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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDrugs

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RelatedDiseases

Fusion gene ID: 2603

FusionGeneSummary for ARID1A_ARID1A

check button Fusion gene summary
Fusion gene informationFusion gene name: ARID1A_ARID1A
Fusion gene ID: 2603
HgeneTgene
Gene symbol

ARID1A

ARID1A

Gene ID

8289

8289

Gene nameAT-rich interaction domain 1AAT-rich interaction domain 1A
SynonymsB120|BAF250|BAF250a|BM029|C1orf4|CSS2|ELD|MRD14|OSA1|P270|SMARCF1|hELD|hOSA1B120|BAF250|BAF250a|BM029|C1orf4|CSS2|ELD|MRD14|OSA1|P270|SMARCF1|hELD|hOSA1
Cytomap

1p36.11

1p36.11

Type of geneprotein-codingprotein-coding
DescriptionAT-rich interactive domain-containing protein 1AARID domain-containing protein 1AAT rich interactive domain 1A (SWI-like)BRG1-associated factor 250aOSA1 nuclear proteinSWI-like proteinSWI/SNF complex protein p270SWI/SNF-related, matrix-associated, AT-rich interactive domain-containing protein 1AARID domain-containing protein 1AAT rich interactive domain 1A (SWI-like)BRG1-associated factor 250aOSA1 nuclear proteinSWI-like proteinSWI/SNF complex protein p270SWI/SNF-related, matrix-associated,
Modification date2018051920180519
UniProtAcc

O14497

O14497

Ensembl transtripts involved in fusion geneENST00000324856, ENST00000457599, 
ENST00000374152, ENST00000540690, 
ENST00000324856, ENST00000457599, 
ENST00000374152, ENST00000540690, 
Fusion gene scores* DoF score21 X 13 X 13=35497 X 11 X 3=231
# samples 3111
** MAII scorelog2(31/3549*10)=-3.51707245378671
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/231*10)=-1.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ARID1A [Title/Abstract] AND ARID1A [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationTumor suppressor gene involved fusion gene, in-frame but not retained their domain.
Tumor suppressor gene involved fusion gene, retained protein feature but frameshift.
DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneARID1A

GO:0006337

nucleosome disassembly

8895581

HgeneARID1A

GO:0006338

chromatin remodeling

11726552

HgeneARID1A

GO:0030520

intracellular estrogen receptor signaling pathway

12200431

HgeneARID1A

GO:0030521

androgen receptor signaling pathway

12200431

HgeneARID1A

GO:0042921

glucocorticoid receptor signaling pathway

12200431

HgeneARID1A

GO:0045893

positive regulation of transcription, DNA-templated

12200431

TgeneARID1A

GO:0006337

nucleosome disassembly

8895581

TgeneARID1A

GO:0006338

chromatin remodeling

11726552

TgeneARID1A

GO:0030520

intracellular estrogen receptor signaling pathway

12200431

TgeneARID1A

GO:0030521

androgen receptor signaling pathway

12200431

TgeneARID1A

GO:0042921

glucocorticoid receptor signaling pathway

12200431

TgeneARID1A

GO:0045893

positive regulation of transcription, DNA-templated

12200431


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS3.1CV314170ARID1Achr1

27106617

-ARID1Achr1

27106589

+
ChiTaRS3.1BF808164ARID1Achr1

27059283

+ARID1Achr1

27056142

+
ChiTaRS3.1BF990251ARID1Achr1

27101155

-ARID1Achr1

27101280

+
ChiTaRS3.1BF759670ARID1Achr1

27105691

+ARID1Achr1

27105502

-
ChiTaRS3.1AW847910ARID1Achr1

27057829

-ARID1Achr1

27094341

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000324856ENST00000324856ARID1Achr1

