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Fusion gene ID: 2733 |
FusionGeneSummary for ARL5B_ARL5B |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ARL5B_ARL5B | Fusion gene ID: 2733 | Hgene | Tgene | Gene symbol | ARL5B | ARL5B | Gene ID | 221079 | 221079 |
| Gene name | ADP ribosylation factor like GTPase 5B | ADP ribosylation factor like GTPase 5B | |
| Synonyms | ARL8 | ARL8 | |
| Cytomap | 10p12.31 | 10p12.31 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ADP-ribosylation factor-like protein 5BADP-ribosylation factor-like 5BADP-ribosylation factor-like 8ADP-ribosylation factor-like protein 8ADP-ribosylation-like factor 8 | ADP-ribosylation factor-like protein 5BADP-ribosylation factor-like 5BADP-ribosylation factor-like 8ADP-ribosylation factor-like protein 8ADP-ribosylation-like factor 8 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q96KC2 | Q96KC2 | |
| Ensembl transtripts involved in fusion gene | ENST00000377275, | ENST00000377275, | |
| Fusion gene scores | * DoF score | 3 X 4 X 3=36 | 2 X 2 X 2=8 |
| # samples | 4 | 3 | |
| ** MAII score | log2(4/36*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(3/8*10)=1.90689059560852 | |
| Context | PubMed: ARL5B [Title/Abstract] AND ARL5B [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BE694671 | ARL5B | chr10 | 18968036 | - | ARL5B | chr10 | 18968106 | + | ||
| ChiTaRS3.1 | BE093787 | ARL5B | chr10 | 18968035 | - | ARL5B | chr10 | 18968106 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-3UTR | ENST00000377275 | ENST00000377275 | ARL5B | chr10 | 18968036 | - | ARL5B | chr10 | 18968106 | + |
| 3UTR-3UTR | ENST00000377275 | ENST00000377275 | ARL5B | chr10 | 18968035 | - | ARL5B | chr10 | 18968106 | + |
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FusionProtFeatures for ARL5B_ARL5B |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ARL5B | ARL5B |