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Fusion gene ID: 24743 |
FusionGeneSummary for NPNT_GSTCD |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: NPNT_GSTCD | Fusion gene ID: 24743 | Hgene | Tgene | Gene symbol | NPNT | GSTCD | Gene ID | 255743 | 79807 |
| Gene name | nephronectin | glutathione S-transferase C-terminal domain containing | |
| Synonyms | EGFL6L|POEM | - | |
| Cytomap | 4q24 | 4q24 | |
| Type of gene | protein-coding | protein-coding | |
| Description | nephronectinpreosteoblast EGF-like repeat protein with MAM domain | glutathione S-transferase C-terminal domain-containing protein | |
| Modification date | 20180527 | 20180523 | |
| UniProtAcc | Q6UXI9 | Q8NEC7 | |
| Ensembl transtripts involved in fusion gene | ENST00000379987, ENST00000453617, ENST00000427316, ENST00000514622, ENST00000305572, ENST00000506666, ENST00000513430, | ENST00000515255, ENST00000394730, ENST00000515279, ENST00000360505, ENST00000394728, ENST00000507281, | |
| Fusion gene scores | * DoF score | 3 X 3 X 2=18 | 4 X 2 X 3=24 |
| # samples | 3 | 4 | |
| ** MAII score | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(4/24*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: NPNT [Title/Abstract] AND GSTCD [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LGG | TCGA-QH-A6CV-01A | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-3UTR | ENST00000379987 | ENST00000515255 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-3UTR | ENST00000379987 | ENST00000394730 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-3UTR | ENST00000379987 | ENST00000515279 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-3UTR | ENST00000379987 | ENST00000360505 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-3UTR | ENST00000379987 | ENST00000394728 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-intron | ENST00000379987 | ENST00000507281 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-3UTR | ENST00000453617 | ENST00000515255 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-3UTR | ENST00000453617 | ENST00000394730 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-3UTR | ENST00000453617 | ENST00000515279 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-3UTR | ENST00000453617 | ENST00000360505 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-3UTR | ENST00000453617 | ENST00000394728 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-intron | ENST00000453617 | ENST00000507281 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-3UTR | ENST00000427316 | ENST00000515255 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-3UTR | ENST00000427316 | ENST00000394730 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-3UTR | ENST00000427316 | ENST00000515279 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-3UTR | ENST00000427316 | ENST00000360505 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-3UTR | ENST00000427316 | ENST00000394728 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-intron | ENST00000427316 | ENST00000507281 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-3UTR | ENST00000514622 | ENST00000515255 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-3UTR | ENST00000514622 | ENST00000394730 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-3UTR | ENST00000514622 | ENST00000515279 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-3UTR | ENST00000514622 | ENST00000360505 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-3UTR | ENST00000514622 | ENST00000394728 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-intron | ENST00000514622 | ENST00000507281 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-3UTR | ENST00000305572 | ENST00000515255 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-3UTR | ENST00000305572 | ENST00000394730 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-3UTR | ENST00000305572 | ENST00000515279 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-3UTR | ENST00000305572 | ENST00000360505 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-3UTR | ENST00000305572 | ENST00000394728 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-intron | ENST00000305572 | ENST00000507281 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-3UTR | ENST00000506666 | ENST00000515255 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-3UTR | ENST00000506666 | ENST00000394730 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-3UTR | ENST00000506666 | ENST00000515279 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-3UTR | ENST00000506666 | ENST00000360505 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-3UTR | ENST00000506666 | ENST00000394728 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| 5CDS-intron | ENST00000506666 | ENST00000507281 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| intron-3UTR | ENST00000513430 | ENST00000515255 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| intron-3UTR | ENST00000513430 | ENST00000394730 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| intron-3UTR | ENST00000513430 | ENST00000515279 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| intron-3UTR | ENST00000513430 | ENST00000360505 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| intron-3UTR | ENST00000513430 | ENST00000394728 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
| intron-intron | ENST00000513430 | ENST00000507281 | NPNT | chr4 | 106819158 | + | GSTCD | chr4 | 106744111 | + |
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FusionProtFeatures for NPNT_GSTCD |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| NPNT | GSTCD |