27106617

-ARID1Achr1

27106589

+
Frame-shiftENST00000324856ENST00000457599ARID1Achr1

27106617

-ARID1Achr1

27106589

+
Frame-shiftENST00000324856ENST00000374152ARID1Achr1

27106617

-ARID1Achr1

27106589

+
Frame-shiftENST00000324856ENST00000540690ARID1Achr1

27106617

-ARID1Achr1

27106589

+
Frame-shiftENST00000457599ENST00000324856ARID1Achr1

27106617

-ARID1Achr1

27106589

+
Frame-shiftENST00000457599ENST00000457599ARID1Achr1

27106617

-ARID1Achr1

27106589

+
Frame-shiftENST00000457599ENST00000374152ARID1Achr1

27106617

-ARID1Achr1

27106589

+
Frame-shiftENST00000457599ENST00000540690ARID1Achr1

27106617

-ARID1Achr1

27106589

+
Frame-shiftENST00000374152ENST00000324856ARID1Achr1

27106617

-ARID1Achr1

27106589

+
Frame-shiftENST00000374152ENST00000457599ARID1Achr1

27106617

-ARID1Achr1

27106589

+
In-frameENST00000374152ENST00000374152ARID1Achr1

27106617

-ARID1Achr1

27106589

+
Frame-shiftENST00000374152ENST00000540690ARID1Achr1

27106617

-ARID1Achr1

27106589

+
Frame-shiftENST00000540690ENST00000324856ARID1Achr1

27106617

-ARID1Achr1

27106589

+
Frame-shiftENST00000540690ENST00000457599ARID1Achr1

27106617

-ARID1Achr1

27106589

+
Frame-shiftENST00000540690ENST00000374152ARID1Achr1

27106617

-ARID1Achr1

27106589

+
Frame-shiftENST00000540690ENST00000540690ARID1Achr1

27106617

-ARID1Achr1

27106589

+
In-frameENST00000324856ENST00000324856ARID1Achr1

27059283

+ARID1Achr1

27056142

+
In-frameENST00000324856ENST00000457599ARID1Achr1

27059283

+ARID1Achr1

27056142

+
5CDS-5UTRENST00000324856ENST00000374152ARID1Achr1

27059283

+ARID1Achr1

27056142

+
5CDS-intronENST00000324856ENST00000540690ARID1Achr1

27059283

+ARID1Achr1

27056142

+
In-frameENST00000457599ENST00000324856ARID1Achr1

27059283

+ARID1Achr1

27056142

+
In-frameENST00000457599ENST00000457599ARID1Achr1

27059283

+ARID1Achr1

27056142

+
5CDS-5UTRENST00000457599ENST00000374152ARID1Achr1

27059283

+ARID1Achr1

27056142

+
5CDS-intronENST00000457599ENST00000540690ARID1Achr1

27059283

+ARID1Achr1

27056142

+
In-frameENST00000374152ENST00000324856ARID1Achr1

27059283

+ARID1Achr1

27056142

+
In-frameENST00000374152ENST00000457599ARID1Achr1

27059283

+ARID1Achr1

27056142

+
5CDS-5UTRENST00000374152ENST00000374152ARID1Achr1

27059283

+ARID1Achr1

27056142

+
5CDS-intronENST00000374152ENST00000540690ARID1Achr1

27059283

+ARID1Achr1

27056142

+
intron-3CDSENST00000540690ENST00000324856ARID1Achr1

27059283

+ARID1Achr1

27056142

+
intron-3CDSENST00000540690ENST00000457599ARID1Achr1

27059283

+ARID1Achr1

27056142

+
intron-5UTRENST00000540690ENST00000374152ARID1Achr1

27059283

+ARID1Achr1

27056142

+
intron-intronENST00000540690ENST00000540690ARID1Achr1

27059283

+ARID1Achr1

27056142

+
Frame-shiftENST00000324856ENST00000324856ARID1Achr1

27101155

-ARID1Achr1

27101280

+
5CDS-intronENST00000324856ENST00000457599ARID1Achr1

27101155

-ARID1Achr1

27101280

+
5CDS-intronENST00000324856ENST00000374152ARID1Achr1

27101155

-ARID1Achr1

27101280

+
5CDS-intronENST00000324856ENST00000540690ARID1Achr1

27101155

-ARID1Achr1

27101280

+
intron-3CDSENST00000457599ENST00000324856ARID1Achr1

27101155

-ARID1Achr1

27101280

+
intron-intronENST00000457599ENST00000457599ARID1Achr1

27101155

-ARID1Achr1

27101280

+
intron-intronENST00000457599ENST00000374152ARID1Achr1

