|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 25604 |
FusionGeneSummary for OSR2_GOLIM4 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: OSR2_GOLIM4 | Fusion gene ID: 25604 | Hgene | Tgene | Gene symbol | OSR2 | GOLIM4 | Gene ID | 116039 | 27333 |
| Gene name | odd-skipped related transciption factor 2 | golgi integral membrane protein 4 | |
| Synonyms | - | GIMPC|GOLPH4|GPP130|P138 | |
| Cytomap | 8q22.2 | 3q26.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | protein odd-skipped-related 2odd-skipped related 2 | Golgi integral membrane protein 4130 kDa golgi-localized phosphoproteincis Golgi-localized calcium-binding proteingolgi integral membrane protein, cisgolgi phosphoprotein 4golgi phosphoprotein of 130 kDagolgi-localized phosphoprotein of 130 kDatype | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | Q8N2R0 | O00461 | |
| Ensembl transtripts involved in fusion gene | ENST00000520791, ENST00000523368, ENST00000297565, ENST00000435298, ENST00000522510, ENST00000457907, | ENST00000470487, ENST00000309027, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 4 X 4 X 3=48 |
| # samples | 3 | 6 | |
| ** MAII score | log2(3/1*10)=4.90689059560852 | log2(6/48*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: OSR2 [Title/Abstract] AND GOLIM4 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | AA568260 | OSR2 | chr8 | 99964222 | - | GOLIM4 | chr3 | 167761209 | + | ||
| ChiTaRS3.1 | BF591387 | OSR2 | chr8 | 99964222 | - | GOLIM4 | chr3 | 167761209 | + | ||
| ChiTaRS3.1 | AW973843 | OSR2 | chr8 | 99964222 | - | GOLIM4 | chr3 | 167761209 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000520791 | ENST00000470487 | OSR2 | chr8 | 99964222 | - | GOLIM4 | chr3 | 167761209 | + |
| intron-3CDS | ENST00000520791 | ENST00000309027 | OSR2 | chr8 | 99964222 | - | GOLIM4 | chr3 | 167761209 | + |
| intron-3CDS | ENST00000523368 | ENST00000470487 | OSR2 | chr8 | 99964222 | - | GOLIM4 | chr3 | 167761209 | + |
| intron-3CDS | ENST00000523368 | ENST00000309027 | OSR2 | chr8 | 99964222 | - | GOLIM4 | chr3 | 167761209 | + |
| 3UTR-3CDS | ENST00000297565 | ENST00000470487 | OSR2 | chr8 | 99964222 | - | GOLIM4 | chr3 | 167761209 | + |
| 3UTR-3CDS | ENST00000297565 | ENST00000309027 | OSR2 | chr8 | 99964222 | - | GOLIM4 | chr3 | 167761209 | + |
| 3UTR-3CDS | ENST00000435298 | ENST00000470487 | OSR2 | chr8 | 99964222 | - | GOLIM4 | chr3 | 167761209 | + |
| 3UTR-3CDS | ENST00000435298 | ENST00000309027 | OSR2 | chr8 | 99964222 | - | GOLIM4 | chr3 | 167761209 | + |
| intron-3CDS | ENST00000522510 | ENST00000470487 | OSR2 | chr8 | 99964222 | - | GOLIM4 | chr3 | 167761209 | + |
| intron-3CDS | ENST00000522510 | ENST00000309027 | OSR2 | chr8 | 99964222 | - | GOLIM4 | chr3 | 167761209 | + |
| intron-3CDS | ENST00000457907 | ENST00000470487 | OSR2 | chr8 | 99964222 | - | GOLIM4 | chr3 | 167761209 | + |
| intron-3CDS | ENST00000457907 | ENST00000309027 | OSR2 | chr8 | 99964222 | - | GOLIM4 | chr3 | 167761209 | + |
Top |
FusionProtFeatures for OSR2_GOLIM4 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| OSR2 | GOLIM4 |