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Fusion gene ID: 27823 |
FusionGeneSummary for PNISR_TAF1D |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PNISR_TAF1D | Fusion gene ID: 27823 | Hgene | Tgene | Gene symbol | PNISR | TAF1D | Gene ID | 25957 | 79101 |
| Gene name | PNN interacting serine and arginine rich protein | TATA-box binding protein associated factor, RNA polymerase I subunit D | |
| Synonyms | C6orf111|HSPC306|SFRS18|SRrp130|bA98I9.2 | JOSD3|RAFI41|TAF(I)41|TAFI41 | |
| Cytomap | 6q16.2 | 11q21 | |
| Type of gene | protein-coding | protein-coding | |
| Description | arginine/serine-rich protein PNISRPNN-interacting serine/arginine-rich proteinSR-related proteinSR-rich proteinserine-arginine-rich-splicing regulatory protein 130splicing factor, arginine/serine-rich 130splicing factor, arginine/serine-rich 18 | TATA box-binding protein-associated factor RNA polymerase I subunit DJosephin domain containing 3RNA polymerase I-specific TBP-associated factor 41 kDaTATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDaTATA box-binding protein | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q8TF01 | Q9H5J8 | |
| Ensembl transtripts involved in fusion gene | ENST00000369239, ENST00000438806, ENST00000466057, | ENST00000546088, ENST00000448108, | |
| Fusion gene scores | * DoF score | 3 X 4 X 2=24 | 6 X 6 X 4=144 |
| # samples | 5 | 7 | |
| ** MAII score | log2(5/24*10)=1.05889368905357 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(7/144*10)=-1.04064198449735 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: PNISR [Title/Abstract] AND TAF1D [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-JL-A3YW-01A | PNISR | chr6 | 99858617 | - | TAF1D | chr11 | 93465457 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-5UTR | ENST00000369239 | ENST00000546088 | PNISR | chr6 | 99858617 | - | TAF1D | chr11 | 93465457 | - |
| 5CDS-intron | ENST00000369239 | ENST00000448108 | PNISR | chr6 | 99858617 | - | TAF1D | chr11 | 93465457 | - |
| 5CDS-5UTR | ENST00000438806 | ENST00000546088 | PNISR | chr6 | 99858617 | - | TAF1D | chr11 | 93465457 | - |
| 5CDS-intron | ENST00000438806 | ENST00000448108 | PNISR | chr6 | 99858617 | - | TAF1D | chr11 | 93465457 | - |
| intron-5UTR | ENST00000466057 | ENST00000546088 | PNISR | chr6 | 99858617 | - | TAF1D | chr11 | 93465457 | - |
| intron-intron | ENST00000466057 | ENST00000448108 | PNISR | chr6 | 99858617 | - | TAF1D | chr11 | 93465457 | - |
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FusionProtFeatures for PNISR_TAF1D |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PNISR | TAF1D |