27101155

-ARID1Achr1

27101280

+
intron-intronENST00000457599ENST00000540690ARID1Achr1

27101155

-ARID1Achr1

27101280

+
Frame-shiftENST00000374152ENST00000324856ARID1Achr1

27101155

-ARID1Achr1

27101280

+
5CDS-intronENST00000374152ENST00000457599ARID1Achr1

27101155

-ARID1Achr1

27101280

+
5CDS-intronENST00000374152ENST00000374152ARID1Achr1

27101155

-ARID1Achr1

27101280

+
5CDS-intronENST00000374152ENST00000540690ARID1Achr1

27101155

-ARID1Achr1

27101280

+
intron-3CDSENST00000540690ENST00000324856ARID1Achr1

27101155

-ARID1Achr1

27101280

+
intron-intronENST00000540690ENST00000457599ARID1Achr1

27101155

-ARID1Achr1

27101280

+
intron-intronENST00000540690ENST00000374152ARID1Achr1

27101155

-ARID1Achr1

27101280

+
intron-intronENST00000540690ENST00000540690ARID1Achr1

27101155

-ARID1Achr1

27101280

+
5CDS-intronENST00000324856ENST00000324856ARID1Achr1

27105691

+ARID1Achr1

27105502

-
5CDS-intronENST00000324856ENST00000457599ARID1Achr1

27105691

+ARID1Achr1

27105502

-
5CDS-intronENST00000324856ENST00000374152ARID1Achr1

27105691

+ARID1Achr1

27105502

-
5CDS-intronENST00000324856ENST00000540690ARID1Achr1

27105691

+ARID1Achr1

27105502

-
5CDS-intronENST00000457599ENST00000324856ARID1Achr1

27105691

+ARID1Achr1

27105502

-
5CDS-intronENST00000457599ENST00000457599ARID1Achr1

27105691

+ARID1Achr1

27105502

-
5CDS-intronENST00000457599ENST00000374152ARID1Achr1

27105691

+ARID1Achr1

27105502

-
5CDS-intronENST00000457599ENST00000540690ARID1Achr1

27105691

+ARID1Achr1

27105502

-
5CDS-intronENST00000374152ENST00000324856ARID1Achr1

27105691

+ARID1Achr1

27105502

-
5CDS-intronENST00000374152ENST00000457599ARID1Achr1

27105691

+ARID1Achr1

27105502

-
5CDS-intronENST00000374152ENST00000374152ARID1Achr1

27105691

+ARID1Achr1

27105502

-
5CDS-intronENST00000374152ENST00000540690ARID1Achr1

27105691

+ARID1Achr1

27105502

-
5CDS-intronENST00000540690ENST00000324856ARID1Achr1

27105691

+ARID1Achr1

27105502

-
5CDS-intronENST00000540690ENST00000457599ARID1Achr1

27105691

+ARID1Achr1

27105502

-
5CDS-intronENST00000540690ENST00000374152ARID1Achr1

27105691

+ARID1Achr1

27105502

-
5CDS-intronENST00000540690ENST00000540690ARID1Achr1

27105691

+ARID1Achr1

27105502

-
In-frameENST00000324856ENST00000324856ARID1Achr1

27057829

-ARID1Achr1

27094341

+
In-frameENST00000324856ENST00000457599ARID1Achr1

27057829

-ARID1Achr1

27094341

+
In-frameENST00000324856ENST00000374152ARID1Achr1

27057829

-ARID1Achr1

27094341

+
5CDS-intronENST00000324856ENST00000540690ARID1Achr1

27057829

-ARID1Achr1

27094341

+
In-frameENST00000457599ENST00000324856ARID1Achr1

27057829

-ARID1Achr1

27094341

+
In-frameENST00000457599ENST00000457599ARID1Achr1

27057829

-ARID1Achr1

27094341

+
In-frameENST00000457599ENST00000374152ARID1Achr1

27057829

-ARID1Achr1

27094341

+
5CDS-intronENST00000457599ENST00000540690ARID1Achr1

27057829

-ARID1Achr1

27094341

+
In-frameENST00000374152ENST00000324856ARID1Achr1

27057829

-ARID1Achr1

27094341

+
In-frameENST00000374152ENST00000457599ARID1Achr1

27057829

-ARID1Achr1

27094341

+
In-frameENST00000374152ENST00000374152ARID1Achr1

27057829

-ARID1Achr1

27094341

+
5CDS-intronENST00000374152ENST00000540690ARID1Achr1

27057829

-ARID1Achr1

27094341

+
