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Fusion gene ID: 29692 |
FusionGeneSummary for PUS7_EFCAB10 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PUS7_EFCAB10 | Fusion gene ID: 29692 | Hgene | Tgene | Gene symbol | PUS7 | EFCAB10 | Gene ID | 54517 | 100130771 |
| Gene name | pseudouridylate synthase 7 | EF-hand calcium binding domain 10 | |
| Synonyms | - | - | |
| Cytomap | 7q22.3 | 7q22.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | pseudouridylate synthase 7 homologpseudouridylate synthase 7 (putative) | EF-hand calcium-binding domain-containing protein 10EF-hand domain-containing protein | |
| Modification date | 20180523 | 20180421 | |
| UniProtAcc | Q96PZ0 | A6NFE3 | |
| Ensembl transtripts involved in fusion gene | ENST00000356362, ENST00000469408, | ENST00000480514, ENST00000485614, ENST00000486180, ENST00000490493, ENST00000460135, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 3 X 1 X 3=9 |
| # samples | 1 | 3 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(3/9*10)=1.73696559416621 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: PUS7 [Title/Abstract] AND EFCAB10 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-E2-A1LE-01A | PUS7 | chr7 | 105162499 | - | EFCAB10 | chr7 | 105210018 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5UTR-3CDS | ENST00000356362 | ENST00000480514 | PUS7 | chr7 | 105162499 | - | EFCAB10 | chr7 | 105210018 | - |
| 5UTR-3CDS | ENST00000356362 | ENST00000485614 | PUS7 | chr7 | 105162499 | - | EFCAB10 | chr7 | 105210018 | - |
| 5UTR-3CDS | ENST00000356362 | ENST00000486180 | PUS7 | chr7 | 105162499 | - | EFCAB10 | chr7 | 105210018 | - |
| 5UTR-5UTR | ENST00000356362 | ENST00000490493 | PUS7 | chr7 | 105162499 | - | EFCAB10 | chr7 | 105210018 | - |
| 5UTR-intron | ENST00000356362 | ENST00000460135 | PUS7 | chr7 | 105162499 | - | EFCAB10 | chr7 | 105210018 | - |
| 5UTR-3CDS | ENST00000469408 | ENST00000480514 | PUS7 | chr7 | 105162499 | - | EFCAB10 | chr7 | 105210018 | - |
| 5UTR-3CDS | ENST00000469408 | ENST00000485614 | PUS7 | chr7 | 105162499 | - | EFCAB10 | chr7 | 105210018 | - |
| 5UTR-3CDS | ENST00000469408 | ENST00000486180 | PUS7 | chr7 | 105162499 | - | EFCAB10 | chr7 | 105210018 | - |
| 5UTR-5UTR | ENST00000469408 | ENST00000490493 | PUS7 | chr7 | 105162499 | - | EFCAB10 | chr7 | 105210018 | - |
| 5UTR-intron | ENST00000469408 | ENST00000460135 | PUS7 | chr7 | 105162499 | - | EFCAB10 | chr7 | 105210018 | - |
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FusionProtFeatures for PUS7_EFCAB10 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PUS7 | EFCAB10 |