|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 26229 |
FusionGeneSummary for PCGF3_STAG3L3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PCGF3_STAG3L3 | Fusion gene ID: 26229 | Hgene | Tgene | Gene symbol | PCGF3 | STAG3L3 | Gene ID | 10336 | 442578 |
| Gene name | polycomb group ring finger 3 | stromal antigen 3-like 3 (pseudogene) | |
| Synonyms | DONG1|RNF3|RNF3A | STAG3L1|STAG3L2|STAG3L3P | |
| Cytomap | 4p16.3 | 7q11.23 | |
| Type of gene | protein-coding | pseudo | |
| Description | polycomb group RING finger protein 3RING finger protein 3Aring finger protein 3 | STAG3-like protein 3stromal antigen 3 pseudogene | |
| Modification date | 20180523 | 20180329 | |
| UniProtAcc | Q3KNV8 | ||
| Ensembl transtripts involved in fusion gene | ENST00000362003, ENST00000400151, ENST00000482726, ENST00000470161, ENST00000521023, ENST00000505655, | ENST00000428423, | |
| Fusion gene scores | * DoF score | 11 X 7 X 7=539 | 1 X 1 X 1=1 |
| # samples | 11 | 1 | |
| ** MAII score | log2(11/539*10)=-2.29278174922785 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: PCGF3 [Title/Abstract] AND STAG3L3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BE835063 | PCGF3 | chr4 | 760473 | + | STAG3L3 | chr7 | 72448304 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-intron | ENST00000362003 | ENST00000428423 | PCGF3 | chr4 | 760473 | + | STAG3L3 | chr7 | 72448304 | - |
| intron-intron | ENST00000400151 | ENST00000428423 | PCGF3 | chr4 | 760473 | + | STAG3L3 | chr7 | 72448304 | - |
| intron-intron | ENST00000482726 | ENST00000428423 | PCGF3 | chr4 | 760473 | + | STAG3L3 | chr7 | 72448304 | - |
| intron-intron | ENST00000470161 | ENST00000428423 | PCGF3 | chr4 | 760473 | + | STAG3L3 | chr7 | 72448304 | - |
| 3UTR-intron | ENST00000521023 | ENST00000428423 | PCGF3 | chr4 | 760473 | + | STAG3L3 | chr7 | 72448304 | - |
| 3UTR-intron | ENST00000505655 | ENST00000428423 | PCGF3 | chr4 | 760473 | + | STAG3L3 | chr7 | 72448304 | - |
Top |
FusionProtFeatures for PCGF3_STAG3L3 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PCGF3 | STAG3L3 |