intron-3CDSENST00000540690ENST00000324856ARID1Achr1

27057829

-ARID1Achr1

27094341

+
intron-3CDSENST00000540690ENST00000457599ARID1Achr1

27057829

-ARID1Achr1

27094341

+
intron-3CDSENST00000540690ENST00000374152ARID1Achr1

27057829

-ARID1Achr1

27094341

+
intron-intronENST00000540690ENST00000540690ARID1Achr1

27057829

-ARID1Achr1

27094341

+

Top

FusionProtFeatures for ARID1A_ARID1A


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ARID1A

O14497

ARID1A

O14497


check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneARID1Achr1:27059283chr1:27056142ENST00000324856+420479_4826402286Compositional biasNote=Poly-Gln
HgeneARID1Achr1:27059283chr1:27056142ENST00000324856+420561_5676402286Compositional biasNote=Poly-Gln
HgeneARID1Achr1:27059283chr1:27056142ENST00000457599+420479_4826402069Compositional biasNote=Poly-Gln
HgeneARID1Achr1:27059283chr1:27056142ENST00000457599+420561_5676402069Compositional biasNote=Poly-Gln
HgeneARID1Achr1:27059283chr1:27056142ENST00000324856+420295_2996402286MotifNote=LXXLL
HgeneARID1Achr1:27059283chr1:27056142ENST00000457599+420295_2996402069MotifNote=LXXLL
TgeneARID1Achr1:27057829chr1:27094341ENST00000324856+0201327_1404-1242286Compositional biasNote=Gln-rich
TgeneARID1Achr1:27057829chr1:27094341ENST00000324856+020479_482-1242286Compositional biasNote=Poly-Gln
TgeneARID1Achr1:27057829chr1:27094341ENST00000324856+020561_567-1242286Compositional biasNote=Poly-Gln
TgeneARID1Achr1:27057829chr1:27094341ENST00000324856+020998_1001-1242286Compositional biasNote=Poly-Ser
TgeneARID1Achr1:27057829chr1:27094341ENST00000374152+0191327_1404-951903Compositional biasNote=Gln-rich
TgeneARID1Achr1:27057829chr1:27094341ENST00000374152+019479_482-951903Compositional biasNote=Poly-Gln
TgeneARID1Achr1:27057829chr1:27094341ENST00000374152+019561_567-951903Compositional biasNote=Poly-Gln
TgeneARID1Achr1:27057829chr1:27094341ENST00000374152+019998_1001-951903Compositional biasNote=Poly-Ser
TgeneARID1Achr1:27057829chr1:27094341ENST00000457599+0201327_140402069Compositional biasNote=Gln-rich
TgeneARID1Achr1:27057829chr1:27094341ENST00000457599+020479_48202069Compositional biasNote=Poly-Gln
TgeneARID1Achr1:27057829chr1:27094341ENST00000457599+020561_56702069Compositional biasNote=Poly-Gln
TgeneARID1Achr1:27057829chr1:27094341ENST00000457599+020998_100102069Compositional biasNote=Poly-Ser
TgeneARID1Achr1:27059283chr1:27056142ENST00000324856+0201327_14043792286Compositional biasNote=Gln-rich
TgeneARID1Achr1:27059283chr1:27056142ENST00000324856+020479_4823792286Compositional biasNote=Poly-Gln
TgeneARID1Achr1:27059283chr1:27056142ENST00000324856+020561_5673792286Compositional biasNote=Poly-Gln
TgeneARID1Achr1:27059283chr1:27056142ENST00000324856+020998_10013792286Compositional biasNote=Poly-Ser
TgeneARID1Achr1:27059283chr1:27056142ENST00000374152+0191327_1404-951903Compositional biasNote=Gln-rich
TgeneARID1Achr1:27059283chr1:27056142ENST00000374152+019479_482-951903Compositional biasNote=Poly-Gln
TgeneARID1Achr1:27059283chr1:27056142ENST00000374152+019561_567-951903Compositional biasNote=Poly-Gln
TgeneARID1Achr1:27059283chr1:27056142ENST00000374152+019998_1001-951903Compositional biasNote=Poly-Ser
TgeneARID1Achr1:27059283chr1:27056142ENST00000457599+0201327_14043792069Compositional biasNote=Gln-rich
