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Fusion gene ID: 2752 |
FusionGeneSummary for ARMC2_ARMC2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ARMC2_ARMC2 | Fusion gene ID: 2752 | Hgene | Tgene | Gene symbol | ARMC2 | ARMC2 | Gene ID | 84071 | 84071 |
| Gene name | armadillo repeat containing 2 | armadillo repeat containing 2 | |
| Synonyms | bA787I22.1 | bA787I22.1 | |
| Cytomap | 6q21 | 6q21 | |
| Type of gene | protein-coding | protein-coding | |
| Description | armadillo repeat-containing protein 2 | armadillo repeat-containing protein 2 | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | Q8NEN0 | Q8NEN0 | |
| Ensembl transtripts involved in fusion gene | ENST00000368972, ENST00000392644, ENST00000481850, | ENST00000368972, ENST00000392644, ENST00000481850, | |
| Fusion gene scores | * DoF score | 3 X 3 X 2=18 | 11 X 10 X 3=330 |
| # samples | 3 | 10 | |
| ** MAII score | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(10/330*10)=-1.72246602447109 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ARMC2 [Title/Abstract] AND ARMC2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | AW892942 | ARMC2 | chr6 | 109175427 | - | ARMC2 | chr6 | 109197554 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-intron | ENST00000368972 | ENST00000368972 | ARMC2 | chr6 | 109175427 | - | ARMC2 | chr6 | 109197554 | - |
| intron-intron | ENST00000368972 | ENST00000392644 | ARMC2 | chr6 | 109175427 | - | ARMC2 | chr6 | 109197554 | - |
| intron-intron | ENST00000368972 | ENST00000481850 | ARMC2 | chr6 | 109175427 | - | ARMC2 | chr6 | 109197554 | - |
| intron-intron | ENST00000392644 | ENST00000368972 | ARMC2 | chr6 | 109175427 | - | ARMC2 | chr6 | 109197554 | - |
| intron-intron | ENST00000392644 | ENST00000392644 | ARMC2 | chr6 | 109175427 | - | ARMC2 | chr6 | 109197554 | - |
| intron-intron | ENST00000392644 | ENST00000481850 | ARMC2 | chr6 | 109175427 | - | ARMC2 | chr6 | 109197554 | - |
| intron-intron | ENST00000481850 | ENST00000368972 | ARMC2 | chr6 | 109175427 | - | ARMC2 | chr6 | 109197554 | - |
| intron-intron | ENST00000481850 | ENST00000392644 | ARMC2 | chr6 | 109175427 | - | ARMC2 | chr6 | 109197554 | - |
| intron-intron | ENST00000481850 | ENST00000481850 | ARMC2 | chr6 | 109175427 | - | ARMC2 | chr6 | 109197554 | - |
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FusionProtFeatures for ARMC2_ARMC2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ARMC2 | ARMC2 |