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Fusion gene ID: 24716 |
FusionGeneSummary for NPIPB7_NRBP2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: NPIPB7_NRBP2 | Fusion gene ID: 24716 | Hgene | Tgene | Gene symbol | NPIPB7 | NRBP2 | Gene ID | 440350 | 340371 |
| Gene name | nuclear pore complex interacting protein family member B7 | nuclear receptor binding protein 2 | |
| Synonyms | A-575C2.4|A-761H5.5|NPIPL1 | TRG16|pp9320 | |
| Cytomap | 16p12.1 | 8q24.3 | |
| Type of gene | pseudo | protein-coding | |
| Description | nuclear pore complex-interacting protein-like 1 | nuclear receptor-binding protein 2transformation-related protein 16 | |
| Modification date | 20180329 | 20180523 | |
| UniProtAcc | O75200 | Q9NSY0 | |
| Ensembl transtripts involved in fusion gene | ENST00000452313, | ENST00000442628, ENST00000327830, | |
| Fusion gene scores | * DoF score | 15 X 17 X 1=255 | 3 X 2 X 3=18 |
| # samples | 17 | 3 | |
| ** MAII score | log2(17/255*10)=-0.584962500721156 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: NPIPB7 [Title/Abstract] AND NRBP2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | AA514249 | NPIPB7 | chr16 | 28854237 | + | NRBP2 | chr8 | 144917117 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3UTR | ENST00000452313 | ENST00000442628 | NPIPB7 | chr16 | 28854237 | + | NRBP2 | chr8 | 144917117 | + |
| intron-3UTR | ENST00000452313 | ENST00000327830 | NPIPB7 | chr16 | 28854237 | + | NRBP2 | chr8 | 144917117 | + |
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FusionProtFeatures for NPIPB7_NRBP2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| NPIPB7 | NRBP2 |