TgeneARID1Achr1:27059283chr1:27056142ENST00000457599+020479_4823792069Compositional biasNote=Poly-Gln
TgeneARID1Achr1:27059283chr1:27056142ENST00000457599+020561_5673792069Compositional biasNote=Poly-Gln
TgeneARID1Achr1:27059283chr1:27056142ENST00000457599+020998_10013792069Compositional biasNote=Poly-Ser
TgeneARID1Achr1:27057829chr1:27094341ENST00000324856+0201017_1108-1242286DomainARID
TgeneARID1Achr1:27057829chr1:27094341ENST00000374152+0191017_1108-951903DomainARID
TgeneARID1Achr1:27057829chr1:27094341ENST00000457599+0201017_110802069DomainARID
TgeneARID1Achr1:27059283chr1:27056142ENST00000324856+0201017_11083792286DomainARID
TgeneARID1Achr1:27059283chr1:27056142ENST00000374152+0191017_1108-951903DomainARID
TgeneARID1Achr1:27059283chr1:27056142ENST00000457599+0201017_11083792069DomainARID
TgeneARID1Achr1:27057829chr1:27094341ENST00000324856+0201368_1387-1242286MotifNuclear localization signal
TgeneARID1Achr1:27057829chr1:27094341ENST00000324856+0201709_1713-1242286MotifNote=LXXLL
TgeneARID1Achr1:27057829chr1:27094341ENST00000324856+0201967_1971-1242286MotifNote=LXXLL
TgeneARID1Achr1:27057829chr1:27094341ENST00000324856+0202085_2089-1242286MotifNote=LXXLL
TgeneARID1Achr1:27057829chr1:27094341ENST00000324856+020295_299-1242286MotifNote=LXXLL
TgeneARID1Achr1:27057829chr1:27094341ENST00000374152+0191368_1387-951903MotifNuclear localization signal
TgeneARID1Achr1:27057829chr1:27094341ENST00000374152+0191709_1713-951903MotifNote=LXXLL
TgeneARID1Achr1:27057829chr1:27094341ENST00000374152+0191967_1971-951903MotifNote=LXXLL
TgeneARID1Achr1:27057829chr1:27094341ENST00000374152+0192085_2089-951903MotifNote=LXXLL
TgeneARID1Achr1:27057829chr1:27094341ENST00000374152+019295_299-951903MotifNote=LXXLL
TgeneARID1Achr1:27057829chr1:27094341ENST00000457599+0201368_138702069MotifNuclear localization signal
TgeneARID1Achr1:27057829chr1:27094341ENST00000457599+0201709_171302069MotifNote=LXXLL
TgeneARID1Achr1:27057829chr1:27094341ENST00000457599+0201967_197102069MotifNote=LXXLL
TgeneARID1Achr1:27057829chr1:27094341ENST00000457599+0202085_208902069MotifNote=LXXLL
TgeneARID1Achr1:27057829chr1:27094341ENST00000457599+020295_29902069MotifNote=LXXLL
TgeneARID1Achr1:27059283chr1:27056142ENST00000324856+0201368_13873792286MotifNuclear localization signal
TgeneARID1Achr1:27059283chr1:27056142ENST00000324856+0201709_17133792286MotifNote=LXXLL
TgeneARID1Achr1:27059283chr1:27056142ENST00000324856+0201967_19713792286MotifNote=LXXLL
TgeneARID1Achr1:27059283chr1:27056142ENST00000324856+0202085_20893792286MotifNote=LXXLL
TgeneARID1Achr1:27059283chr1:27056142ENST00000374152+0191368_1387-951903MotifNuclear localization signal
TgeneARID1Achr1:27059283chr1:27056142ENST00000374152+0191709_1713-951903MotifNote=LXXLL
TgeneARID1Achr1:27059283chr1:27056142ENST00000374152+0191967_1971-951903MotifNote=LXXLL
TgeneARID1Achr1:27059283chr1:27056142ENST00000374152+0192085_2089-951903MotifNote=LXXLL
TgeneARID1Achr1:27059283chr1:27056142ENST00000374152+019295_299-951903MotifNote=LXXLL
TgeneARID1Achr1:27059283chr1:27056142ENST00000457599+0201368_13873792069MotifNuclear localization signal
TgeneARID1Achr1:27059283chr1:27056142ENST00000457599+0201709_17133792069MotifNote=LXXLL
TgeneARID1Achr1:27059283chr1:27056142ENST00000457599+0201967_19713792069MotifNote=LXXLL
TgeneARID1Achr1:27059283chr1:27056142ENST00000457599+0202085_20893792069MotifNote=LXXLL

