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Fusion gene ID: 25006 |
FusionGeneSummary for NTN4_KTN1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: NTN4_KTN1 | Fusion gene ID: 25006 | Hgene | Tgene | Gene symbol | NTN4 | KTN1 | Gene ID | 59277 | 3895 |
| Gene name | netrin 4 | kinectin 1 | |
| Synonyms | PRO3091 | CG1|KNT|MU-RMS-40.19 | |
| Cytomap | 12q22 | 14q22.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | netrin-4beta-netrinhepar-derived netrin-like protein | kinectinCG-1 antigenkinesin receptor | |
| Modification date | 20180519 | 20180522 | |
| UniProtAcc | Q9HB63 | Q86UP2 | |
| Ensembl transtripts involved in fusion gene | ENST00000343702, ENST00000344911, ENST00000538383, ENST00000553059, ENST00000552603, | ENST00000395309, ENST00000413890, ENST00000438792, ENST00000395314, ENST00000395308, ENST00000395311, ENST00000416613, ENST00000554507, ENST00000555573, | |
| Fusion gene scores | * DoF score | 8 X 6 X 4=192 | 6 X 9 X 3=162 |
| # samples | 7 | 9 | |
| ** MAII score | log2(7/192*10)=-1.45567948377619 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(9/162*10)=-0.84799690655495 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: NTN4 [Title/Abstract] AND KTN1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BE147087 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-intron | ENST00000343702 | ENST00000395309 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000343702 | ENST00000413890 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000343702 | ENST00000438792 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000343702 | ENST00000395314 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000343702 | ENST00000395308 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000343702 | ENST00000395311 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000343702 | ENST00000416613 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000343702 | ENST00000554507 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000343702 | ENST00000555573 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000344911 | ENST00000395309 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000344911 | ENST00000413890 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000344911 | ENST00000438792 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000344911 | ENST00000395314 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000344911 | ENST00000395308 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000344911 | ENST00000395311 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000344911 | ENST00000416613 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000344911 | ENST00000554507 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000344911 | ENST00000555573 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000538383 | ENST00000395309 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000538383 | ENST00000413890 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000538383 | ENST00000438792 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000538383 | ENST00000395314 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000538383 | ENST00000395308 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000538383 | ENST00000395311 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000538383 | ENST00000416613 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000538383 | ENST00000554507 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000538383 | ENST00000555573 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000553059 | ENST00000395309 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000553059 | ENST00000413890 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000553059 | ENST00000438792 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000553059 | ENST00000395314 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000553059 | ENST00000395308 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000553059 | ENST00000395311 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000553059 | ENST00000416613 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000553059 | ENST00000554507 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000553059 | ENST00000555573 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000552603 | ENST00000395309 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000552603 | ENST00000413890 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000552603 | ENST00000438792 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000552603 | ENST00000395314 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000552603 | ENST00000395308 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000552603 | ENST00000395311 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000552603 | ENST00000416613 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000552603 | ENST00000554507 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
| intron-intron | ENST00000552603 | ENST00000555573 | NTN4 | chr12 | 96126188 | - | KTN1 | chr14 | 56137407 | - |
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FusionProtFeatures for NTN4_KTN1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| NTN4 | KTN1 |