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Fusion gene ID: 25121 |
FusionGeneSummary for NUDT5_ZMYND11 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: NUDT5_ZMYND11 | Fusion gene ID: 25121 | Hgene | Tgene | Gene symbol | NUDT5 | ZMYND11 | Gene ID | 11164 | 10771 |
| Gene name | nudix hydrolase 5 | zinc finger MYND-type containing 11 | |
| Synonyms | YSA1|YSA1H|YSAH1|hNUDT5 | BRAM1|BS69|MRD30 | |
| Cytomap | 10p14 | 10p15.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ADP-sugar pyrophosphatase8-oxo-dGDP phosphatasenuclear ATP-synthesis protein NUDIX5nudix (nucleoside diphosphate linked moiety X)-type motif 5 | zinc finger MYND domain-containing protein 11adenovirus 5 E1A-binding proteinbone morphogenetic protein receptor-associated molecule 1 | |
| Modification date | 20180519 | 20180522 | |
| UniProtAcc | Q9UKK9 | Q15326 | |
| Ensembl transtripts involved in fusion gene | ENST00000491614, ENST00000378937, ENST00000537776, ENST00000378952, ENST00000378940, ENST00000378927, | ENST00000381602, ENST00000397962, ENST00000309776, ENST00000509513, ENST00000397959, ENST00000381591, ENST00000403354, ENST00000381607, ENST00000402736, ENST00000602682, ENST00000381604, ENST00000381584, ENST00000558098, ENST00000545619, ENST00000535374, ENST00000473115, | |
| Fusion gene scores | * DoF score | 2 X 2 X 1=4 | 6 X 5 X 6=180 |
| # samples | 2 | 7 | |
| ** MAII score | log2(2/4*10)=2.32192809488736 | log2(7/180*10)=-1.36257007938471 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: NUDT5 [Title/Abstract] AND ZMYND11 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | NUDT5 | GO:0006338 | chromatin remodeling | 27257257 |
| Hgene | NUDT5 | GO:0009191 | ribonucleoside diphosphate catabolic process | 18462755|19699693|21389046 |
| Hgene | NUDT5 | GO:0019303 | D-ribose catabolic process | 21389046 |
| Hgene | NUDT5 | GO:1990966 | ATP generation from poly-ADP-D-ribose | 27257257 |
| Tgene | ZMYND11 | GO:0051607 | defense response to virus | 26845565 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | DC322982 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-5UTR | ENST00000491614 | ENST00000381602 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000491614 | ENST00000397962 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000491614 | ENST00000309776 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000491614 | ENST00000509513 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000491614 | ENST00000397959 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000491614 | ENST00000381591 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000491614 | ENST00000403354 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000491614 | ENST00000381607 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000491614 | ENST00000402736 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000491614 | ENST00000602682 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000491614 | ENST00000381604 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000491614 | ENST00000381584 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-intron | ENST00000491614 | ENST00000558098 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-intron | ENST00000491614 | ENST00000545619 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-intron | ENST00000491614 | ENST00000535374 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-intron | ENST00000491614 | ENST00000473115 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378937 | ENST00000381602 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378937 | ENST00000397962 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378937 | ENST00000309776 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378937 | ENST00000509513 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378937 | ENST00000397959 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378937 | ENST00000381591 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378937 | ENST00000403354 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378937 | ENST00000381607 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378937 | ENST00000402736 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378937 | ENST00000602682 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378937 | ENST00000381604 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378937 | ENST00000381584 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-intron | ENST00000378937 | ENST00000558098 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-intron | ENST00000378937 | ENST00000545619 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-intron | ENST00000378937 | ENST00000535374 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-intron | ENST00000378937 | ENST00000473115 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000537776 | ENST00000381602 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000537776 | ENST00000397962 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000537776 | ENST00000309776 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000537776 | ENST00000509513 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000537776 | ENST00000397959 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000537776 | ENST00000381591 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000537776 | ENST00000403354 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000537776 | ENST00000381607 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000537776 | ENST00000402736 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000537776 | ENST00000602682 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000537776 | ENST00000381604 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000537776 | ENST00000381584 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-intron | ENST00000537776 | ENST00000558098 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-intron | ENST00000537776 | ENST00000545619 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-intron | ENST00000537776 | ENST00000535374 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-intron | ENST00000537776 | ENST00000473115 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5UTR-5UTR | ENST00000378952 | ENST00000381602 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5UTR-5UTR | ENST00000378952 | ENST00000397962 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5UTR-5UTR | ENST00000378952 | ENST00000309776 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5UTR-5UTR | ENST00000378952 | ENST00000509513 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5UTR-5UTR | ENST00000378952 | ENST00000397959 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5UTR-5UTR | ENST00000378952 | ENST00000381591 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5UTR-5UTR | ENST00000378952 | ENST00000403354 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5UTR-5UTR | ENST00000378952 | ENST00000381607 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5UTR-5UTR | ENST00000378952 | ENST00000402736 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5UTR-5UTR | ENST00000378952 | ENST00000602682 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5UTR-5UTR | ENST00000378952 | ENST00000381604 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5UTR-5UTR | ENST00000378952 | ENST00000381584 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5UTR-intron | ENST00000378952 | ENST00000558098 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5UTR-intron | ENST00000378952 | ENST00000545619 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5UTR-intron | ENST00000378952 | ENST00000535374 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5UTR-intron | ENST00000378952 | ENST00000473115 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378940 | ENST00000381602 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378940 | ENST00000397962 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378940 | ENST00000309776 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378940 | ENST00000509513 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378940 | ENST00000397959 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378940 | ENST00000381591 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378940 | ENST00000403354 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378940 | ENST00000381607 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378940 | ENST00000402736 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378940 | ENST00000602682 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378940 | ENST00000381604 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378940 | ENST00000381584 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-intron | ENST00000378940 | ENST00000558098 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-intron | ENST00000378940 | ENST00000545619 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-intron | ENST00000378940 | ENST00000535374 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-intron | ENST00000378940 | ENST00000473115 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378927 | ENST00000381602 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378927 | ENST00000397962 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378927 | ENST00000309776 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378927 | ENST00000509513 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378927 | ENST00000397959 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378927 | ENST00000381591 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378927 | ENST00000403354 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378927 | ENST00000381607 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378927 | ENST00000402736 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378927 | ENST00000602682 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378927 | ENST00000381604 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-5UTR | ENST00000378927 | ENST00000381584 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-intron | ENST00000378927 | ENST00000558098 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-intron | ENST00000378927 | ENST00000545619 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-intron | ENST00000378927 | ENST00000535374 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
| 5CDS-intron | ENST00000378927 | ENST00000473115 | NUDT5 | chr10 | 12228228 | - | ZMYND11 | chr10 | 225932 | + |
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FusionProtFeatures for NUDT5_ZMYND11 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| NUDT5 | ZMYND11 |