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneARID1Achr1:27057829chr1:27094341ENST00000324856+1201327_1404-1242286Compositional biasNote=Gln-rich
HgeneARID1Achr1:27057829chr1:27094341ENST00000324856+120479_482-1242286Compositional biasNote=Poly-Gln
HgeneARID1Achr1:27057829chr1:27094341ENST00000324856+120561_567-1242286Compositional biasNote=Poly-Gln
HgeneARID1Achr1:27057829chr1:27094341ENST00000324856+120998_1001-1242286Compositional biasNote=Poly-Ser
HgeneARID1Achr1:27057829chr1:27094341ENST00000374152+1191327_1404-951903Compositional biasNote=Gln-rich
HgeneARID1Achr1:27057829chr1:27094341ENST00000374152+119479_482-951903Compositional biasNote=Poly-Gln
HgeneARID1Achr1:27057829chr1:27094341ENST00000374152+119561_567-951903Compositional biasNote=Poly-Gln
HgeneARID1Achr1:27057829chr1:27094341ENST00000374152+119998_1001-951903Compositional biasNote=Poly-Ser
HgeneARID1Achr1:27057829chr1:27094341ENST00000457599+1201327_140402069Compositional biasNote=Gln-rich
HgeneARID1Achr1:27057829chr1:27094341ENST00000457599+120479_48202069Compositional biasNote=Poly-Gln
HgeneARID1Achr1:27057829chr1:27094341ENST00000457599+120561_56702069Compositional biasNote=Poly-Gln
HgeneARID1Achr1:27057829chr1:27094341ENST00000457599+120998_100102069Compositional biasNote=Poly-Ser
HgeneARID1Achr1:27059283chr1:27056142ENST00000324856+4201327_14046402286Compositional biasNote=Gln-rich
HgeneARID1Achr1:27059283chr1:27056142ENST00000324856+420998_10016402286Compositional biasNote=Poly-Ser
HgeneARID1Achr1:27059283chr1:27056142ENST00000374152+3191327_14042571903Compositional biasNote=Gln-rich
HgeneARID1Achr1:27059283chr1:27056142ENST00000374152+319479_4822571903Compositional biasNote=Poly-Gln
HgeneARID1Achr1:27059283chr1:27056142ENST00000374152+319561_5672571903Compositional biasNote=Poly-Gln
HgeneARID1Achr1:27059283chr1:27056142ENST00000374152+319998_10012571903Compositional biasNote=Poly-Ser
HgeneARID1Achr1:27059283chr1:27056142ENST00000457599+4201327_14046402069Compositional biasNote=Gln-rich
HgeneARID1Achr1:27059283chr1:27056142ENST00000457599+420998_10016402069Compositional biasNote=Poly-Ser
HgeneARID1Achr1:27057829chr1:27094341ENST00000324856+1201017_1108-1242286DomainARID
HgeneARID1Achr1:27057829chr1:27094341ENST00000374152+1191017_1108-951903DomainARID
HgeneARID1Achr1:27057829chr1:27094341ENST00000457599+1201017_110802069DomainARID
HgeneARID1Achr1:27059283chr1:27056142ENST00000324856+4201017_11086402286DomainARID
HgeneARID1Achr1:27059283chr1:27056142ENST00000374152+3191017_11082571903DomainARID
HgeneARID1Achr1:27059283chr1:27056142ENST00000457599+4201017_11086402069DomainARID
HgeneARID1Achr1:27057829chr1:27094341ENST00000324856+1201368_1387-1242286MotifNuclear localization signal
