chr20 | 55931594 | + | ADNP | chr20 | 49520538 | - |
| 5CDS-5UTR | ENST00000371242 | ENST00000396029 | RAE1 | chr20 | 55931594 | + | ADNP | chr20 | 49520538 | - |
| 5CDS-5UTR | ENST00000371242 | ENST00000396032 | RAE1 | chr20 | 55931594 | + | ADNP | chr20 | 49520538 | - |
| 5CDS-5UTR | ENST00000371242 | ENST00000371602 | RAE1 | chr20 | 55931594 | + | ADNP | chr20 | 49520538 | - |
| 5CDS-5UTR | ENST00000371242 | ENST00000349014 | RAE1 | chr20 | 55931594 | + | ADNP | chr20 | 49520538 | - |
| 5CDS-5UTR | ENST00000527947 | ENST00000396029 | RAE1 | chr20 | 55931594 | + | ADNP | chr20 | 49520538 | - |
| 5CDS-5UTR | ENST00000527947 | ENST00000396032 | RAE1 | chr20 | 55931594 | + | ADNP | chr20 | 49520538 | - |
| 5CDS-5UTR | ENST00000527947 | ENST00000371602 | RAE1 | chr20 | 55931594 | + | ADNP | chr20 | 49520538 | - |
| 5CDS-5UTR | ENST00000527947 | ENST00000349014 | RAE1 | chr20 | 55931594 | + | ADNP | chr20 | 49520538 | - |
| 5CDS-5UTR | ENST00000395840 | ENST00000396029 | RAE1 | chr20 | 55931594 | + | ADNP | chr20 | 49520538 | - |
| 5CDS-5UTR | ENST00000395840 | ENST00000396032 | RAE1 | chr20 | 55931594 | + | ADNP | chr20 | 49520538 | - |
| 5CDS-5UTR | ENST00000395840 | ENST00000371602 | RAE1 | chr20 | 55931594 | + | ADNP | chr20 | 49520538 | - |
| 5CDS-5UTR | ENST00000395840 | ENST00000349014 | RAE1 | chr20 | 55931594 | + | ADNP | chr20 | 49520538 | - |
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FusionProtFeatures for RAE1_ADNP |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| RAE1 | ADNP |