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Fusion gene ID: 26194 |
FusionGeneSummary for PCDH7_PCDH7 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PCDH7_PCDH7 | Fusion gene ID: 26194 | Hgene | Tgene | Gene symbol | PCDH7 | PCDH7 | Gene ID | 5099 | 5099 |
| Gene name | protocadherin 7 | protocadherin 7 | |
| Synonyms | BH-Pcdh|BHPCDH|PPP1R120 | BH-Pcdh|BHPCDH|PPP1R120 | |
| Cytomap | 4p15.1 | 4p15.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | protocadherin-7BH-protocadherin (brain-heart)brain-heart protocadherinprotein phosphatase 1, regulatory subunit 120 | protocadherin-7BH-protocadherin (brain-heart)brain-heart protocadherinprotein phosphatase 1, regulatory subunit 120 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | O60245 | O60245 | |
| Ensembl transtripts involved in fusion gene | ENST00000543491, ENST00000509925, ENST00000361762, | ENST00000543491, ENST00000509925, ENST00000361762, | |
| Fusion gene scores | * DoF score | 4 X 5 X 1=20 | 1 X 2 X 1=2 |
| # samples | 5 | 2 | |
| ** MAII score | log2(5/20*10)=1.32192809488736 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(2/2*10)=3.32192809488736 | |
| Context | PubMed: PCDH7 [Title/Abstract] AND PCDH7 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | AA730641 | PCDH7 | chr4 | 31120165 | + | PCDH7 | chr4 | 31120027 | - | ||
| ChiTaRS3.1 | AA468303 | PCDH7 | chr4 | 30896041 | + | PCDH7 | chr4 | 30895949 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-intron | ENST00000543491 | ENST00000543491 | PCDH7 | chr4 | 31120165 | + | PCDH7 | chr4 | 31120027 | - |
| intron-intron | ENST00000543491 | ENST00000509925 | PCDH7 | chr4 | 31120165 | + | PCDH7 | chr4 | 31120027 | - |
| intron-intron | ENST00000543491 | ENST00000361762 | PCDH7 | chr4 | 31120165 | + | PCDH7 | chr4 | 31120027 | - |
| intron-intron | ENST00000509925 | ENST00000543491 | PCDH7 | chr4 | 31120165 | + | PCDH7 | chr4 | 31120027 | - |
| intron-intron | ENST00000509925 | ENST00000509925 | PCDH7 | chr4 | 31120165 | + | PCDH7 | chr4 | 31120027 | - |
| intron-intron | ENST00000509925 | ENST00000361762 | PCDH7 | chr4 | 31120165 | + | PCDH7 | chr4 | 31120027 | - |
| intron-intron | ENST00000361762 | ENST00000543491 | PCDH7 | chr4 | 31120165 | + | PCDH7 | chr4 | 31120027 | - |
| intron-intron | ENST00000361762 | ENST00000509925 | PCDH7 | chr4 | 31120165 | + | PCDH7 | chr4 | 31120027 | - |
| intron-intron | ENST00000361762 | ENST00000361762 | PCDH7 | chr4 | 31120165 | + | PCDH7 | chr4 | 31120027 | - |
| intron-intron | ENST00000543491 | ENST00000543491 | PCDH7 | chr4 | 30896041 | + | PCDH7 | chr4 | 30895949 | - |
| intron-intron | ENST00000543491 | ENST00000509925 | PCDH7 | chr4 | 30896041 | + | PCDH7 | chr4 | 30895949 | - |
| intron-intron | ENST00000543491 | ENST00000361762 | PCDH7 | chr4 | 30896041 | + | PCDH7 | chr4 | 30895949 | - |
| intron-intron | ENST00000509925 | ENST00000543491 | PCDH7 | chr4 | 30896041 | + | PCDH7 | chr4 | 30895949 | - |
| intron-intron | ENST00000509925 | ENST00000509925 | PCDH7 | chr4 | 30896041 | + | PCDH7 | chr4 | 30895949 | - |
| intron-intron | ENST00000509925 | ENST00000361762 | PCDH7 | chr4 | 30896041 | + | PCDH7 | chr4 | 30895949 | - |
| intron-intron | ENST00000361762 | ENST00000543491 | PCDH7 | chr4 | 30896041 | + | PCDH7 | chr4 | 30895949 | - |
| intron-intron | ENST00000361762 | ENST00000509925 | PCDH7 | chr4 | 30896041 | + | PCDH7 | chr4 | 30895949 | - |
| intron-intron | ENST00000361762 | ENST00000361762 | PCDH7 | chr4 | 30896041 | + | PCDH7 | chr4 | 30895949 | - |
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FusionProtFeatures for PCDH7_PCDH7 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PCDH7 | PCDH7 |