HgeneARID1Achr1:27057829chr1:27094341ENST00000324856+1201709_1713-1242286MotifNote=LXXLL
HgeneARID1Achr1:27057829chr1:27094341ENST00000324856+1201967_1971-1242286MotifNote=LXXLL
HgeneARID1Achr1:27057829chr1:27094341ENST00000324856+1202085_2089-1242286MotifNote=LXXLL
HgeneARID1Achr1:27057829chr1:27094341ENST00000324856+120295_299-1242286MotifNote=LXXLL
HgeneARID1Achr1:27057829chr1:27094341ENST00000374152+1191368_1387-951903MotifNuclear localization signal
HgeneARID1Achr1:27057829chr1:27094341ENST00000374152+1191709_1713-951903MotifNote=LXXLL
HgeneARID1Achr1:27057829chr1:27094341ENST00000374152+1191967_1971-951903MotifNote=LXXLL
HgeneARID1Achr1:27057829chr1:27094341ENST00000374152+1192085_2089-951903MotifNote=LXXLL
HgeneARID1Achr1:27057829chr1:27094341ENST00000374152+119295_299-951903MotifNote=LXXLL
HgeneARID1Achr1:27057829chr1:27094341ENST00000457599+1201368_138702069MotifNuclear localization signal
HgeneARID1Achr1:27057829chr1:27094341ENST00000457599+1201709_171302069MotifNote=LXXLL
HgeneARID1Achr1:27057829chr1:27094341ENST00000457599+1201967_197102069MotifNote=LXXLL
HgeneARID1Achr1:27057829chr1:27094341ENST00000457599+1202085_208902069MotifNote=LXXLL
HgeneARID1Achr1:27057829chr1:27094341ENST00000457599+120295_29902069MotifNote=LXXLL
HgeneARID1Achr1:27059283chr1:27056142ENST00000324856+4201368_13876402286MotifNuclear localization signal
HgeneARID1Achr1:27059283chr1:27056142ENST00000324856+4201709_17136402286MotifNote=LXXLL
HgeneARID1Achr1:27059283chr1:27056142ENST00000324856+4201967_19716402286MotifNote=LXXLL
HgeneARID1Achr1:27059283chr1:27056142ENST00000324856+4202085_20896402286MotifNote=LXXLL
HgeneARID1Achr1:27059283chr1:27056142ENST00000374152+3191368_13872571903MotifNuclear localization signal
HgeneARID1Achr1:27059283chr1:27056142ENST00000374152+3191709_17132571903MotifNote=LXXLL
HgeneARID1Achr1:27059283chr1:27056142ENST00000374152+3191967_19712571903MotifNote=LXXLL
HgeneARID1Achr1:27059283chr1:27056142ENST00000374152+3192085_20892571903MotifNote=LXXLL
HgeneARID1Achr1:27059283chr1:27056142ENST00000374152+319295_2992571903MotifNote=LXXLL
HgeneARID1Achr1:27059283chr1:27056142ENST00000457599+4201368_13876402069MotifNuclear localization signal
HgeneARID1Achr1:27059283chr1:27056142ENST00000457599+4201709_17136402069MotifNote=LXXLL
HgeneARID1Achr1:27059283chr1:27056142ENST00000457599+4201967_19716402069MotifNote=LXXLL
HgeneARID1Achr1:27059283chr1:27056142ENST00000457599+4202085_20896402069MotifNote=LXXLL
TgeneARID1Achr1:27059283chr1:27056142ENST00000324856+020295_2993792286MotifNote=LXXLL
TgeneARID1Achr1:27059283chr1:27056142ENST00000457599+020295_2993792069MotifNote=LXXLL


