|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 27154 |
FusionGeneSummary for PIGT_CTNNA2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PIGT_CTNNA2 | Fusion gene ID: 27154 | Hgene | Tgene | Gene symbol | PIGT | CTNNA2 | Gene ID | 51604 | 1496 |
| Gene name | phosphatidylinositol glycan anchor biosynthesis class T | catenin alpha 2 | |
| Synonyms | CGI-06|MCAHS3|NDAP|PNH2 | CAP-R|CAPR|CT114|CTNR | |
| Cytomap | 20q13.12 | 2p12 | |
| Type of gene | protein-coding | protein-coding | |
| Description | GPI transamidase component PIG-TGPI transamidase subunitneurotrophin-regulated neuronal development-associated proteinphosphatidylinositol-glycan biosynthesis class T protein | catenin alpha-2alpha-N-cateninalpha-catenin-related proteincadherin-associated protein, relatedcancer/testis antigen 114catenin (cadherin-associated protein), alpha 2 | |
| Modification date | 20180523 | 20180522 | |
| UniProtAcc | Q969N2 | P26232 | |
| Ensembl transtripts involved in fusion gene | ENST00000279036, ENST00000279035, ENST00000372689, ENST00000545755, ENST00000535404, ENST00000341555, ENST00000543458, | ENST00000466387, ENST00000496558, ENST00000361291, ENST00000402739, ENST00000540488, ENST00000541047, ENST00000343114, ENST00000496251, ENST00000409266, | |
| Fusion gene scores | * DoF score | 4 X 4 X 2=32 | 15 X 12 X 9=1620 |
| # samples | 4 | 15 | |
| ** MAII score | log2(4/32*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(15/1620*10)=-3.43295940727611 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: PIGT [Title/Abstract] AND CTNNA2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BE938441 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000279036 | ENST00000466387 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000279036 | ENST00000496558 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000279036 | ENST00000361291 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000279036 | ENST00000402739 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000279036 | ENST00000540488 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000279036 | ENST00000541047 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000279036 | ENST00000343114 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000279036 | ENST00000496251 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000279036 | ENST00000409266 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000279035 | ENST00000466387 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000279035 | ENST00000496558 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000279035 | ENST00000361291 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000279035 | ENST00000402739 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000279035 | ENST00000540488 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000279035 | ENST00000541047 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000279035 | ENST00000343114 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000279035 | ENST00000496251 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000279035 | ENST00000409266 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000372689 | ENST00000466387 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000372689 | ENST00000496558 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000372689 | ENST00000361291 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000372689 | ENST00000402739 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000372689 | ENST00000540488 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000372689 | ENST00000541047 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000372689 | ENST00000343114 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000372689 | ENST00000496251 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000372689 | ENST00000409266 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| intron-intron | ENST00000545755 | ENST00000466387 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| intron-intron | ENST00000545755 | ENST00000496558 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| intron-intron | ENST00000545755 | ENST00000361291 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| intron-intron | ENST00000545755 | ENST00000402739 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| intron-intron | ENST00000545755 | ENST00000540488 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| intron-intron | ENST00000545755 | ENST00000541047 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| intron-intron | ENST00000545755 | ENST00000343114 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| intron-intron | ENST00000545755 | ENST00000496251 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| intron-intron | ENST00000545755 | ENST00000409266 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| intron-intron | ENST00000535404 | ENST00000466387 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| intron-intron | ENST00000535404 | ENST00000496558 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| intron-intron | ENST00000535404 | ENST00000361291 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| intron-intron | ENST00000535404 | ENST00000402739 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| intron-intron | ENST00000535404 | ENST00000540488 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| intron-intron | ENST00000535404 | ENST00000541047 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| intron-intron | ENST00000535404 | ENST00000343114 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| intron-intron | ENST00000535404 | ENST00000496251 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| intron-intron | ENST00000535404 | ENST00000409266 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| intron-intron | ENST00000341555 | ENST00000466387 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| intron-intron | ENST00000341555 | ENST00000496558 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| intron-intron | ENST00000341555 | ENST00000361291 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| intron-intron | ENST00000341555 | ENST00000402739 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| intron-intron | ENST00000341555 | ENST00000540488 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| intron-intron | ENST00000341555 | ENST00000541047 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| intron-intron | ENST00000341555 | ENST00000343114 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| intron-intron | ENST00000341555 | ENST00000496251 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| intron-intron | ENST00000341555 | ENST00000409266 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000543458 | ENST00000466387 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000543458 | ENST00000496558 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000543458 | ENST00000361291 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000543458 | ENST00000402739 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000543458 | ENST00000540488 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000543458 | ENST00000541047 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000543458 | ENST00000343114 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000543458 | ENST00000496251 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
| 5CDS-intron | ENST00000543458 | ENST00000409266 | PIGT | chr20 | 44048017 | + | CTNNA2 | chr2 | 80392188 | - |
Top |
FusionProtFeatures for PIGT_CTNNA2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PIGT | CTNNA2 |