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Fusion gene ID: 26233 |
FusionGeneSummary for PCID2_GRTP1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PCID2_GRTP1 | Fusion gene ID: 26233 | Hgene | Tgene | Gene symbol | PCID2 | GRTP1 | Gene ID | 55795 | 79774 |
| Gene name | PCI domain containing 2 | growth hormone regulated TBC protein 1 | |
| Synonyms | F10 | TBC1D6 | |
| Cytomap | 13q34 | 13q34 | |
| Type of gene | protein-coding | protein-coding | |
| Description | PCI domain-containing protein 2CSN12-like protein | growth hormone-regulated TBC protein 1TBC1 domain family member 6 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q5JVF3 | Q5TC63 | |
| Ensembl transtripts involved in fusion gene | ENST00000337344, ENST00000375477, ENST00000375479, ENST00000493650, ENST00000375459, ENST00000246505, ENST00000375457, | ENST00000375431, ENST00000326039, ENST00000375430, ENST00000476439, | |
| Fusion gene scores | * DoF score | 5 X 3 X 4=60 | 1 X 1 X 1=1 |
| # samples | 4 | 1 | |
| ** MAII score | log2(4/60*10)=-0.584962500721156 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: PCID2 [Title/Abstract] AND GRTP1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | LUSC | TCGA-56-A4ZK-01A | PCID2 | chr13 | 113862913 | - | GRTP1 | chr13 | 114018225 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000337344 | ENST00000375431 | PCID2 | chr13 | 113862913 | - | GRTP1 | chr13 | 114018225 | - |
| 5CDS-intron | ENST00000337344 | ENST00000326039 | PCID2 | chr13 | 113862913 | - | GRTP1 | chr13 | 114018225 | - |
| 5CDS-intron | ENST00000337344 | ENST00000375430 | PCID2 | chr13 | 113862913 | - | GRTP1 | chr13 | 114018225 | - |
| 5CDS-5UTR | ENST00000337344 | ENST00000476439 | PCID2 | chr13 | 113862913 | - | GRTP1 | chr13 | 114018225 | - |
| Frame-shift | ENST00000375477 | ENST00000375431 | PCID2 | chr13 | 113862913 | - | GRTP1 | chr13 | 114018225 | - |
| 5CDS-intron | ENST00000375477 | ENST00000326039 | PCID2 | chr13 | 113862913 | - | GRTP1 | chr13 | 114018225 | - |
| 5CDS-intron | ENST00000375477 | ENST00000375430 | PCID2 | chr13 | 113862913 | - | GRTP1 | chr13 | 114018225 | - |
| 5CDS-5UTR | ENST00000375477 | ENST00000476439 | PCID2 | chr13 | 113862913 | - | GRTP1 | chr13 | 114018225 | - |
| Frame-shift | ENST00000375479 | ENST00000375431 | PCID2 | chr13 | 113862913 | - | GRTP1 | chr13 | 114018225 | - |
| 5CDS-intron | ENST00000375479 | ENST00000326039 | PCID2 | chr13 | 113862913 | - | GRTP1 | chr13 | 114018225 | - |
| 5CDS-intron | ENST00000375479 | ENST00000375430 | PCID2 | chr13 | 113862913 | - | GRTP1 | chr13 | 114018225 | - |
| 5CDS-5UTR | ENST00000375479 | ENST00000476439 | PCID2 | chr13 | 113862913 | - | GRTP1 | chr13 | 114018225 | - |
| intron-3CDS | ENST00000493650 | ENST00000375431 | PCID2 | chr13 | 113862913 | - | GRTP1 | chr13 | 114018225 | - |
| intron-intron | ENST00000493650 | ENST00000326039 | PCID2 | chr13 | 113862913 | - | GRTP1 | chr13 | 114018225 | - |
| intron-intron | ENST00000493650 | ENST00000375430 | PCID2 | chr13 | 113862913 | - | GRTP1 | chr13 | 114018225 | - |
| intron-5UTR | ENST00000493650 | ENST00000476439 | PCID2 | chr13 | 113862913 | - | GRTP1 | chr13 | 114018225 | - |
| intron-3CDS | ENST00000375459 | ENST00000375431 | PCID2 | chr13 | 113862913 | - | GRTP1 | chr13 | 114018225 | - |
| intron-intron | ENST00000375459 | ENST00000326039 | PCID2 | chr13 | 113862913 | - | GRTP1 | chr13 | 114018225 | - |
| intron-intron | ENST00000375459 | ENST00000375430 | PCID2 | chr13 | 113862913 | - | GRTP1 | chr13 | 114018225 | - |
| intron-5UTR | ENST00000375459 | ENST00000476439 | PCID2 | chr13 | 113862913 | - | GRTP1 | chr13 | 114018225 | - |
| Frame-shift | ENST00000246505 | ENST00000375431 | PCID2 | chr13 | 113862913 | - | GRTP1 | chr13 | 114018225 | - |
| 5CDS-intron | ENST00000246505 | ENST00000326039 | PCID2 | chr13 | 113862913 | - | GRTP1 | chr13 | 114018225 | - |
| 5CDS-intron | ENST00000246505 | ENST00000375430 | PCID2 | chr13 | 113862913 | - | GRTP1 | chr13 | 114018225 | - |
| 5CDS-5UTR | ENST00000246505 | ENST00000476439 | PCID2 | chr13 | 113862913 | - | GRTP1 | chr13 | 114018225 | - |
| intron-3CDS | ENST00000375457 | ENST00000375431 | PCID2 | chr13 | 113862913 | - | GRTP1 | chr13 | 114018225 | - |
| intron-intron | ENST00000375457 | ENST00000326039 | PCID2 | chr13 | 113862913 | - | GRTP1 | chr13 | 114018225 | - |
| intron-intron | ENST00000375457 | ENST00000375430 | PCID2 | chr13 | 113862913 | - | GRTP1 | chr13 | 114018225 | - |
| intron-5UTR | ENST00000375457 | ENST00000476439 | PCID2 | chr13 | 113862913 | - | GRTP1 | chr13 | 114018225 | - |
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FusionProtFeatures for PCID2_GRTP1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PCID2 | GRTP1 |