|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 26106 |
FusionGeneSummary for PBRM1_GLT8D1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PBRM1_GLT8D1 | Fusion gene ID: 26106 | Hgene | Tgene | Gene symbol | PBRM1 | GLT8D1 | Gene ID | 55193 | 55830 |
| Gene name | polybromo 1 | glycosyltransferase 8 domain containing 1 | |
| Synonyms | BAF180|PB1 | AD-017|MSTP139 | |
| Cytomap | 3p21.1 | 3p21.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | protein polybromo-1BRG1-associated factor 180polybromo-1D | glycosyltransferase 8 domain-containing protein 1glycosyltransferase AD-017 | |
| Modification date | 20180523 | 20180526 | |
| UniProtAcc | Q86U86 | Q68CQ7 | |
| Ensembl transtripts involved in fusion gene | ENST00000356770, ENST00000394830, ENST00000296302, ENST00000337303, ENST00000410007, ENST00000409057, ENST00000409114, ENST00000409767, | ENST00000478968, ENST00000394783, ENST00000407584, ENST00000266014, ENST00000491606, ENST00000463827, | |
| Fusion gene scores | * DoF score | 9 X 6 X 9=486 | 4 X 3 X 4=48 |
| # samples | 10 | 4 | |
| ** MAII score | log2(10/486*10)=-2.28095631383106 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/48*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: PBRM1 [Title/Abstract] AND GLT8D1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | HNSC | TCGA-QK-A6VC-01A | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-5UTR | ENST00000356770 | ENST00000478968 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000356770 | ENST00000394783 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000356770 | ENST00000407584 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000356770 | ENST00000266014 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000356770 | ENST00000491606 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-intron | ENST00000356770 | ENST00000463827 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000394830 | ENST00000478968 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000394830 | ENST00000394783 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000394830 | ENST00000407584 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000394830 | ENST00000266014 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000394830 | ENST00000491606 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-intron | ENST00000394830 | ENST00000463827 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000296302 | ENST00000478968 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000296302 | ENST00000394783 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000296302 | ENST00000407584 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000296302 | ENST00000266014 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000296302 | ENST00000491606 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-intron | ENST00000296302 | ENST00000463827 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000337303 | ENST00000478968 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000337303 | ENST00000394783 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000337303 | ENST00000407584 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000337303 | ENST00000266014 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000337303 | ENST00000491606 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-intron | ENST00000337303 | ENST00000463827 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000410007 | ENST00000478968 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000410007 | ENST00000394783 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000410007 | ENST00000407584 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000410007 | ENST00000266014 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000410007 | ENST00000491606 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-intron | ENST00000410007 | ENST00000463827 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000409057 | ENST00000478968 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000409057 | ENST00000394783 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000409057 | ENST00000407584 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000409057 | ENST00000266014 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000409057 | ENST00000491606 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-intron | ENST00000409057 | ENST00000463827 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000409114 | ENST00000478968 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000409114 | ENST00000394783 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000409114 | ENST00000407584 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000409114 | ENST00000266014 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000409114 | ENST00000491606 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-intron | ENST00000409114 | ENST00000463827 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000409767 | ENST00000478968 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000409767 | ENST00000394783 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000409767 | ENST00000407584 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000409767 | ENST00000266014 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-5UTR | ENST00000409767 | ENST00000491606 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
| 5CDS-intron | ENST00000409767 | ENST00000463827 | PBRM1 | chr3 | 52712516 | - | GLT8D1 | chr3 | 52734512 | - |
Top |
FusionProtFeatures for PBRM1_GLT8D1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PBRM1 | GLT8D1 |