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Fusion gene ID: 25395 |
FusionGeneSummary for OIP5-AS1_ITGB5 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: OIP5-AS1_ITGB5 | Fusion gene ID: 25395 | Hgene | Tgene | Gene symbol | OIP5-AS1 | ITGB5 | Gene ID | 729082 | 3693 |
| Gene name | OIP5 antisense RNA 1 | integrin subunit beta 5 | |
| Synonyms | cyrano|linc-OIP5 | - | |
| Cytomap | 15q15.1 | 3q21.2 | |
| Type of gene | ncRNA | protein-coding | |
| Description | OIP5 antisense RNA 1 (non-protein coding) | integrin beta-5testis secretory sperm-binding protein Li 217p | |
| Modification date | 20180428 | 20180523 | |
| UniProtAcc | P18084 | ||
| Ensembl transtripts involved in fusion gene | ENST00000500949, | ENST00000296181, ENST00000461306, | |
| Fusion gene scores | * DoF score | 3 X 3 X 1=9 | 3 X 3 X 2=18 |
| # samples | 3 | 3 | |
| ** MAII score | log2(3/9*10)=1.73696559416621 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: OIP5-AS1 [Title/Abstract] AND ITGB5 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | DA453768 | OIP5-AS1 | chr15 | 41578299 | + | ITGB5 | chr3 | 124578293 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-3CDS | ENST00000500949 | ENST00000296181 | OIP5-AS1 | chr15 | 41578299 | + | ITGB5 | chr3 | 124578293 | - |
| 3UTR-intron | ENST00000500949 | ENST00000461306 | OIP5-AS1 | chr15 | 41578299 | + | ITGB5 | chr3 | 124578293 | - |
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FusionProtFeatures for OIP5-AS1_ITGB5 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| OIP5-AS1 | ITGB5 |