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Fusion gene ID: 26590 |
FusionGeneSummary for PDXDC2P_WDR88 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PDXDC2P_WDR88 | Fusion gene ID: 26590 | Hgene | Tgene | Gene symbol | PDXDC2P | WDR88 | Gene ID | 109731405 | 126248 |
| Gene name | pyridoxal dependent decarboxylase domain containing 2, pseudogene | WD repeat domain 88 | |
| Synonyms | PDXDC2 | PQWD | |
| Cytomap | - | 19q13.11 | |
| Type of gene | pseudo | protein-coding | |
| Description | pyridoxal-dependent decarboxylase domain containing 2 | WD repeat-containing protein 88PQQ repeat and WD repeat domain containingPQQ repeat and WD repeat-containing protein | |
| Modification date | 20180329 | 20180519 | |
| UniProtAcc | Q6ZMY6 | ||
| Ensembl transtripts involved in fusion gene | ENST00000531894, ENST00000525173, | ENST00000592765, ENST00000361680, ENST00000355868, | |
| Fusion gene scores | * DoF score | 3 X 3 X 3=27 | 3 X 3 X 3=27 |
| # samples | 3 | 3 | |
| ** MAII score | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: PDXDC2P [Title/Abstract] AND WDR88 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | LIHC | TCGA-XR-A8TG-01A | PDXDC2P | chr16 | 70016253 | - | WDR88 | chr19 | 33628583 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5UTR-3CDS | ENST00000531894 | ENST00000592765 | PDXDC2P | chr16 | 70016253 | - | WDR88 | chr19 | 33628583 | + |
| 5UTR-3CDS | ENST00000531894 | ENST00000361680 | PDXDC2P | chr16 | 70016253 | - | WDR88 | chr19 | 33628583 | + |
| 5UTR-3CDS | ENST00000531894 | ENST00000355868 | PDXDC2P | chr16 | 70016253 | - | WDR88 | chr19 | 33628583 | + |
| intron-3CDS | ENST00000525173 | ENST00000592765 | PDXDC2P | chr16 | 70016253 | - | WDR88 | chr19 | 33628583 | + |
| intron-3CDS | ENST00000525173 | ENST00000361680 | PDXDC2P | chr16 | 70016253 | - | WDR88 | chr19 | 33628583 | + |
| intron-3CDS | ENST00000525173 | ENST00000355868 | PDXDC2P | chr16 | 70016253 | - | WDR88 | chr19 | 33628583 | + |
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FusionProtFeatures for PDXDC2P_WDR88 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PDXDC2P | WDR88 |