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Fusion gene ID: 24790 |
FusionGeneSummary for NR2F1-AS1_ITPR3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: NR2F1-AS1_ITPR3 | Fusion gene ID: 24790 | Hgene | Tgene | Gene symbol | NR2F1-AS1 | ITPR3 | Gene ID | 441094 | 3710 |
| Gene name | NR2F1 antisense RNA 1 | inositol 1,4,5-trisphosphate receptor type 3 | |
| Synonyms | - | IP3R|IP3R3 | |
| Cytomap | 5q15 | 6p21.31 | |
| Type of gene | ncRNA | protein-coding | |
| Description | - | inositol 1,4,5-trisphosphate receptor type 3IP3 receptorinositol 1,4,5-triphosphate receptor, type 3insP3R3type 3 InsP3 receptor | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q14573 | ||
| Ensembl transtripts involved in fusion gene | ENST00000607797, ENST00000606233, ENST00000606739, ENST00000510254, ENST00000607831, ENST00000606165, ENST00000606188, ENST00000607195, ENST00000607112, ENST00000606696, ENST00000504474, ENST00000507963, ENST00000513055, | ENST00000374316, ENST00000605930, | |
| Fusion gene scores | * DoF score | 2 X 2 X 1=4 | 5 X 6 X 2=60 |
| # samples | 2 | 6 | |
| ** MAII score | log2(2/4*10)=2.32192809488736 | log2(6/60*10)=0 | |
| Context | PubMed: NR2F1-AS1 [Title/Abstract] AND ITPR3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | ITPR3 | GO:0051592 | response to calcium ion | 19052258 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BE159362 | NR2F1-AS1 | chr5 | 92833637 | - | ITPR3 | chr6 | 33647857 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000607797 | ENST00000374316 | NR2F1-AS1 | chr5 | 92833637 | - | ITPR3 | chr6 | 33647857 | + |
| intron-3CDS | ENST00000607797 | ENST00000605930 | NR2F1-AS1 | chr5 | 92833637 | - | ITPR3 | chr6 | 33647857 | + |
| intron-3CDS | ENST00000606233 | ENST00000374316 | NR2F1-AS1 | chr5 | 92833637 | - | ITPR3 | chr6 | 33647857 | + |
| intron-3CDS | ENST00000606233 | ENST00000605930 | NR2F1-AS1 | chr5 | 92833637 | - | ITPR3 | chr6 | 33647857 | + |
| intron-3CDS | ENST00000606739 | ENST00000374316 | NR2F1-AS1 | chr5 | 92833637 | - | ITPR3 | chr6 | 33647857 | + |
| intron-3CDS | ENST00000606739 | ENST00000605930 | NR2F1-AS1 | chr5 | 92833637 | - | ITPR3 | chr6 | 33647857 | + |
| intron-3CDS | ENST00000510254 | ENST00000374316 | NR2F1-AS1 | chr5 | 92833637 | - | ITPR3 | chr6 | 33647857 | + |
| intron-3CDS | ENST00000510254 | ENST00000605930 | NR2F1-AS1 | chr5 | 92833637 | - | ITPR3 | chr6 | 33647857 | + |
| intron-3CDS | ENST00000607831 | ENST00000374316 | NR2F1-AS1 | chr5 | 92833637 | - | ITPR3 | chr6 | 33647857 | + |
| intron-3CDS | ENST00000607831 | ENST00000605930 | NR2F1-AS1 | chr5 | 92833637 | - | ITPR3 | chr6 | 33647857 | + |
| intron-3CDS | ENST00000606165 | ENST00000374316 | NR2F1-AS1 | chr5 | 92833637 | - | ITPR3 | chr6 | 33647857 | + |
| intron-3CDS | ENST00000606165 | ENST00000605930 | NR2F1-AS1 | chr5 | 92833637 | - | ITPR3 | chr6 | 33647857 | + |
| intron-3CDS | ENST00000606188 | ENST00000374316 | NR2F1-AS1 | chr5 | 92833637 | - | ITPR3 | chr6 | 33647857 | + |
| intron-3CDS | ENST00000606188 | ENST00000605930 | NR2F1-AS1 | chr5 | 92833637 | - | ITPR3 | chr6 | 33647857 | + |
| intron-3CDS | ENST00000607195 | ENST00000374316 | NR2F1-AS1 | chr5 | 92833637 | - | ITPR3 | chr6 | 33647857 | + |
| intron-3CDS | ENST00000607195 | ENST00000605930 | NR2F1-AS1 | chr5 | 92833637 | - | ITPR3 | chr6 | 33647857 | + |
| intron-3CDS | ENST00000607112 | ENST00000374316 | NR2F1-AS1 | chr5 | 92833637 | - | ITPR3 | chr6 | 33647857 | + |
| intron-3CDS | ENST00000607112 | ENST00000605930 | NR2F1-AS1 | chr5 | 92833637 | - | ITPR3 | chr6 | 33647857 | + |
| intron-3CDS | ENST00000606696 | ENST00000374316 | NR2F1-AS1 | chr5 | 92833637 | - | ITPR3 | chr6 | 33647857 | + |
| intron-3CDS | ENST00000606696 | ENST00000605930 | NR2F1-AS1 | chr5 | 92833637 | - | ITPR3 | chr6 | 33647857 | + |
| intron-3CDS | ENST00000504474 | ENST00000374316 | NR2F1-AS1 | chr5 | 92833637 | - | ITPR3 | chr6 | 33647857 | + |
| intron-3CDS | ENST00000504474 | ENST00000605930 | NR2F1-AS1 | chr5 | 92833637 | - | ITPR3 | chr6 | 33647857 | + |
| intron-3CDS | ENST00000507963 | ENST00000374316 | NR2F1-AS1 | chr5 | 92833637 | - | ITPR3 | chr6 | 33647857 | + |
| intron-3CDS | ENST00000507963 | ENST00000605930 | NR2F1-AS1 | chr5 | 92833637 | - | ITPR3 | chr6 | 33647857 | + |
| intron-3CDS | ENST00000513055 | ENST00000374316 | NR2F1-AS1 | chr5 | 92833637 | - | ITPR3 | chr6 | 33647857 | + |
| intron-3CDS | ENST00000513055 | ENST00000605930 | NR2F1-AS1 | chr5 | 92833637 | - | ITPR3 | chr6 | 33647857 | + |
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FusionProtFeatures for NR2F1-AS1_ITPR3 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| NR2F1-AS1 | ITPR3 |