|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 276 |
FusionGeneSummary for ABLIM3_ALB |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ABLIM3_ALB | Fusion gene ID: 276 | Hgene | Tgene | Gene symbol | ABLIM3 | ALB | Gene ID | 22885 | 213 |
| Gene name | actin binding LIM protein family member 3 | albumin | |
| Synonyms | HMFN1661 | HSA|PRO0883|PRO0903|PRO1341 | |
| Cytomap | 5q32 | 4q13.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | actin-binding LIM protein 3abLIM-3 | serum albumin | |
| Modification date | 20180523 | 20180522 | |
| UniProtAcc | O94929 | P02768 | |
| Ensembl transtripts involved in fusion gene | ENST00000326685, ENST00000356541, ENST00000309868, ENST00000506113, ENST00000504238, ENST00000508983, ENST00000517451, ENST00000519549, | ENST00000295897, ENST00000415165, ENST00000503124, ENST00000509063, ENST00000401494, ENST00000505649, | |
| Fusion gene scores | * DoF score | 3 X 3 X 2=18 | 27 X 26 X 2=1404 |
| # samples | 3 | 33 | |
| ** MAII score | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(33/1404*10)=-2.08900500605874 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ABLIM3 [Title/Abstract] AND ALB [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | ALB | GO:0009267 | cellular response to starvation | 16245148 |
| Tgene | ALB | GO:0019836 | hemolysis by symbiont of host erythrocytes | 16394536 |
| Tgene | ALB | GO:0043066 | negative regulation of apoptotic process | 16153637 |
| Tgene | ALB | GO:0051659 | maintenance of mitochondrion location | 16153637 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | AV654807 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-5UTR | ENST00000326685 | ENST00000295897 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000326685 | ENST00000415165 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000326685 | ENST00000503124 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000326685 | ENST00000509063 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000326685 | ENST00000401494 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-intron | ENST00000326685 | ENST00000505649 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000356541 | ENST00000295897 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000356541 | ENST00000415165 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000356541 | ENST00000503124 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000356541 | ENST00000509063 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000356541 | ENST00000401494 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-intron | ENST00000356541 | ENST00000505649 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000309868 | ENST00000295897 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000309868 | ENST00000415165 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000309868 | ENST00000503124 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000309868 | ENST00000509063 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000309868 | ENST00000401494 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-intron | ENST00000309868 | ENST00000505649 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000506113 | ENST00000295897 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000506113 | ENST00000415165 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000506113 | ENST00000503124 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000506113 | ENST00000509063 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000506113 | ENST00000401494 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-intron | ENST00000506113 | ENST00000505649 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000504238 | ENST00000295897 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000504238 | ENST00000415165 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000504238 | ENST00000503124 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000504238 | ENST00000509063 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000504238 | ENST00000401494 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-intron | ENST00000504238 | ENST00000505649 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000508983 | ENST00000295897 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000508983 | ENST00000415165 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000508983 | ENST00000503124 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000508983 | ENST00000509063 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000508983 | ENST00000401494 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-intron | ENST00000508983 | ENST00000505649 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000517451 | ENST00000295897 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000517451 | ENST00000415165 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000517451 | ENST00000503124 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000517451 | ENST00000509063 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000517451 | ENST00000401494 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-intron | ENST00000517451 | ENST00000505649 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000519549 | ENST00000295897 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000519549 | ENST00000415165 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000519549 | ENST00000503124 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000519549 | ENST00000509063 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-5UTR | ENST00000519549 | ENST00000401494 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
| intron-intron | ENST00000519549 | ENST00000505649 | ABLIM3 | chr5 | 148534150 | - | ALB | chr4 | 74270030 | + |
Top |
FusionProtFeatures for ABLIM3_ALB |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ABLIM3 | ALB |