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FusionGeneSequence for ARID1A_ARID1A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.

* Fusion transcript sequences (only coding sequence (CDS) region).

* Fusion transcript sequences (Full-length transcript).

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FusionGenePPI for ARID1A_ARID1A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
ARID1AKLF1, GATA1, SMARCB1, SMARCA4, SMARCA2, ING1, SMARCE1, PBRM1, SMARCC2, SMARCC1, PGR, BCL7C, HIC1, CUL2, ARID1B, SMAD2, SMAD3, CARM1, ADNP, RARA, SOX2, CHD7, SMARCD1, TP53, ELAVL1, SIRT7, TFAP4, CUL3, SMARCD2, ACTL6A, SMARCD3, PHF10, ECT2, YAP1, ITCH, NEDD4, SHMT2, MOV10, NXF1, EED, DPF3, DPF2, SS18, UNK, BCL7A, BCL7B, ESR1, NCOA1, RARB, RARG, EWSR1, SNW1, CDC5L, CUL1, SKP1, NFATC1, NFATC2, TOP1, CHEK1, VHL, EYA2, NR3C1, AR, ALDH2, TRIM25ARID1AKLF1, GATA1, SMARCB1, SMARCA4, SMARCA2, ING1, SMARCE1, PBRM1, SMARCC2, SMARCC1, PGR, BCL7C, HIC1, CUL2, ARID1B, SMAD2, SMAD3, CARM1, ADNP, RARA, SOX2, CHD7, SMARCD1, TP53, ELAVL1, SIRT7, TFAP4, CUL3, SMARCD2, ACTL6A, SMARCD3, PHF10, ECT2, YAP1, ITCH, NEDD4, SHMT2, MOV10, NXF1, EED, DPF3, DPF2, SS18, UNK, BCL7A, BCL7B, ESR1, NCOA1, RARB, RARG, EWSR1, SNW1, CDC5L, CUL1, SKP1, NFATC1, NFATC2, TOP1, CHEK1, VHL, EYA2, NR3C1, AR, ALDH2, TRIM25


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for ARID1A_ARID1A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ARID1A_ARID1A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneARID1AC0038356Stomach Neoplasms3CTD_human
HgeneARID1AC2239176Liver carcinoma3CTD_human
HgeneARID1AC0001418Adenocarcinoma1CTD_human
HgeneARID1AC0005695Bladder Neoplasm1CTD_human
HgeneARID1AC0006413Burkitt Lymphoma1CTD_human
HgeneARID1AC0007138Carcinoma, Transitional Cell1CTD_human
HgeneARID1AC0010606Adenoid Cystic Carcinoma1CTD_human
HgeneARID1AC0014170Endometrial Neoplasms1CTD_human
HgeneARID1AC0027819Neuroblastoma1CTD_human
HgeneARID1AC0036920Sezary Syndrome1CTD_human
HgeneARID1AC0079772T-Cell Lymphoma1CTD_human
HgeneARID1AC0079773Lymphoma, T-Cell, Cutaneous1CTD_human
HgeneARID1AC0206698Cholangiocarcinoma1CTD_human
HgeneARID1AC0265338Coffin-Siris syndrome1CTD_human;ORPHANET
HgeneARID1AC0279628Adenocarcinoma Of Esophagus1CTD_human
HgeneARID1AC0920269Microsatellite Instability1CTD_human
HgeneARID1AC2931822Nasopharyngeal carcinoma1CTD_human
TgeneARID1AC0038356Stomach Neoplasms3CTD_human
TgeneARID1AC2239176Liver carcinoma3CTD_human
TgeneARID1AC0001418Adenocarcinoma1CTD_human
TgeneARID1AC0005695Bladder Neoplasm1CTD_human
TgeneARID1AC0006413Burkitt Lymphoma1CTD_human
TgeneARID1AC0007138Carcinoma, Transitional Cell1CTD_human
TgeneARID1AC0010606Adenoid Cystic Carcinoma1CTD_human
TgeneARID1AC0014170Endometrial Neoplasms1CTD_human
TgeneARID1AC0027819Neuroblastoma1CTD_human
TgeneARID1AC0036920Sezary Syndrome1CTD_human
TgeneARID1AC0079772T-Cell Lymphoma1CTD_human
TgeneARID1AC0079773Lymphoma, T-Cell, Cutaneous1CTD_human
TgeneARID1AC0206698Cholangiocarcinoma1CTD_human
TgeneARID1AC0265338Coffin-Siris syndrome1CTD_human;ORPHANET
TgeneARID1AC0279628Adenocarcinoma Of Esophagus1CTD_human
TgeneARID1AC0920269Microsatellite Instability1CTD_human
TgeneARID1AC2931822Nasopharyngeal carcinoma1CTD_human